Abortion, Missed
Conditions
Keywords
Missed abortion, Procalcitonin, Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), Leukocyte (WBC)
Brief summary
Aim: The serum procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values will be compared between fertile missed abortion diagnosed pregnants and fertile normal pregnants to determine the presence of subclinical infection in the etiology of missed abortion
Detailed description
The study group will consist of 30 fertile, under 35 years old women having for the first time missed abortus diagnosis in the Obstetrics Department of Obstetrics and Gynecology of Medicine Faculty of Karadeniz Technical University, Medical Faculty of Medicine. As control group, 30 cases with the same trimester, fertile, and under 35 years old who had referred to Obstetrics clinic, who had no systemic disease, will be included in the study. Blood samples will be collected at the time of diagnosis of the patients with missed abortion and in normal pregnancy in the week of 20th gestational week and will send to Biochemistry laboratory to examine procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values in their sera. The age, weight, gestational week, gravida (number), parity (number), abortus (number), body mass index, systemic diseases, blood group, smoking information, binary test results, and results of genetic analysis will be collected in both groups. The pathology results of the missed abortion group will also be collected. The results will statistically be compared in the SPSS 13.0 program in both groups.
Interventions
procalcitonin, sedimentation, CRP, leukocyte identification
Sponsors
Study design
Eligibility
Inclusion criteria
* fertile, less than 20 weeks of geese who have missed abortus for the first time without systemic disease
Exclusion criteria
* Failure to meet the missed abortus diagnostic criteria (for the group of fertile missed abortus) * Smoking * Rejection to participate in the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Serum LC | 01.01.2018- 15.02.2019 | Serum leukocyte count in number |
| CRP | 01.01.2018- 15.02.2019 | Serum CRP level in microgram |
| ESR | 01.01.2018- 15.02.2019 | Erythrocyte sedimentation rate |
| Prokalsitonin | 01.01.2018- 15.02.2019 | Serum procalcitonin level in microgram |
Countries
Turkey (Türkiye)