Comparison of Two Electroencephalograms (EEG) Monitors in Patients Undergoing General Intravenous Anesthesia

Assessment of the Depth of Anesthesia During Intravenous Anesthesia: Comparison of the Bispectral Index Monitor and the qCON Monitor.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03753217

Acronym

Bis-qCON-IV

Enrollment

Registered

2018-11-26

Start date

2018-12-04

Completion date

2018-12-21

Last updated

2019-02-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General Anesthesia

Keywords

Anesthesia Monitoring

Brief summary

Quantium Medical Company has an ElectroEncephalograph-based (EEG-based) algorithm with two outputs: qCON for unconsciousness and qNOX for anti-nociception. qCON, is designed to provide information about the depth of the hypnotic state, similar to that provided by the BIS™.

Interventions

DEVICEqCON Monitor

supervision by qCON monitor of the depth of anesthesia

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

OTHER

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients above 18 years, * Patients affiliated to a national insurance scheme or benefiting from such a program, * Patients having given their written consent, * Patients that must benefit from a general anesthesia by intravenous drugs (propofol and remifentanil), * For the patients taken care in ambulatory surgery, having a telephone and agreeing to communicate their phone number.

Exclusion criteria

* Pregnant or breast-feeding Women, * Patients having a limit of use of the Bispectral Index (BIS) or qCON monitors, * Patients having a contraindication to Propofol and/or to Remifentanil.

Design outcomes

Primary

Measure	Time frame	Description
qCON monitoring during maintenance of anesthesia	Up to 10 hours	Measurement of qCON values during maintenance of anesthesia
BIS monitoring during maintenance of anesthesia	Up to 10 hours	Measurement of BIS values during maintenance of anesthesia

Secondary

Measure	Time frame	Description
qCON monitoring during recovery of anesthesia	One day	Measurement of qCON values during recovery of anesthesia
BIS monitoring during recovery of anesthesia	One day	Measurement of BIS values during recovery of anesthesia
Burst Suppression ratio retrieved by qCON monitoring	One day	Measurement of Burst Suppression ratio values during anesthesia
Burst Suppression ratio retrieved by BIS monitoring	One day	Measurement of Burst Suppression ratio values during anesthesia
qCON monitoring during induction of anesthesia	One day	Measurement of qCON values during induction of anesthesia
Periods of loss of signal of qCON	One day	Measurement of qCON values during anesthesia
Periods of loss of signal of BIS	One day	Measurement of BIS values during anesthesia
Intraoperative memorising	One day	Questionnaire for assessment of memorising of surgery by the patient
qNOX monitoring during anesthesia	One day	Measurement of qNOX values during anesthesia
BIS monitoring during induction of anesthesia	One day	Measurement of BIS values during induction of anesthesia

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026