Pelvic Pain
Conditions
Brief summary
Vaginal microorganisms play an important role in the occurrence and development of many diseases, such as persistent infection of high-risk human papillomavirus (HR-HPV) causing cervical intraepithelial neoplasia and cervical cancer, and the role of microorganisms in chronic prostatitis.
Interventions
OTHERObservation
The patients with the negative results of HPV infection, and assigned to different group according to the CPP manifestation.
Sponsors
Peking Union Medical College Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
MALE
Age
20 Years to 45 Years
Inclusion criteria
* Those are aged 20 to 45 years old, have vaginal intercourse more than 3 years, and aren't in menstrual, pregnancy or puerperium period.
Exclusion criteria
* Those are aged more than 45 years old without HPV infection in the last one year, having no vaginal intercourse, and those can't cooperate the examiner. Women who are HIV or hepatitis B/C positive, have autoimmune disorders and systemic disease (like diabetes mellitus, hormone treatment diseases, severe liver and kidney dysfunction), or have severe mental illness and malignant tumors are also excluded. At the same time, all the participants should meet the following requirements: no vagina douching within last 2 days, no vaginal intercourse within last 3 days, no systemic application of antifungal agents or antibiotics or pessaries within last 14 days of sampling.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Vaginal microbiota difference | one year | Vaginal microbiota difference between the women with or without CPP, and all the cases are cervical HPV negative. |
Countries
China
Contacts
Primary ContactShu Wang
Outcome results
None listed