Bladder Cancer
Conditions
Brief summary
This research is designed to investigate the prognostic and predictive value of CD155 in muscle invasive bladder cancer.
Interventions
DRUGAdjuvant chemotherapy
adjuvant chemotherapy using Gemcitabine plus Cisplatin
Sponsors
Fudan University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* patients with non-metastatic muscle invasive bladder cancer * pathology confirmed urothelial carcinoma * underwent cystectomy and pelvic lymph node dissection
Exclusion criteria
* not enough tissue for immunohistochemistry * patients with a second neoplasm
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Recurrence free survival | 2018.1.1-2023.12.31 | Time to recurrence or metastasis |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Overall survival | 2018.1.1-2028.1.1 | Time to death |
| Benefit from neoadjuvant chemotherapy | 2018.1.1-2028.1.1 | response to neoadjuvant chemotherapy |
| Benefit from adjuvant chemotherapy | 2018.1.1-2028.1.1 | Survival analysis grouped by adjuvant chemotherapy |
Countries
China
Outcome results
None listed