Role of Platelet Rich Plasma in Wound Healing
Conditions
Keywords
Platelet rich plasma, disrupted wounds, Obstetrics and Gynecology
Brief summary
Patients with disrupted wounds will either managed as usual or managed by Platelet rich plasma local infiltration in the wound edges
Detailed description
The patients with disrupted surgical wounds will be cleansed, debrided and closed with infiltration of platelet rich plasma in one group and the other group will be closed without infiltration of Platelet rich plasma
Interventions
PROCEDUREPlatelet rich plasma infiltration in the wound edges
platelet rich plasma will be injected in the wound edges
PROCEDUREClosure of wound without platelet rich plasma infiltration
No infiltration of platelet rich plasma is done
Sponsors
Tanta University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Masking description
Patients were not allowed to know allocations
Intervention model description
All cases with disrupted surgical wounds admitted at Obstetrics and Gynecology departments
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* Disrupted surgical wounds after cesarean sections and other gynecological operations * Body mass index 18-25 * Hemoglobin \> 10.5gm/dl * Albumin \>3.5gm/dl
Exclusion criteria
* Medical disorders asDiabetes mellitus (DM), Liver disease or systemic lupus erythymatosus (SLE) * Patient on corticosteriod therapy * Thrombocytopenia * Coagulation disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Complete wound healing | 30 days | time needed for complete wound closure |
| Duration of hospital stay | 30 days | Time during which patient is admitted |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Failure of complete wound healing | 30 days | No complete closure |
| Need fo tertiary suture | 30 days | need to re-operate the case again |
Countries
Egypt
Outcome results
None listed