Delta Shock Index in Predicting Massive Transfusion

The Relationship of Delta Shock Index With the Requirement of Blood Transfusion and Clinical Outcome of Adult Trauma Patients

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03786705

Enrollment

7957

Registered

2018-12-26

Start date

2018-06-05

Completion date

2018-12-20

Last updated

2018-12-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trauma Patients Had Not Received Blood Transfusion ≥ 10 U, Trauma Patients Received Blood Transfusion ≥ 10 U

Brief summary

Background: To determine the performance of delta shock index (ΔSI), a change in shock index (SI) upon arrival at the emergency room (ER) from that in the field in predicting the need for massive transfusion (MT) among adult trauma patients with stable blood pressure. Methods: This study included data from all trauma patients aged 20 years and above who were hospitalized from January 1, 2009 to December 31, 2016 and was obtained from the registered trauma database of the hospital. Only patients who were transferred by emergency medical service from the accident site with a systolic blood pressure ≥ 90 mm Hg at the ER were included in this study. The 7,957 enrolled trauma patients were divided into 2 groups, those who had received blood transfusion ≥ 10 U (MT, n = 82) and those who had not (non-MT, n = 7,875). The odds ratios with 95% confidence intervals for associated patient conditions and the odds of need for MT by a given ΔSI were measured. The plot of specific receiver operating characteristic (ROC) curves was used to evaluate the best cutoff point that could predict the patient's probability of receiving MT.

Interventions

OTHERMassive transfusion

Trauma patients who had received blood transfusion≥10 U

OTHERNon-Massive Transfusion

Trauma patients who had received blood transfusion\<10 U

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 100 Years

Healthy volunteers

Inclusion criteria

* Patients who were transferred by emergency medical service (EMS) from the field of accident and had a stable blood pressure (SBP ≥ 90 mmHg) at the ER were included

Exclusion criteria

* Patients who were transferred from other hospitals or arrived by private vehicles. * Patients who had incomplete data * Patients who had an unstable blood pressure (SBP \< 90 mmHg) upon arrival at the ER were also excluded

Design outcomes

Primary

Measure	Time frame	Description
in-hospital mortality	up to 5 months	To measure the outcome of patients.

Countries

Taiwan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026