Critical Care, Critical Illness, Exercise Therapy, Frailty, Intensive Care Unit, Outcome Assessment, Physical and Rehabilitation Medicine, Rehabilitation
Conditions
Keywords
Early Mobilization, Early Rehabilitation, Functional Status, Functional Outcome, Patient Outcome, Intensive Care, Critical Care Outcomes
Brief summary
This is a prospective analysis of patient registry data of intensive care patients. The aim is to investigate if frailty is a predictor of decline of functional status of critically ill patients during their hospital stay.
Detailed description
Elderly critical-ill patients with a high frailty level are becoming increasingly important in the ICU and the health system. Especially, questions about the course of the individual proceeding, withhold of therapy and level of care are controversial among caretakers, as outcome and functional independence remain still unclear in these patients. This applies particularly in view of the fact that large studies such as VIP1 showed an inverse association of high frailty classes with short-term survival. Our main objective in this study was to focus on functional outcome and independency measured by Barthel Index after ICU stay regarding frailty, the effect of critical care and severity and prognosis of the disease.
Interventions
None listed
Sponsors
Technical University of Munich
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* intensive care stay \> 48 hours
Exclusion criteria
* none
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Probability not to deteriorate in functional status during the hospital stay | a median of 30 days | Analysis of the course of functional status measured by the Barthel Score sub-components transfer and ambulation during the hospital stay. The Scale ranges from 0 (no transfer) to 15 (transfer to chair and back) for transfer and from 0 (no ambulation) to 15 (coming into stand and walk 50m without supervision) for ambulation. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hospital length of stay | a median of 30 days | Duration of stay in the hospital |
| Rate of discharge disposition to home | 1 day | Rate of participants being discharged home after the hospital stay. |
| ICU mortality | a median of 11 days | Expired during the intensive care stay |
| ICU length of stay | a median of 11 days | Duration of stay on intensive care |
| Change in Functional status before hospital admission to ICU discharge | a median of 20 days | Analysis of the change of functional status measured by the Barthel Score sub-components transfer and ambulation from before hospital admission to ICU discharge. The Scale ranges from 0 (no transfer) to 15 (transfer to chair and back) for transfer and from 0 (no ambulation) to 15 (coming into stand and walk 50m without supervision) for ambulation. |
| Change in Functional status before hospital admission to hospital discharge | a median of 30 days | Analysis of the change of functional status measured by the Barthel Score sub-components transfer and ambulation from before hospital admission to hospital discharge. The Scale ranges from 0 (no transfer) to 15 (transfer to chair and back) for transfer and from 0 (no ambulation) to 15 (coming into stand and walk 50m without supervision) for ambulation. |
| Hospital mortality | a median of 22 days | Expired during the hospital stay |
Countries
Germany
Outcome results
None listed