Anesthesia, Local
Conditions
Keywords
Peripheral nerve block
Brief summary
Regional tissue oxygenation saturation has been shown to increase in innervated regions after sympathetic block. The aim of this prospective observational study was to evaluate the changes of regional tissue oxygenation saturation by near-infrared spectroscopy after successful femoral nerve block with ropivacaine and determine whether the changes of regional tissue oxygenation saturation can be affected by the concentration of ropivacaine.
Detailed description
Successful peripheral nerve blocks induce sympathetic blockade, which increases local blood flow by vasodilation. The relationship between successful femoral nerve block and the variation of regional tissue oxygenation saturation was unclear.
Interventions
DEVICEtissue oxygenation saturation
tissue oxygenation saturation
Sponsors
Huazhong University of Science and Technology
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
* Informed consent * American Society of Anesthesiologists physical statusⅠ-Ⅱ * Undergo elective elective knee arthroscopy with peripheral nerve block
Exclusion criteria
* Refusal to participate in the study * BMI\>35 * Any contraindications to peripheral nerve block such as coagulation abnormalities, •Allergy to local anaesthetics, peripheral neuropathy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Regional tissue oxygenation saturation after successful femoral nerve block | at 5-minute intervals till 30 minutes after regional block | rSO2 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pinprick sensory scores | 5 minute before regional block and at 5-minute intervals till 30 minutes after regional block | A 3-level scale was used to grade the intensity of sensory block using pinprick stimulation: 0=normal sensation; 1=analgesia; 2=anesthesia. |
Countries
China
Outcome results
None listed