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Assessment of Neurosensory Function Following Segmental Mandibular Resection.

Assessment of Neurosensory Function Following Segmental Mandibular Resection of Non-malignant Lesions With Inferior Alveolar Nerve Preservation: A Case Series Trial

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03752554
Enrollment
10
Registered
2018-11-26
Start date
2018-11-15
Completion date
2020-12-30
Last updated
2019-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Resection Cavity

Keywords

segmental mandibular resection-IAN

Brief summary

This study wInclusion criteria for this study will be as follows: * Age group: from 15 to 60 years old. * Patients with with non malignant mandibular neoplasms indicated for segmental resection. Exclusion criteria: * Patients with malignant mandibular neoplasms. All cases will undergo surgery under general anesthesia. The mandibular lesion will be segmentally resected. The cuts will be performed with the aid of the prefabricated digital template. The neurovascular bundle will be separated and protected. Then reconstruction will be performed. Postoperative patient evaluation: Neurosensory examination: Assessment of the inferior alveolar nerve function will be performed preoperatively, 2 and 12 weeks postoperatively through Trigeminal somatosensory evoked potential technique. Six months postoperatively by CBCT for assessment of recurrence

Detailed description

This study will include 10 patients complaining from non malignant mandibular lesions. nopatients will be selected from the outpatient clinic of the Oral & Maxillofacial Surgery department, faculty of Dental Medicine Cairo University. All the procedures will be explained for all patients before undergoing operation and informed consent process will be taken, this study will be displayed to the research ethics committee to obtain approval. Inclusion criteria for this study will be as follows: * Age group: from 15 to 60 years old. * Patients with with non malignant mandibular neoplasms indicated for segmental resection. Exclusion criteria: * Patients with malignant mandibular neoplasms. 1- Pre-operative phase Patients will be subjected to: Case history including personal data, medical, a-surgical and family history b-Clinical examination c.Radiographic examination using orthopantogram, and computed tomography (CT) Preoperative anesthesia assessment for fitness for general anesthesia.d Treatment planning and fabrication of the digital template.e 2 -Operative phase All cases will undergo surgery under general anesthesia. The mandibular lesion will be segmentally resected. The cuts will be performed with the aid of the prefabricated digital template. The neurovascular bundle will be separated and protected. Then reconstruction will be performed. 3-Postoperative care: Postsurgical instructions and follow up: Proper postoperative instructions will be given the patient, in addition to the postoperative medications including antibiotics, corticosteroids and analgesics. Postoperative patient evaluation: Neurosensory examination: Assessment of the inferior alveolar nerve function will be performed preoperatively, 2 and 12 weeks postoperatively through Trigeminal somatosensory evoked potential technique. Six months postoperatively by CBCT for assessment of recurrence. Statistical analysis: Data will be analyzed using IBM SPSS advanced statistics (Statistical Package for Social Sciences), version 21 (SPSS Inc. Chicago). The data will be compared using paired t-test.

Interventions

All cases will undergo surgery under general anesthesia. The mandibular lesion will be segmentally resected. The cuts will be performed with the aid of the prefabricated digital template. The neurovascular bundle will be separated and protected. Then reconstruction will be performed

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
15 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* -Age group: from 15 to 60 years old. * Patients with with non malignant mandibular neoplasms indicated for segmental resection..

Exclusion criteria

* -Patients with malignant mandibular neoplasms

Design outcomes

Primary

MeasureTime frameDescription
measurement of nerve stimulation3 monthssomatosensory evoked potential technique

Countries

Egypt

Contacts

Primary Contactmahmoud mo shalash, researcher
shalash_dentistry@gmail.com01006151498
Backup Contactadel h aboelftoh, ass prof
aabouelfetouh@dentistry.cu.edu.eg01018871899

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026