Parkinson Disease
Conditions
Brief summary
Parkinson's disease is a progressive, degenerative neurological disease associated with profound changes in the quality of life of its survivors. Recent evidence has demonstrated the potential use of transcranial direct current stimulation (tDCS) to modulate cerebral excitability and movement control in neurological chronic conditions. However, few studies have investigated the effects of tDCS on postural control in patients with Parkinson's disease. This study aims to investigate the effect of bihemispheric tDCS on postural control in people with Parkinson's disease. Participants will be randomized to receive a single session of anodal and sham bihemispheric tDCS (7 days between each type of stimulation). Primary clinical outcome (balance) will be collected before and immediately after tDCS. The data will be collected by a blind examiner to the treatment allocation.
Interventions
PROCEDURETranscranial direct current stimulation
Transcranial direct current stimulation is a noninvasive technique of neuronal modulation that has been used in different chronic neurological conditions, including Parkinson's disease.
Sponsors
Universidade Federal do Piauí
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
40 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
Medical diagnosis of idiopathic Parkinson's disease present for at least 12 months In clinical follow-up and pharmacological treatment by a responsible physician Parkinson's classification of 1.5-3 according to the Hoehn and Yahr scale Signing of the free and informed consent form-
Exclusion criteria
Use any associated orthopedic device to aid gait or balance control Signs of severe dementia (evaluated by the Mini-Mental State Examination - MMSE) Diagnosis of other neurological disorders (including those of central and peripheral nature) Previous treatment with tDCS Medical diagnosis of psychiatric illnesses with the use of centrally acting medications (depressants) The use of pacemakers or other implanted devices.-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from COP - area | Baseline and Post-tDCS (immediately after tDCS) | Postural instability will be evaluated using a force plate to record center of pressure displacement (COP) area (cm²). |
| Change from COP - AP axis | Baseline and Post-tDCS (immediately after tDCS) | Postural instability will be evaluated using a force plate to record center of pressure displacement (COP) in antero-posterior (AP) axis in centimeters. |
| Change from COP - ML axis | Baseline and Post-tDCS (immediately after tDCS) | Postural instability will be evaluated using a force plate to record center of pressure displacement (COP) in Mediolateral (ML) axis in centimeters. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Adverse effects | Immediately after tDCS | Adverse effects will be evaluated using structured questionnaire |
Countries
Brazil
Outcome results
None listed