Skip to content

Mechanisms of Fall Resistance to Diverse Slipping Conditions

Mechanisms of Fall Resistance to Diverse Slipping Conditions

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03758040
Enrollment
43
Registered
2018-11-29
Start date
2019-12-15
Completion date
2021-11-16
Last updated
2025-07-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Slipping and Falls

Brief summary

Falls are the leading source of injury for all ages, and for older adults are the primary cause of injury related death. Loss of foot to ground traction accounts for 25-40% of falls, typically referred to as a slip. Slips alter the relationship between center of mass and lower limb base of support resulting in altered whole-body angular momentum and inability to support body weight due to loss of stability. But not all slips lead to falls. Stability may be recovered through a combination of response movements, such as swinging the arms or rapid recovery steps. Stability must be recovered quickly otherwise insufficient bodyweight support rapidly leads to a damaging ground collision. A high percentage of falls result in fractures, contusions and sprains to both the trunk and limbs, while slips disproportionately cause lower back injuries. A primary goal of fall prevention training is to improve the ability to resist slips using perturbations that mimic the specific sensory and biomechanical context of natural slip events. However, generating lifelike slip perturbations that mimic the diversity of slipping conditions poses a significant hurdle to improving a more general slip resistance ability. Using movement analysis, the investigators will determine the relationships between diverse slip conditions, reactive responses to slips from those conditions, and slip vulnerability across the gait cycle to generate new data that may guide future interventions.

Detailed description

Recent evidence suggests most slip-related falls in daily life happen in diverse slipping conditions where the ground is not level, or the person is turning or changing direction. While slips that occur during straight walking on level ground and the responses to those slips are relatively well understood, very little is known about slips that occur while walking on slopes or curved paths and which reactive responses are effective to prevent falls in such conditions. This limits the ability of clinicians to incorporate a diverse range of slipping experiences into fall prevention interventions. Understanding how reactive responses and slip vulnerability depend on diverse slip conditions may guide future interventions that promote a more general fall resistance to the broader range of slips encountered in the real environment. This project will determine the impact of turns and slopes on reactive movements and fall vulnerability by determining the effects of path curvature on reactive movements and slip vulnerability at different times in the gait cycle and determining the effects of ground slope on reactive movements and slip vulnerability at difference times in the gait cycle. It is hypothesized that diverse slipping conditions will change the reactive responses involving protective stepping and arm swing and that the distinct dynamics of turns and slopes produce maximum vulnerability to slips at different times in the gait cycle compared to slips during straight walking on level ground. To evaluate these aims, the investigators will administer slip perturbations on slopes that vary in both magnitude and direction, on curved paths that vary in curvature, and with slip onset that varies across early, middle, and late stance. Understanding the relationships between diverse slipping conditions, reactive responses, slip severity and fall vulnerability may guide future research and training interventions towards more comprehensive fall resistance ability.

Interventions

OTHERSlips on Turns

A slip will be administered to participants at 3 different times in the gait cycle for each of 3 different patch curvatures and 2 different legs for a total of 18 slip episodes. Slips will be delivered while walking along a straight path (infinite radius), or curved paths with radii 2, or 1 meters.

OTHERSlips on Slopes

Slips will be administered to participants at 3 different times in the gait cycle over sloped ground surface of no slope, ±5.0 and ±10.0 degrees slopes in the direction of walking, and 5.0 and 10.0 degrees perpendicular to the direction of walking. On slopes perpendicular to the direction of walking, slips will be administered to the uphill or downhill foot. A total of 27 slip episodes will be administered. Sloped walking surfaces will be generated with the Computer Assisted Rehabilitation Environment (CAREN) system treadmill.

Sponsors

National Institute on Aging (NIA)
CollaboratorNIH
University of Nebraska
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
19 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Age 19-35

Exclusion criteria

* Uncontrolled hypertension * Peripheral arterial disease * Knee osteoarthritis * Vertigo * Meniere's disease * Chronic dizziness * History of back or lower extremity injury * Surgery that affects mobility * Neurological disease that limits the ability to walk

Design outcomes

Primary

MeasureTime frameDescription
Fall Rates - Slips on TurnsUp to 4 hoursPercentage of trials which result in a fall is recorded. Falls are classified when a load cell embedded in the harness system measures support forces exceeding 30% body weight.
Fall Rates - Slips on SlopesUp to 4 hoursPercentage of trials which result in a fall is recorded. Falls are classified when a load cell embedded in the harness system measures support forces exceeding 30% body weight.

Secondary

MeasureTime frameDescription
Trunk Maximum Angular MomentumUp to 4 hoursThe maximum angular momentum of the trunk following the administered slip perturbation
Reactive Stepping Response PlacementUp to 4 hoursPosition of the placement of the reactive stepping response relative to the center of mass following the administered slip perturbation
Slipping Foot DistanceUp to 4 hoursThe distance travelled by the slipping foot relative to the center of mass following the administered slip perturbation
Reactive Arm Swing Momentum ChangeUp to 4 hoursThe change in arm momentum between the onset of the administered slip perturbation and the end of the slip
Reactive Stepping Response TimeUp to 4 hoursDuration of time between the onset of the administered slip perturbation and the placement of the reactive stepping response
Slipping Foot Maximum VelocityUp to 4 hoursThe maximum velocity of the slipping foot relative to the center of mass following the administered slip perturbation

Countries

United States

Participant flow

Participants by arm

ArmCount
Slips on Turns
Slips administered during walking on a straight path, or on curved paths of radii 1.0, or 2.0 meters in early, middle or late stance to the inside or outside foot. Slips on Turns: Subjects were administered a slip at 3 different times in the gait cycle for each of 3 different patch curvatures and 2 different legs for a total of 18 slip episodes. Slips were delivered while walking along a straight path (infinite radius), or curved paths with radii 2, or 1 meters.
21
Slips on Slopes
Slips administered during walking on sloped ground of 5.0 or 10.0 degrees mediolaterally or anteroposteriorly, or flat ground, in early middle or late stance. For mediolateral slopes, slips were administered to the uphill or downhill foot. Slips on Slopes: Slips were administered at 3 different times in the gait cycle over sloped ground surface of no slope, ±5.0 and ±10.0 degrees slopes in the direction of walking, and 5.0 and 10.0 degrees perpendicular to the direction of walking. On slopes perpendicular to the direction of walking, slips will be administered to the uphill or downhill foot. A total of 27 slip episodes will be administered. Sloped walking surfaces will be generated with the CAREN system treadmill.
21
Total42

Baseline characteristics

CharacteristicSlips on TurnsTotalSlips on Slopes
Age, Categorical
<=18 years
0 Participants0 Participants0 Participants
Age, Categorical
>=65 years
0 Participants0 Participants0 Participants
Age, Categorical
Between 18 and 65 years
21 Participants42 Participants21 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
2 Participants2 Participants0 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
19 Participants40 Participants21 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants0 Participants0 Participants
Height1.72 meters
STANDARD_DEVIATION 0.12
1.72 meters
STANDARD_DEVIATION 0.1
1.73 meters
STANDARD_DEVIATION 0.08
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants0 Participants0 Participants
Race (NIH/OMB)
Asian
4 Participants7 Participants3 Participants
Race (NIH/OMB)
Black or African American
2 Participants3 Participants1 Participants
Race (NIH/OMB)
More than one race
0 Participants0 Participants0 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants0 Participants0 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants0 Participants0 Participants
Race (NIH/OMB)
White
15 Participants32 Participants17 Participants
Sex: Female, Male
Female
10 Participants20 Participants10 Participants
Sex: Female, Male
Male
11 Participants22 Participants11 Participants
Weight71.72 kilograms
STANDARD_DEVIATION 18.17
72.36 kilograms
STANDARD_DEVIATION 15.26
72.90 kilograms
STANDARD_DEVIATION 12.8

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
deaths
Total, all-cause mortality
0 / 210 / 21
other
Total, other adverse events
0 / 210 / 21
serious
Total, serious adverse events
0 / 210 / 21

Outcome results

Primary

Fall Rates - Slips on Slopes

Percentage of trials which result in a fall is recorded. Falls are classified when a load cell embedded in the harness system measures support forces exceeding 30% body weight.

Time frame: Up to 4 hours

Population: Slips were administered at 3 different times in the gait cycle over sloped ground surface of no slope, ±5.0 and ±10.0 degrees slopes in the direction of walking, and 5.0 and 10.0 degrees perpendicular to the direction of walking. On slopes perpendicular to the direction of walking, slips will be administered to the uphill or downhill foot. A total of 27 slip episodes will be administered. Sloped walking surfaces will be generated with the CAREN system treadmill.

ArmMeasureGroupValue (NUMBER)
Slips on TurnsFall Rates - Slips on SlopesFall Rate, Level Walking6.35 Percent of trials resulting in falls.
Slips on TurnsFall Rates - Slips on SlopesFall Rate, Sloped Walking (5 degrees), Uphill Slope6.35 Percent of trials resulting in falls.
Slips on TurnsFall Rates - Slips on SlopesFall Rate, Sloped Walking (10 degrees), Uphill Slope50.79 Percent of trials resulting in falls.
Slips on TurnsFall Rates - Slips on SlopesFall Rate, Sloped Walking (5 degrees), Downhill Slope7.94 Percent of trials resulting in falls.
Slips on TurnsFall Rates - Slips on SlopesFall Rate, Sloped Walking (10 degrees), Downhill Slope44.44 Percent of trials resulting in falls.
Slips on TurnsFall Rates - Slips on SlopesFall Rate, Sloped Walking (5 degrees), Cross-Slope9.60 Percent of trials resulting in falls.
Slips on TurnsFall Rates - Slips on SlopesFall Rate, Sloped Walking (10 degrees), Cross-Slope44.00 Percent of trials resulting in falls.
Primary

Fall Rates - Slips on Turns

Percentage of trials which result in a fall is recorded. Falls are classified when a load cell embedded in the harness system measures support forces exceeding 30% body weight.

Time frame: Up to 4 hours

Population: Subjects were administered a slip at 3 different times in the gait cycle for each of 3 different patch curvatures and 2 different legs for a total of 18 slip episodes. Slips were delivered while walking along a straight path (infinite radius), or curved paths with radii 2, or 1 meters.

ArmMeasureGroupValue (NUMBER)
Slips on TurnsFall Rates - Slips on TurnsFall Rate, Straight Walking0 Percent of trials resulting in falls.
Slips on TurnsFall Rates - Slips on TurnsFall Rate, Curved Walking (2 meter radius), slip administered to the inside foot7.94 Percent of trials resulting in falls.
Slips on TurnsFall Rates - Slips on TurnsFall Rate, Curved Walking (2 meter radius), slip administered to the outside foot1.59 Percent of trials resulting in falls.
Slips on TurnsFall Rates - Slips on TurnsFall Rate, Curved Walking (1 meter radius), slip administered to the inside foot23.44 Percent of trials resulting in falls.
Slips on TurnsFall Rates - Slips on TurnsFall Rate, Curved Walking (1 meter radius), slip administered to the outside foot3.13 Percent of trials resulting in falls.
Secondary

Reactive Arm Swing Momentum Change

The change in arm momentum between the onset of the administered slip perturbation and the end of the slip

Time frame: Up to 4 hours

Secondary

Reactive Stepping Response Placement

Position of the placement of the reactive stepping response relative to the center of mass following the administered slip perturbation

Time frame: Up to 4 hours

Secondary

Reactive Stepping Response Time

Duration of time between the onset of the administered slip perturbation and the placement of the reactive stepping response

Time frame: Up to 4 hours

Secondary

Slipping Foot Distance

The distance travelled by the slipping foot relative to the center of mass following the administered slip perturbation

Time frame: Up to 4 hours

Secondary

Slipping Foot Maximum Velocity

The maximum velocity of the slipping foot relative to the center of mass following the administered slip perturbation

Time frame: Up to 4 hours

Secondary

Trunk Maximum Angular Momentum

The maximum angular momentum of the trunk following the administered slip perturbation

Time frame: Up to 4 hours

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026