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Research of Serum Procalcitonin, ESR, CRP And Leukocyte Levels in Fertile Missed Abortion Cases

Research of Serum Procalcitonin, Erythrocyte Sedimentation Rate, C-Reactive Protein And Leukocyte Levels in Fertile Missed Abortion Cases

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03767179
Enrollment
60
Registered
2018-12-06
Start date
2018-01-01
Completion date
2018-05-15
Last updated
2020-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abortion, Missed

Keywords

Missed abortion, Procalcitonin, Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), Leukocyte (WBC)

Brief summary

Aim: The serum procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values will be compared between fertile missed abortion diagnosed pregnants and fertile normal pregnants to determine the presence of subclinical infection in the etiology of missed abortion

Detailed description

The study group will consist of 30 fertile, under 35 years old women having for the first time missed abortus diagnosis in the Obstetrics Department of Obstetrics and Gynecology of Medicine Faculty of Karadeniz Technical University, Medical Faculty of Medicine. As control group, 30 cases with the same trimester, fertile, and under 35 years old who had referred to Obstetrics clinic, who had no systemic disease, will be included in the study. Blood samples will be collected at the time of diagnosis of the patients with missed abortion and in normal pregnancy in the week of 20th gestational week and will send to Biochemistry laboratory to examine procalcitonin, erythrocyte sedimentation rate, c-reactive protein and leukocyte values in their sera. The age, weight, gestational week, gravida (number), parity (number), abortus (number), body mass index, systemic diseases, blood group, smoking information, binary test results, and results of genetic analysis will be collected in both groups. The pathology results of the missed abortion group will also be collected. The results will statistically be compared in the SPSS 13.0 program in both groups.

Interventions

DIAGNOSTIC_TESTstudy

procalcitonin, sedimentation, CRP, leukocyte identification

Sponsors

Karadeniz Technical University
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* fertile, less than 20 weeks of geese who have missed abortus for the first time without systemic disease

Exclusion criteria

* Failure to meet the missed abortus diagnostic criteria (for the group of fertile missed abortus) * Smoking * Rejection to participate in the study.

Design outcomes

Primary

MeasureTime frameDescription
Serum LC01.01.2018- 15.02.2019Serum leukocyte count in number
CRP01.01.2018- 15.02.2019Serum CRP level in microgram
ESR01.01.2018- 15.02.2019Erythrocyte sedimentation rate
Prokalsitonin01.01.2018- 15.02.2019Serum procalcitonin level in microgram

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026