Methods of Exercise in Children
Conditions
Brief summary
The purpose of this research study is to understand how different kinds of exercise affect the human body and the health of the heart and lungs.Participants will exercise in different protocols on a bicycle ergometer or treadmill. This research could lead to improved and more accurate fitness assessment and pave the way to an improved personalized exercise program in health and illness.
Detailed description
The purpose of this research study is to understand how different kinds of exercise affect the human body and the health of the heart and lungs. For example, some people like to exercise continuously for relatively long periods of time while others like to exercise for short periods of time with rest periods in between. Children tend to exercise in frequent bouts of brief exercise interspersed with periods of rest. Also, some people like running or treadmill exercise while others like to work out on stationary bicycles. To date, standard exercise testing is based on a century-old paradigm used predominantly for adults that involves maximal exercise protocols (cardiopulmonary exercise testing-CPET). Moreover, different but widely used exercise modalities such as cycle ergometer and treadmills are currently impossible to compare in children, and this has limited the clinical and research application of such testing in the pediatric age-range. A major premise of this laboratory is that laboratory testing of cardiopulmonary fitness in children should be based on protocols that mimic naturally occurring patterns of exercise in children, rather than those that have been artificially employed to assess maximal efforts in adults. This research project designed to begin the process of systematically identifying protocols can be best used for children and young adults. Participants will exercise in different protocols on a bicycle ergometer or treadmill. This research could lead to improved and more accurate fitness assessment and pave the way to an improved personalized exercise program in health and illness.
Interventions
OTHERExercise Training
Comparison of stationary bike and treadmill exercise among children, adolescents and adults
Sponsors
University of California, Irvine
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
7 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* Between the ages of 7-35 years old without any known respiratory, cardiac or metabolic disease * Determined to be in good health by preparticipation history * No evidence of disease or disability that would impair participation in an exercise testing * No chronic prescribed medication
Exclusion criteria
* Other limitation which in the eyes of the physician that would preclude ability to perform exercise testing * Use of illegal drugs or abuse of alcohol * Pregnancy or breastfeeding
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Maximum Oxygen Uptake (VO2) Measurements During Exercise | At least 48 hours | Breath by breath gas exchange VO2 in response to exercise. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Heart Rate (HR) Measurements During Exercise | At least 48 hours | Heart Rate (HR) values in response to exercise |
Countries
United States
Baseline characteristics
| Characteristic | — |
|---|---|
| Age, Categorical <=18 years | 75 Participants |
| Age, Categorical >=65 years | 0 Participants |
| Age, Categorical Between 18 and 65 years | 19 Participants |
| Age, Continuous | 17.9 years STANDARD_DEVIATION 2.1 |
| Race/Ethnicity, Customized Ethnicity (Hispanic/Latino) | 1 Participants |
| Race/Ethnicity, Customized Race (African-American) | 2 Participants |
| Race/Ethnicity, Customized Race (Asian) | 26 Participants |
| Race/Ethnicity, Customized Race (White) | 65 Participants |
| Region of Enrollment United States | 94 participants |
| Sex: Female, Male Female | 16 Participants |
| Sex: Female, Male Male | 18 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk | EG002 affected / at risk | EG003 affected / at risk | EG004 affected / at risk | EG005 affected / at risk |
|---|---|---|---|---|---|---|
| deaths Total, all-cause mortality | 0 / 34 | 0 / 41 | 0 / 19 | 0 / 34 | 0 / 41 | 0 / 19 |
| other Total, other adverse events | 0 / 34 | 0 / 41 | 0 / 19 | 0 / 34 | 0 / 41 | 0 / 19 |
| serious Total, serious adverse events | 0 / 34 | 0 / 41 | 0 / 19 | 0 / 34 | 0 / 41 | 0 / 19 |
Outcome results
None listed