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Effects of Respiratory Exercises in Patients With Hemiplegia

Correlation of Pulmonary Function Test and Ultrasonographic Diaphragm Measurements in Patients With Hemiplegia and Investigation of the Effects of Respiratory Exercises on These Parameters

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03763019
Enrollment
40
Registered
2018-12-04
Start date
2019-05-01
Completion date
2020-02-01
Last updated
2020-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemiplegia, Respiratory Abnormality

Keywords

hemiplegia, respiratory function tests, respiratory exercises, diaphragm ultrasonography

Brief summary

This study evaluates the effects of respiratory exercises on respiratory function test parameters and ultrasonographic diaphragmatic measurements. Half of the hemiplegic patients will receive respiratory and neurophysiological exercises, while other half will receive only neurophysiological exercises.

Detailed description

After stroke, diaphragm, the most important muscle of respiration, is wasted as well as the other muscles of the affected side. Ultrasonography is a non-invasive, practical, low cost utility that may measure the thickness of diaphragm in maximum expiration and inspiration thus examining the functionality of the muscle. Correlation between respiratory functional tests and diaphragm ultrasonography has been proven in recent literature. In this manner, the aim of this study is twofold. First is to determine whether ultrasonography can be used practically to evaluate the respiratory functions of the patients after stroke. Respiratory function tests will be used for the correlation analysis. Second is to evaluate the effectiveness of respiratory exercises via diaphragm ultrasonography and respiratory function tests.

Interventions

PROCEDUREConventional rehabilitation

Static and dynamic control of position, balance skills, weight shift, and activities of daily living.

Forced expiration, forced inspiration (thoracal expansion exercise), coughing exercise, incentive spirometric trainer, diaphragmatic respiration exercise, autogenic drainage, percussion.

Sponsors

Bezmialem Vakif University
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SCREENING
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

* Stroke confirmed radiologically * Unilateral hemiplegia * First stroke episode * Mini Mental score ≥ 24

Exclusion criteria

* Unable to consent and understand * Chronic cardiac disease * Pulmonary disease (asthma, restrictive or obstructive pulmonary disease) * Facial paralysis * History of thoracic or abdominal surgery * Being alcoholic * Using psychotropic drugs

Design outcomes

Primary

MeasureTime frameDescription
Tiffeneau-Pinelli index6 weeksA calculated ratio used in the diagnosis of obstructive and restrictive lung disease. Calculated as FEV1/FVC. \>80% is normal. ≤80% indicates an obstructive pulmonary disease.
Forced vital capacity (FVC)6 weeksThe amount of air that can be forcibly exhaled from the lungs after taking the deepest breath possible. Measured by spirometry. \>80% is normal. If the value is lower than the normal limit it indicates either an obstructive or restrictive disease. The lower values show a poorer outcome
Forced expiratory volume in one second (FEV1)6 weeksThe maximal amount of air you can forcefully exhale in one second. Measured by spirometry. \>80% is normal. If there is an obstruction, this measurement shows the severity of the obstruciton. The lower values show a poorer outcome.
Forced expiratory flow at 25% and 75% (FEF 25-75%)6 weeksThe average forced expiratory flow during the mid (25% - 75%) portion of the FVC. Shows small and medium airway obstruction. \>70% is normal. It shows the small airways impariment
Diaphragmatic thickening fraction (TF)6 weeksThickness of the diaphragm is measured from the zone of apposition (subcostal area between anterior axillary line and mid-axillary line) via ultrasonography. After diaphragm thickness in end expiration (thickness in functional residual capacity- TFRC) and in end inspiration (thickness in total lung capacity- TTLC) are obtained. Thickening fraction is calculated as \[TTLC-TFRC/TFRC\]x100. A higher value shows a better outcome.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026