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Reducing Pain in Emergency Department by Using Veinous Blood Gas Instead of Arterious Blood Gas

Reducing Pain in Emergency Department by Using Veinous Blood Gas Instead of Arterious Blood Gas

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03784664
Acronym
VEINART
Enrollment
100
Registered
2018-12-24
Start date
2019-01-20
Completion date
2019-03-22
Last updated
2019-06-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acid Base Disorder

Brief summary

Blood gases are widely used in emergency and resuscitation services and are the key examination for exploring acid-base balance disorders (using pH, PaCO2 and HCO3 ) and gas exchange disorders (using PaO2 and PaCO2). This examination can be taken from both venous and arterial sample and its analysis depends on the type of blood sample. Currently, several studies have already shown the existence of a good correlation of pH and bicarbonates level between a venous and arterial sample. Thus, when this examination is prescribed for the purpose of highlighting and analyzing an acid-base disorder, venous blood gas is theoretically as efficient as arterial blood gas. Due to the lack of evidence of benefit for the patient or the health care team of a venous blood gas rather than an arterial blood gas in the absence of suspicion of hypoxemia, arterial blood gas is currently the standard of care for the analysis of acid-base disorders. Indeed, among the university hospitals affiliated to the Paris Diderot University, the emergency departments carry out in their vast majority (4 of 5 E.D.) arterial blood gases. Demonstration of the superiority of veinous sample over arterial sample regarding pain could substantially modify current practices. The investigator's main hypothesis is that, in the absence of suspicion of hypoxemia (normal oxygen saturation measured by plethysmography), the realization of a venous blood gas for the evaluation of the acid-base balance in the context of emergencies is less painful for patients, simpler for the health care team and provides sufficient biochemical information for the doctor in comparison with an arterial blood gas.

Interventions

DIAGNOSTIC_TESTArterial blood gas

arterial blood sample with puncture of the radial artery

DIAGNOSTIC_TESTVeinous blood gas

veinous blood sample using peripheral venepuncture

Sponsors

Assistance Publique - Hôpitaux de Paris
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* necessity of blood gas analysis * age \> 18 yo * SpO2\>95% without supplemental oxygen * no altered level of consciousness: Glasgow Coma Scale=15

Exclusion criteria

* Patient under guardianship or curatorship * confusional state or patient unable to understand the protocol * no social security

Design outcomes

Primary

MeasureTime frameDescription
Pain score: Visual Analog ScaleImmediately after blood gas samplePain is self-completed by the patient using a Visual Analog Scale. Visual Analog Scale for Pain is a continuous scale comprised of a line of 100 mm grading pain intensity anchored by no pain (score 0) and worst imaginable pain (score 100)

Secondary

MeasureTime frameDescription
Number of attempts needed to obtain a blood gas sampleImmediately after blood gas sample
Number of different operators needed to obtain a blood gas sampleImmediately after blood gas sample
Ease of blood gas sampling procedureImmediately after blood gas sampleEase of blood gas sampling procedure assessed by the operator using a four-levels likert scale (easy,moderate,difficult very difficult)
Failure of the blood gas sampling procedureImmediately after blood gas sampleImpossibility to obtain a blood gas sample
Quality of information provided by the blood gas analysis: four levels likert scaleImmediately after having received blood gas analysis resultsFour-levels likert scale assessing doctor's satisfaction regarding the quality of gas information provided by the blood gas analysis (very satisfied,satisfied,slightly satisfied,not satisfied

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 17, 2026