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Proximal Femoral Fractures - Patient Population, Risk Factors, Surgical Performance and Outcome

Proximal Femoral Fractures - Patient Population, Risk Factors, Surgical Performance and Outcome

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03768622
Acronym
ProFi
Enrollment
2906
Registered
2018-12-07
Start date
2018-06-01
Completion date
2021-03-06
Last updated
2021-11-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Proximal Femoral Fracture

Keywords

femoral neck fracture, pertrochanteric femoral fracture, risk factor for proximal femoral fracture

Brief summary

Proximal femoral fractures are a typical pathology in elderly patients after a low-energy trauma. This study analyses preexisting risk factors for proximal femoral fractures as well as for failing to reach the previous functional level, difference in outcome between patients with femoral neck fracture compared to those with pertrochanteric fracture, surgical performance and its significance for the functional outcome, as well as the impact of proximal femoral fractures on patients' one-year independence.

Interventions

PROCEDUREsurgery for pertrochanteric femoral fracture

surgical treatment for proximal femoral fracture with intramedullary nail type Gamma® Nail or similar in case of pertrochanteric fractures

PROCEDUREsurgery for femoral neck fracture

surgical treatment for proximal femoral fracture with a partial hip arthroplasty in case of femoral neck fractures

Sponsors

University Hospital, Basel, Switzerland
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* surgery with intramedullary nail type Gamma® Nail or similar in case of pertrochanteric fractures or * with a partial hip arthroplasty in case of femoral neck fractures

Exclusion criteria

* Clinical follow up at another institution * Documented dissent in study participation

Design outcomes

Primary

MeasureTime frameDescription
Change in Patient clinical outcomefrom date of surgery until 1 year follow up period after surgeryQuantification of Rehospitalizations

Secondary

MeasureTime frameDescription
Change in patient clinical outcome (according Penrod score)preoperatively and at 1 year follow up date after surgeryPenrod score reflects the patients' preoperative functional level and living. Patients are classified concerning their prefracture age (1: \<75 years, 2: 75-84 years, 3 ≥85 years, their ability in performing activities of daily life (ADL) as well as their cognitive status (dementia in clusters 2B and 3D Situation)
Change in radiological outcome: assessment of surgical treatment of pertrochanteric fracturesday of surgical intervention (immediately after surgery) and 1year postoperative (if n.a. min 6 months postoperative)central positioning and insertion of the neck screw
radiological outcome: assessment of surgical treatment of femoral neck fractures1year postoperative (if n.a. min 6 months postoperative)development of periacetabular ossification according to Brooker * A islands of bone within the soft tissues about the hip * B bone spurs originating from the pelvis or proximal end of the femur, leaving at least 1 cm between opposing bone surfaces * C bone spurs originating from the pelvis or proximal end of the femur, reducing the space between opposing bone surfaces to less than 1 cm * D bone ankylosis of the hip
Change in subsidence (radiological outcome: assessment of surgical treatment of femoral neck fractures)1year postoperative (if n.a. min 6 months postoperative)differences in the distance between perpendicular lines drawn to the bisecting axis of the medullary canal, at the top of the femoral head and at the tip of the great trochanter in mm
Change in radiological outcome: assessment of surgical treatment of femoral neck fracturesday of surgical intervention (immediately after surgery) and 1year postoperative (if n.a. min 6 months postoperative)leg-length discrepancy in mm (tangent to inferior pubic rami and tip of greater trochanter, if n.a. insertion of lesser trochanter)

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026