Liver Cancer, Liver Diseases
Conditions
Keywords
LiverVision, Liver, Volumetry, Semi-automated, Living donor liver transplantation, Surgery
Brief summary
The LiverVision® software was designed to provide three-dimensional (3D) visualisation of the liver using Computed Tomography (CT) scans. It provides semi-automated volumetry measurements, vascular structure and territory tools.
Detailed description
Liver volumetry has been widely used in liver surgery and living donor liver transplantation to estimate the future liver remnant or the required liver volume for the recipient, respectively. Liver volumetry is typically performed using CT imaging with specially designed software. Such manual measurements are time consuming and there is an ongoing debate whether the they reflect the actual liver volume when performed by radiologists or surgeons as well as according to the different software currently available in the market.
Interventions
DIAGNOSTIC_TESTLiver volumetry of the graft on CT
Preoperative liver volumetry using the CT images of the potential living liver donors.
Sponsors
Ankara University
University Hospital Tuebingen
Imperial College Healthcare NHS Trust
Royal Free Hospital NHS Foundation Trust
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adults (18 years or older) * Living liver donors.
Exclusion criteria
* Recipients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Accuracy of the LiverVision® software volumetric measurements | Baseline (CT performed prior to donation). | Accuracy of the LiverVision® software volumetric measurements assessed by correlation and agreement statistics with the manual volumetric measurements as well as the actual graph weight (reference standard). |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Learning curve of the raters | Baseline (CT performed prior to donation). | Assessment of the learning curve of the raters when using LiverVision® software assessed by the time required for the volumetric measurements and the accuracy of the results. |
| Certainty and accuracy of the volumetric measurements. | Baseline (CT performed prior to donation). | Correlation of the degree of certainty of the raters with the accuracy of their volumetric measurements. |
| Comparison | Baseline (CT performed prior to donation). | Comparison of the accuracy among junior, senior, surgeons and radiologists (4 groups) |
Countries
Germany, Turkey (Türkiye), United Kingdom
Contacts
Primary ContactDimitri A Raptis, MD, MSc, PhD
Backup ContactMassimo Malago', MD, PhD
Outcome results
None listed