Leukemia
Conditions
Brief summary
hAECs Are Preliminarily Applied in Allogeneic Hematopoietic Stem Cell Transplantation
Detailed description
Establishment of Clinical Applicable Human Amniotic Epithelial Cell Products and Its Preliminary Application in Allogeneic Hematopoietic Stem Cell Transplantation
Interventions
None listed
Sponsors
Shanghai iCELL Biotechnology Co., Ltd, Shanghai, China
Peking University People's Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* leukemia patients with allogeneic HSCT * KFS score \>90 * after transplantation, the patient was implanted (peripheral blood neutrophil absolute value \>500/ul for 3 consecutive days) * no uncontrolled infection after transplantation * activity II above aGVHD * patients agreed to participate in the study
Exclusion criteria
* patients refused to participate in the study * patients have poor compliance * has received hormone therapy * patients had serious heart, lung, liver, kidney and other vital organs damage * researchers believe that patients who are not suitable for observation study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cell counts of T cells, NK cells, B cells and monocytes | Day 7 | proliferation and apoptosis of T cells, NK cells, B cells and monocytes in peripheral blood of patients |
Countries
China
Contacts
Primary Contactxiangyu Zhao
Outcome results
None listed