The Critical Threshold of Pulse Oximetry Plethysmographic Waveform Parameters in High Quality CPR

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03754946

Enrollment

1000

Registered

2018-11-27

Start date

2015-09-01

Completion date

2018-12-31

Last updated

2018-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiopulmonary Resuscitation

Keywords

cardiopulmonary resuscitation, pulse oximetry plethysmographic waveform, quality monitor, partial pressure of end-tidal carbon dioxide

Brief summary

The purpose of this study is to analyze the relationship of the area under the curve (AUC) and/or the amplitude (Amp) of pulse oximetry plethysmographic waveform (POP) with partial pressure of end-tidal carbon dioxide (PETCO2) which could be used to reflect its quality in cardiopulmonary resuscitation (CPR), and then to determine the critical threshold of POP parameters in high quality CPR.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* Cardiac arrested * The time from cardiac arrest to receiving basic life support is less than 10 minutes * Get advanced life support (endotracheal intubation and PETCO2 monitoring)

Exclusion criteria

* Defuse CPR * chronic obstructive pulmonary disease (COPD) with type II respiratory failure * Terminal malignant tumors or terminal stage of other diseases * Rib fracture * Cardiac arrest caused by hemorrhagic shock pulmonary embolism and cardiac tamponade * Sever anemia(HGB\<7g/dl) * Untreated tension pneumothorax * Tinea unguium, dyeing Fingernails and other factors affect the monitor of Pulse Oximetry Plethysmographic Waveform such vasculitis and Raynaud's phenomenon

Design outcomes

Primary

Measure	Time frame	Description
the cut-off value of POP parameters in High Quality CPR	one year	Describe the the cut-off value of POP parameters in High Quality CPR. Receiver operating curve analysis was performed to evaluate the accuracy in predicting return of spontaneous circulation (ROSC).
Compare different predictors	one year	Area under curve (AUC) between potential predictors was compared by using a nonparametric test, and the optimal cutoff point was determined by estimating the Youden's index.

Countries

China

Contacts

Primary ContactXuezhong Yu, MD

yxzpumch@126.com+86 010 69159142

Outcome results