Anastomotic Leak, Surgical Site Infection
Conditions
Brief summary
The investigators perform a case-control study to compare preparation before elective colorectal surgery. The first group is a prospective patient - registry in all patients with mechanical bowel preparation (MBP) and oral antibiotic prophylaxis the day before colorectal surgery. The second group is a historic collective of patients with MBP only and colorectal surgery. The cases were matches in American Society of Anesthesiologists (ASA) physical status classification system, BMI, operative procedure and risk factors.
Interventions
DRUGParomomycin Sulfate Powder
The patients receive Paromomycin and Metronidazole the day prior to colorectal surgery after mechanical bowel preparation
Sponsors
University of Leipzig
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* all colorectal resections
Exclusion criteria
* allergy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Surgical Site Infections | 30 days (exact 30 days after the Operation date) | Any kind of surgical site infection in the postoperative course. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Anastomotic Leak | 30 days (exact 30 days after the Operation date) | All with objective methods proven anastomotic leakage (like contrast enema, re-operation or endoscopy) |
Countries
Germany
Contacts
Backup ContactInes Gockel, Prof. Dr.
Primary ContactBoris Jansen-Winkeln, PD Dr.
Outcome results
None listed