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Cleavage Pattern of Embryos and Oxidative Parameters

Is Abnormal Cleavage Pattern of Embryos Associated With Different Oxidative Parameters Compared With That of Normally Cleaving Embryos? A Prospective Cohort Study

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03791931
Enrollment
200
Registered
2019-01-03
Start date
2019-07-07
Completion date
2021-04-01
Last updated
2020-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Brief summary

To investigate prospectively whether embryos with abnormal cleaving pattern have different oxidative parameters from normally cleaving embryos, and to analyze whether these parameters have an association with demographic, laboratory and clinical parameters including treatment outcome.

Detailed description

To investigate prospectively whether embryos with abnormal cleaving pattern have different oxidative parameters from normally cleaving embryos, and to analyze whether these parameters have an association with demographic, laboratory and clinical parameters including treatment outcome.

Interventions

DIAGNOSTIC_TESToxidative stress measurement

oxidative stress measurement

Sponsors

Carmel Medical Center
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients undergoing IVF for the treatment of infertility

Exclusion criteria

* Age \<18 or \>45 years old * Patients with no embryos with direct cleavage

Design outcomes

Primary

MeasureTime frameDescription
implantation rate1 yearImplantation rate (positive BHCG)
clinical pregnancy rate1 yearClinical pregnancy as defined by appearance of gestational sac on ultrasound

Countries

Israel

Contacts

Primary ContactZofnat Wiener, MD
wiener_zofnat@clalit.org.il97248250335

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026