Chronic Periodontitis, Generalized
Conditions
Brief summary
Is the non-surgical periodontal therapy can improve glycemic control in type 2 diabetic patients with chronic periodontitis?
Detailed description
The aim of the present study was to monitor the clinical outcomes and the metabolic response of non-surgical periodontal therapy in patients with chronic periodontitis and uncontrolled type 2 diabetes. Regarding clinical and metabolic parameters at baseline, no differences were displayed between two groups. However, at 3-months follow-up period the patients within a test group were demonstrated better clinical outcomes than patients in a control group
Interventions
COMBINATION_PRODUCTamoxicillin 500mg and metronidazole 400mg
metronidazole 400mg and amoxicillin 500mg three times daily for two weeks
Sponsors
Taibah University
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
40 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
Diagnosis of diabetes type 2 for more than five years Type 2 diabetes with HbA1c level from 7% to 9% at the last medical evaluation Diagnosis with chronic periodontitis
Exclusion criteria
Pregnancy * Alcoholism and smoking * Presence of any systemic disorders other than hypertension and diabetes * Diabetic major complications
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| glycosylated haemoglobin (HbA1c) | 3 months | Blood was taken from a peripheral vein to monitor HbA1c using high-performance liquid chromatography |
Outcome results
None listed