A Registry Study of Biomarkers in Heart Failure

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03784833

Acronym

BIOMS-HF

Enrollment

5000

Registered

2018-12-24

Start date

2016-06-30

Completion date

2024-06-30

Last updated

2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Diseases

Keywords

heart failure

Brief summary

The registry study aims to discover the prognostic value of bio-markers in heart failure

Detailed description

The purpose of this study is to investigate the prognostic value of biomarkers in Heart Failure.Patients with confirmed diagnosis of heart failure are enrolled.The primary outcome is all-cause mortality based on the death certificates. The secondary outcome is readmission for heart failure and all-cause mortality/readmission for heart failure according to the patients' medical records.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* Age greater than or equal to 18 years at the time of admission to the hospital * With symptoms of new-onset or worsening heart failure * Received or is eligible to receive a principal hospital discharge diagnosis of HF * With signs and syndromes as follows: dyspnea at rest or with minimal exertion (dyspnea, orthopnea, or edema)；Rales, peripheral edema, ascites, or pulmonary vascular congestion on chest radiography. * Patients who received packed red blood cells, whole blood, or platelets less than 10 days before the blood sample was taken;

Exclusion criteria

* Have objective evidence of cardiac dysfunction documented either by plasma concentrations of BNP and/or N-terminal pro-brain natriuretic peptide (NT-proBNP) \<35 pg/mL or \<125 pg/ml, respectively * Current known inability to follow instructions or comply with follow-up procedures. * Eligible patients without informed consent form

Design outcomes

Primary

Measure	Time frame	Description
Number of death (all cause)	2 years of follow-up	Number of death within 2 years of discharge

Secondary

Measure	Time frame	Description
Number of rehospitalizations for acute heart failure (HF)	2 years of follow-up	Number of heart failure related hospitalization within 2 years of discharge
Number of death ( all cause) or readmission for heart failure	2 years of follow-up	Number of Death or heart failure related hospitalization within 2 years of discharge

Countries

China

Contacts

Primary ContactYuan Wang, Dr

wangyuan980510@163.com13910161443

Backup ContactBingbing Ke, Dr

1017120710@qq.com15510286857

Outcome results