Odontogenic Deep Space Neck Infection
Conditions
Brief summary
The purpose of the study is to evaluate the sensitivity and specificity of the Target Enriched Multiplex (TEM) polymerase chain reaction (PCR) platform for the rapid molecular diagnosis and treatment of odontogenic deep space neck infections.
Interventions
DIAGNOSTIC_TESTTarget Enriched Multiplex PCR (TEM- PCR)
Target Enriched Multiplex PCR (TEM- PCR) assays will be performed and will probe for the typical array of advanced deep space odontogenic infections, as well as MRSA resistance, clindamycin resistance, and the presence of Panton-Valentine leukocidin (PVL) toxin, a toxin produced by some bacteria.
DIAGNOSTIC_TESTMicrobial culture
Standard diagnosis by microbial culture.
Sponsors
Eurofins
The University of Texas Health Science Center, Houston
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients in whom there is clinical and radiographic evidence of an odontogenic deep space neck infection.
Exclusion criteria
* Patients with gross communication between the abscess and the oral cavity will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Specificity as assessed by number of participants who had matching results between TEM-PCR and standard microbial culture | Baseline (at the time the sample was obtained from the patient) |
Countries
United States
Outcome results
None listed