Vaginal Misoprostol Before Intrauterine Contraceptive Device Insertion

Vaginal Misoprostol Before Intrauterine Contraceptive Device Insertion Following Previous Insertion Failure

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03790371

Enrollment

Registered

2018-12-31

Start date

2015-10-01

Completion date

2016-08-01

Last updated

2018-12-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Contraception

Brief summary

the current study was conducted to assess efficacy of vaginal misoprostol before IUD insertion following previous insertion failure

Interventions

DRUGMisoprostol

vaginal misoprostol prior IUD insertion

DRUGPlacebos

vaginal placebo tablet prior IUD insertion

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

TRIPLE (Subject, Caregiver, Investigator)

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 44 Years

Healthy volunteers

Inclusion criteria

One previous failed attempt of IUD insertion.

Exclusion criteria

1. Uterine fibroid distorting the cavity. 2. Anatomical uterine abnormality with distortion of the cavity 3. Current pelvic inflammatory disease or recently treated pelvic inflammatory disease (PID) in the last three months. 4. Current purulent cervicitis (chlamydia or gonorrhea). 5. Immediately after septic abortion. 6. Uterus size less than 6 cm and more than 9 cm.

Design outcomes

Primary

Measure	Time frame	Description
the success rate for IUD insertion.	four hours after misoprostol dose	the success of IUD insertion after previous attempt failure

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026