Does the Embryo Transfer Technique Affect the Success of in Vitro Fertilization?

Comparison of IVF Success Rates Between Different Embryo Transfer Techniques: Afterload Technique and Trial Followed by Transfer Technique

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03756857

Enrollment

200

Registered

2018-11-28

Start date

2019-01-21

Completion date

2021-12-31

Last updated

2021-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Assisted Reproductive Technology, Infertility, IVF

Brief summary

Prospective, open, randomized, parallel, two-arm trial to compare the clinical pregnancy rate between most commonly used two embryo transfer techniques: trial followed by transfer technique and afterloading technique

Detailed description

Eligible patients will be informed about the possibility of participating in the clinical trial in the beginning of treatment and on the day ET, a signed consent form will be collected from those recipients who confirmed their participation. These patients will be randomized immediately before the ET procedure by sequentially numbered, opaque, sealed envelopes

Interventions

PROCEDUREAfterload Transfer

Embryo transfer is done by using afterload transfer method

PROCEDURETrial followed by transfer

Embryo transfer is done by using afterload transfer method

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Intervention model description

Prospective, open, randomized, parallel, two-arm trial

Eligibility

Sex/Gender

FEMALE

Age

20 Years to 37 Years

Healthy volunteers

Yes

Inclusion criteria

1. Patient has given written informed consent 2. BMI 18-30 kg/m2 3. \< 2 previous failed IVF trials 4. At least two good quality embryos on the day of transfer

Exclusion criteria

1. Congenital uterine anomaly 2. Untreated endometrial polyp or fibroid distorting uterine cavity 3. Presence of hydrosalpinx 4.2 or more prior IVF trial failure 5.Moderate to severe endometriosis 6.Recurrent pregnancy loss history

Design outcomes

Primary

Measure	Time frame	Description
clinical pregnancy rate	5-6 weeks after embryo transfer	the presence of gestational sac on ultrasound

Secondary

Measure	Time frame	Description
implantation rate	3-4 weeks after embryo transfer	the number of gestational sacs divided by the number of embryos transferred

Countries

Turkey (Türkiye)

Contacts

Primary ContactElif Esra UYAR, MD

esra.uyar@acibadem.com+902166494444

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026