Identification of Respiratory Profiles From Nasal Pressure Signals

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03753386

Acronym

IPR-SAINS

Enrollment

Registered

2018-11-27

Start date

2019-05-16

Completion date

2019-05-28

Last updated

2019-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Brief summary

Chronic Obstructive Pulmonary Disease (COPD) is a chronic respiratory disease caused by smoking and associated with significant morbidity due to recurrent exacerbations or even hospitalizations. It is one of the leading causes of death in rich countries. Early detection of exacerbations of the disease is thus an economic and public health issue in the world. Finding tools for automatic and early detection of an exacerbation is the subject of the study. A continuous analysis of the frequency and shape of the patients' breathing will be used. As a first step in this study, investigators want to measure the frequency and shape of breathing in healthy subjects as they execute standard activities. These activities include resting, drinking, coughing, speaking, breathing through the mouth, physical exercise and recuperation.

Interventions

OTHEROxygen therapy simulation

The intervention consists of reproducing oxygen therapy situations in healthy individuals by replacing oxygen bottles with bottles of air. A TeleOx® device will be placed on the circuit between the source and the nasal cannula for respiratory signals recording. The intervention will last 30 minutes, containing the following activities in the given order: * rest (9 minutes); * drinking water (1 minute); * rest (1 minute); * coughing (1 minute); * rest (1 minute); * reading aloud (1 minute); * rest (1 minute); * breathing by the mouth (1 minute); * rest (1 minute); * exercising (running) (3 minutes) and * rest (10 minutes) Recordings will be retrieved after each test.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* Age of majority * Health volunteers

Exclusion criteria

* Pregnancy * Age of minority * Protected adult * Person deprived of liberty * Respiratory pathology * Non affiliation to the health care system

Design outcomes

Primary

Measure	Time frame	Description
Pressure	10 Hz for 30 minutes	The monitoring device used records the nasal pressure from users at 10 Hz (one measure every 0.1 seconds).

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 22, 2026