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Changes in Pulpal Blood Flow of Teeth During Leveling and Alignment Stages of Orthodontic Treatment Using Clear Aligners

Changes in Pulpal Blood Flow of Teeth During Leveling and Alignment Stages of Orthodontic Treatment Using Clear Aligners

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03772795
Enrollment
45
Registered
2018-12-11
Start date
2017-01-01
Completion date
2018-04-01
Last updated
2019-01-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alignment

Keywords

Pulpal blood flow, clear aligners, orthodontics

Brief summary

The aims of this study were to: - * Evaluate PBF in upper and lower teeth during orthodontic alignment using fixed appliances (0.014 super elastic NiTi arch wire) at different time intervals (20min, 48h, 72h and 1 month) of initial arch wire placement. * Evaluate the PBF in upper and lower teeth during orthodontic teeth alignment using clear aligners at different time intervals (20min ,48h, 72h and 1 month) of fitting the second aligner (first active aligner). * Compare the PBF changes between the above two different types of orthodontic appliances (fixed appliances and the clear aligners).

Detailed description

Aims: to evaluate the pulpal blood flow (PBF) during orthodontic teeth alignment and leveling using clear aligners (second aligner) and fixed orthodontic appliance at different time intervals of orthodontic force application. Materials and Methods: A total of 45 subjects were subdivided in two groups: group 1: 25 subjects treated with pre-adjusted edgewise fixed appliance with 0.014 inch NiTi as the alignment arch wire and group 2: 20 subjects treated using clear aligner. In both groups, PBF was measured for the upper right and the lower left using Laser Doppler Flowmetry at different time interval (20 minutes, 48 hours, 72 hours, 1 month) after the fitting of the arch wire in group one and after the delivery of the second aligner in group two.

Interventions

OTHEROrthodontic Alignment

Group 1:- Teeth alignment in this group started using round 0.014 NiTi arch wire. The 0.014 NiTi arch wire was placed into the slots of the brackets and tied with elastomers by figure of 8. During this stage, only tipping movement was applied.

Sponsors

Jordan University of Science and Technology
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Intervention model description

Two groups receiving 2 interventions. In the first group patients received fixed orthodontic appliance and in the second, they received clear aligner orthodontic appliance

Eligibility

Sex/Gender
ALL
Age
16 Years to 22 Years
Healthy volunteers
Yes

Inclusion criteria

* Both male and female subjects * 16 or more years old * Class I skeletal malocclusion * mild upper and lower arches crowding.

Exclusion criteria

- * Poor oral hygiene * Previous orthodontic treatment * Active periodontal disease * Missing teeth * Deep carious teeth * Teeth with root resorption * Endodontically treated teeth * History of previous trauma * Restoration on measured teeth * Medical conditions affecting blood vessels * Smoking

Design outcomes

Primary

MeasureTime frameDescription
Pulpal blood flow changes by the use of Laser Doppler Flowmeter (Moor lab, Moor instruments, UK) with a wavelength of 780 nm and a dental probe MP 13 (Moor instruments, UK; 2 fibers, 0.25 mm diameter, centers 0.5 mm spaced apart).20 minutes ,48 hours, 72 hours and 1 monthmillimeter per second

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026