Bilateral vs. Unilateral Erector Spinae Plane Block

Bilateral vs. Unilateral Erector Spinae Plane Block for Laparoscopic Cholecystectomy; A Randomised Controlled Trial

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03781687

Enrollment

Registered

2018-12-20

Start date

2019-01-02

Completion date

2019-06-29

Last updated

2019-11-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pain, Cholecystitis; Gallstone

Keywords

erector spinae plane block, postoperative pain, laparoscopic cholecystectomy

Brief summary

The importance of multimodal analgesia for postoperative pain management is well known and regional anesthesia techniques are commonly prefferred to provide better analgesia. Erector spinae plane block (ESB) is a new defined and effective regional anesthesia technique. But two injections can be unconfortable for some patients. With this study, we aimed to compare the analgesia effect of bilateral and unilateral ESP block for laparoscopic cholecystectomy.

Interventions

PROCEDUREBilateral ESP Block

Bilateral ESP Block will be performed at T8

PROCEDUREUnilateral ESP Block

Unilateral ESP Block will be performed at T8 (right side)

DEVICEIntravenous Morphine patient controlled analgesia device

24 hour morphine consumption will be recorded

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

PREVENTION

Masking

DOUBLE (Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* ASA I-II patients * Pateints undergoing elective laparoscopic cholecystectomy

Exclusion criteria

* obesity (body mass index \>35 kg/m2) * infection of the skin at the site of needle puncture area * patients with known allergies to any of the study drugs * coagulopathy * recent use of analgesic drugs

Design outcomes

Primary

Measure	Time frame	Description
Morphine consumption	preoperative 24th hour	Morphine consumption will be recorded

Secondary

Measure	Time frame	Description
Numeric Rating Scale	postoperative 24th hour	A NRS involves asking the patient to rate his or her pain from 0 to 10 (11 point scale) with the understanding that 0 is equal to no pain and 10 is equal to worst possible pain.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026