Optic Neve Sheath Diameter
Conditions
Keywords
Optic Nerve Sheath Diameter Different Position
Brief summary
Intracranial pressure is measured indirectly using optic nerve sheath diameter with ultrasound. It is reported that epidural pressure varies according to different posture ( lateral decubitus vs. sitting position). This study is designed to measure the optic nerve sheath diameter in lateral decubitus and sitting position, respectively.
Detailed description
According to previous study, injection of different volume of local anesthetics (1.0 ml/kg vs. 1.5 ml/kg) during caudal anesthesia, high volume of local anesthetics resulted in significant increase of intracranial pressure (ICP). Increase of ICP can reduce regional cerebral flow and oxygen saturation causing the safety of patients. In addition, increase of ICP can result in headache, syncope, and transient loss of visual acuity. Although it is very invasive method, ICP can be measured directly at the brain parenchyme. Among methods to measure the ICP indirectly, measurement of optic nerve sheath diameter using ultrasound is known to reflect the degree of ICP. It is reported that optic nerve sheath diameter increases when higher volume of medication is injected during epidural anesthesia. Previous reports showed that epidural pressure varies according to different posture. When epidural pressure was measured in patients of spinal stenosis, lumbar flexion showed lower epidural pressure than epidural pressure of lumbar extension. In addition, when epidural pressure was measured in the sitting position, it showed lower pressure than pressure of lateral decubitus.
Interventions
thoracic epidural catheterization with different posture
Sponsors
Keimyung University Dongsan Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
20 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* lung cancer * liver cancer * stomach cancer * pancreas cancer
Exclusion criteria
* coagulopathy * infection * previous spine fusion at thoracic level * previous brain surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| optic nerve sheath diameter change among 4 time period | Baseline, 10 minutes, 20 minutes, 40 minutes after the completion of the intervention | optic nerve sheath diameter change among 4 time period using ultrasound |
Countries
South Korea
Outcome results
None listed