Bariatric Surgery
Conditions
Keywords
bariatric surgery, volume-controlled ventilation, pressure-controlled ventilation
Brief summary
The purpose of this study is to compare volume controlled-ventilation (VCV) and pressure-controlled ventilation (PCV) in terms of pulmonary gas exchange, respiratory mechanics and arterial blood gas values in patients undergoing laparoscopic bariatric surgery.
Detailed description
Today, morbid obesity has become a global problem. It is not clear which mechanical ventilation mode will be used in bariatric surgery, which is one of the treatment options of these patients. VCV is the most commonly used mode to ventilate anesthetized patients. However, especially in obese patients, high airway pressures and hypoxia may occur due to increased intrapulmonary shunts. Therefore, we aimed to investigate the potential of PCV strategy to improve pulmonary gas exchange, respiratory mechanics and arterial blood gas values according to VCV in patients undergoing bariatric surgery.
Interventions
PROCEDUREvolume-controlled ventilation
PROCEDUREpressure-controlled ventilation
Sponsors
Antalya Training and Research Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* 18 years or above, * ASA II patients * BMI \> 40 kg / m2 * No serious comorbidity.
Exclusion criteria
* Unstable patients during the operation * The requirement for mechanical ventilation in the postoperative period.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Partial oxygen pressure | 5 minutes after induction | Assessed 5 minutes after induction by using arterial blood gas analysis. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Partial carbon dioxide pressure - end-tidal carbon dioxide pressure | 5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes | Assessed 5 minutes after induction, 30 minutes after pneumoperitoneum and through surgery completion, an average of 90 minutes by using arterial blood gas analysis and end-tidal monitor. |
| Peak airway pressure | 5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes | Assessed 5 minutes after induction, 30 minutes after pneumoperitoneum and through surgery completion, an average of 90 minutes by using the patient monitor. |
| Partial carbon dioxide pressure | 5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes | Assessed 5 minutes after induction, 30 minutes after pneumoperitoneum and through surgery completion, an average of 90 minutes by using arterial blood gas analysis. |
| Inspired oxygen pressure / Fractional oxygen ratio | 5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes | Assessed 5 minutes after induction, 30 minutes after pneumoperitoneum and through surgery completion, an average of 90 minutes |
| Alveolar-arterial oxygen gradient pressure | 5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes | Assessed 5 minutes after induction, 30 minutes after pneumoperitoneum and through surgery completion, an average of 90 minutes by using formula (D(A-a) O2). |
| Dynamic compliance | 5 minutes after induction, 30 minutes after pneumoperitoneum, through surgery completion, an average of 90 minutes | Assessed 5 minutes after induction, 30 minutes after pneumoperitoneum and through surgery completion, an average of 90 minutes by using formula (Tidal volume/peak airway pressure - Positive end-expiratory pressure) |
Countries
Turkey (Türkiye)
Outcome results
None listed