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CLARITY Imaging Study

CLARITY Imaging Study: The Effect Of Cross-linked Sodium Hyaluronate On The Quality Of Optical Coherence Tomography Imaging

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03758859
Acronym
CLARITY
Enrollment
80
Registered
2018-11-29
Start date
2019-04-12
Completion date
2019-10-31
Last updated
2019-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Keywords

Glaucoma

Brief summary

OCT image quality is necessary to provide accurate diagnostic information to ophthalmologists. The increasing resolution of imaging techniques will require ever more high standards of optical transmission through the cornea and tear film. Given that lubricant drops can improve optical transmission through the cornea, this study will attempt to quantify this. The primary objective is to assess the effect of cross-linked sodium hyaluronate on OCT image quality compared to the effect of blinking alone.

Interventions

OTHERsodium hyaluronate eyedrops

sodium hyaluronate eyedrops administered - route ocular -topical

Sponsors

Imperial College London
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE

Masking description

Randomisation is between eyes i.e. eye exposed to blinking alone vs eye exposed to lubricant drops

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients subjectively deemed to have poor image quality by the photographer

Exclusion criteria

* Patients with a known adverse reaction to any of the constituents of the XLHA * Patients wearing contact lenses * Patients who have used eyedrops in the past 2 hours

Design outcomes

Primary

MeasureTime frameDescription
Clarity of retinal images obtained by Optical Coherence Tomography.immediately after the administration of drops.Signal strength of OCT scan

Countries

United Kingdom

Contacts

Primary ContactSerge Miodragovic
serge.miodragovic1@nhs.net+442033123206
Backup ContactTimothy Yap
timothyedward.yap@nhs.net+442033123206

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026