Respiratory Depression
Conditions
Brief summary
To explore the effectiveness of transcutaneous acupuncture electrical stimulation (TAES), a non-invasive modality in improvement of the function of respiration and circulation on elder patient during colonoscopy.
Detailed description
To assess the function of respiratory and circulation before precondition, during colonoscopy and end of the procedure, blood cortisol and catecholamine levels were measured also.The incidence of airway support, application of vasoactive drug or atropine during procedure were recorded in the meantime.
Interventions
DEVICETAES
TAES over acupuncture point neiguan (pericardium 6) for 20min, placebo group only stick the stimulate electrode but no frequency and intensity
Sponsors
RenJi Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. patients aged 65 or older 2. American Society of Anesthesiologists (ASA) grade I\ II 3. consent and voluntary participation in this experiment 4. patients under colonoscopy 5. none allergic to propofol and fentanyl 6. airway assessment for none difficult airway
Exclusion criteria
1. Allergic to propofol, fentanyl. 2. ASA is greater than or equal to grade 3 3. Abnormal respiratory tract may cause severe respiratory obstruction 4. unsatisfactory control of hypertension, systolic pressure over 160 millimeter of mercury (mmHg) or diastolic pressure over 100 mmHg 5. Hypotension, systolic pressure below 90 mmHg, heart rate (HR) \<50bpm or \>100bpm
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The percentage of oxygen saturation | from 20min before lay down to 24hours after performance | The percentage of oxygen saturation between the sedation alone and sedation+TAES have at least 2 difference |
Countries
China
Contacts
Primary Contactchen yongming
Backup ContactLu Qi
Outcome results
None listed