Anesthesia and Analgesia, Pediatrics, Urologic Surgical Procedures
Conditions
Keywords
ESP block, TAP block, pyeloplasty, erector spina plane block, transversus abdominus plane block, flank incision, post-op analgesia, peri-op analgesia
Brief summary
Regional anesthesia decreases the need for intravenous analgesia in the peri-operative period. Erector spinae plane (ESP) and transversus abdominus plane (TAP) blocks are two common regional anesthesia techniques shown to be effective in open abdominal surgeries. We aim to compare effectiveness of ESP block with TAP block for peri-operative analgesia in pediatric open pyeloplasty patients with a flank incision.
Detailed description
Regional anesthesia for effective post-operative pain management is a part of the pediatric Enhanced Recovery After Surgery (ERAS) protocol. Epidural anesthesia is the gold standard for analgesia for open abdominal surgeries, however difficulties in application and possible complications deter clinicians from utilizing this method. Safe and effective alternatives to epidural anesthesia has been a critical and popular focus of clinical research in recent years. Transversus abdominus plane (TAP) block is an alternative technique shown to be effective in pediatric open abdominal surgeries. Erector spinae plane (ESP) block was described as an effective block for multi-dermatome pain after thoracic surgery. It is emerging as a safe and easy-to-perform alternative to epidural anesthesia for pelvic, abdominal and thoracic surgery. During an open pyeloplasty, the flank incision goes through the transversus abdominus plane, where the local anesthetic is injected for TAP block. This may weaken the analgesic effect of the block. In the ESP block, local anesthetic diffuses cranio-caudally through the fascia of erector spinae muscles and the flank incision does not disturb this plane. We aim to compare the effectiveness of ESP block with TAP block in open pyeloplasty patients.
Interventions
DRUGBupivacaine
0.5 ml/kg 0.25% bupivacaine
Sponsors
Aybike Onur Gonen
Ayse Cigdem Tutuncu
Kaya, Guner, M.D.
Rahsan Ozcan
Istanbul University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
1 Years to 10 Years
Healthy volunteers
No
Inclusion criteria
* American Society of Anesthesiologist class I, II or III * Patients scheduled for elective open pyeloplasty surgery
Exclusion criteria
* Local anesthetic allergy or other contraindication to local anesthetic use * Coagulation disorders * History of chronic pain * Patient/Family refusal * History of scoliosis, spinae bifida, abdominal wall defect * Past surgical procedures with abdominal wall incision * Plan to extend the flank incision for additional surgical intervention
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Remifentanil need | During the operation | Intraoperative remifentanil requirement as rescue analgesia |
| Post-operative analgesia need | 24 hours post-operatively | Pain score is assessed with FLACC (Face, Legs, Activity, Cry, Consolability) scale. A score of 2, 3, 4 or 5 warrants for intravenous paracetamol need and a score of 6 and above warrants for intravenous tramadol |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Parental satisfaction with analgesia | 24 hours post-operatively | Parents will be asked how satisfied they are with the patient's pain control: 1. Dissatisfied, 2. Partially satisfied 3. Satisfied |
Countries
Turkey (Türkiye)
Contacts
Primary ContactPinar Kendigelen, Assoc. Prof.
Backup ContactAybike Onur Gonen, MD
Outcome results
None listed