Perceptual Disorders, Recovery of Function, Rehabilitation, Stroke, Virtual Reality Exposure Therapy
Conditions
Brief summary
The purpose of this study is to investigate the effect of virtual prism adaptation therapy on hemispatial neglect in chronic stroke patients. This study is the randomized, double-blind, sham-controlled, cross-over design. Total 10 patients will be allocated randomly to either real virtual prism adaptation therapy or sham therapy with the wash-out period of more than 2 weeks. Two sessions (20min/session) per day, for 5days (total 10 sessions) will be provided. Behavioral outcomes will be measured before and after completing a total of 10 sessions therapy.
Interventions
DEVICEVirtual Prism Adaptation Therapy
Hand trajectory will deviate to the right side in the virtual reality.
DEVICESham Therapy
The therapy is the same as the real virtual prism adaptation therapy, but there will be no deviation of the hand trajectory in the virtual reality.
Sponsors
Bundang Rusk Rehabilitation Specialty Hospital
Seoul National University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* 3 months after stroke onset * 2 or more tests indicative of hemispatial neglect in following 3 tests: 1)line bisection test, 2)Albert's test, 3)Drawing test. * Ability to recognize the target object, hand trajectory in the immersive virtual reality * 16 points or more in the Korean version of mini-mental state examination
Exclusion criteria
* Previous stroke or traumatic brain injury history * Can not cooperate during the therapy, due to delirium or aphasia * Unstable medical conditions * Severe psychiatric symptoms that interfere with the therapy participation (e.g. severe depression, agitation, psychotic symptoms) * Pregnancy * Can not maintain sitting posture
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Behavioral Inattention Test (BIT) Score | Change from Baseline at 5 days | Range: 0(best) to 227(worst) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| BIT Conventional subtest score (BITC) | Change from Baseline at 5 days | Range: 0(best) to 146(worst) |
| BIT Behavioral subtest score (BITB) | Change from Baseline at 5 days | Range: 0(best) to 81(worst) |
| Comb and Razor Test | Change from Baseline at 5 days | Range: 0% deviation (best) to 100% deviation (worst) |
| Catherine Bergego Scale (CBS) | Change from baseline at 5 days | Range: 0 (best) to 30 (worst) |
Countries
South Korea
Outcome results
None listed