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Development and Preliminary Trial of a Brief, Portable Health Intervention for Rural Sexual Minority Emerging Adults

Development and Preliminary Trial of a Brief, Portable Health Intervention for Rural Sexual Minority Emerging Adults

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03751020
Acronym
Project LEAP
Enrollment
108
Registered
2018-11-23
Start date
2017-10-27
Completion date
2019-06-27
Last updated
2020-08-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression, HIV, Minority Stress, Substance Abuse, Suicidality

Keywords

Expressive Writing, Minority Stress, Lesbian Gay Bisexual

Brief summary

The purpose of this study is to test the feasibility of writing interventions specifically designed for lesbian, gay, and bisexual (LGB) emerging adults (ages 18-29) that are aimed at improving the outcomes: depression, suicidality, substance abuse and HIV risk behaviors.

Detailed description

This study is considered the third part (Phase 3) of a larger study where parts one and two were designed to utilize elicitation focus groups to develop effective intervention materials (Phase 1) and then refine the developed materials through structured interviews (Phase 2). Phase 3 will test feasibility and assess early signs of efficacy of writing interventions. To do this, participants will be randomized to one of three arms (one arm will serve as control). Those that choose to participate will be asked to complete outcome measures (depressive symptoms, suicidality, use of alcohol and illicit drugs, HIV risk behavior) and measures of proposed mediators (self-reported and biological stress, behavioral and emotional self-regulation) and moderators (e.g., social support, identity centrality) at baseline, post-intervention, and three-month follow-up. In addition, structured interviews with 15 intervention participants will be used to refine study procedures as the investigators scale up this intervention for a future randomized controlled trial (RCT).

Interventions

BEHAVIORALExpressive Writing (EW) Intervention

The EW intervention will utilize the procedures piloted earlier with gay and bisexual male college students in urban and rural regions of the US. In this condition, participants will be instructed to write for 20 minutes across three consecutive days in a free-form manner about the most stressful or traumatic LGB-related event that they have encountered.

BEHAVIORALSelf-Affirmation (SA) Intervention

The SA intervention will ask participants to read a brief description, over the course of 3 consecutive days, of a (hypothetical) LGB youth who is facing minority stress. Each day's description will contain a different LGB youth facing a different stigma-related stressor derived from Phase 1 and 2 interviews. Participants will then be asked to write a letter for 20 minutes to advise the LGB youth how best to cope with minority stress drawing on their personal experiences.

OTHERControl

Participants randomly assigned to the control condition will be asked to write about what they have done since waking up that morning for 20 minutes across 3 consecutive days. This control matches the time and activity of the EW and SA arms and has been implemented across dozens of EW and SA studies.

Sponsors

National Institute of Mental Health (NIMH)
CollaboratorNIH
Yale University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 29 Years
Healthy volunteers
Yes

Inclusion criteria

* Self-identify as lesbian, gay, or bisexual * Live in Washington county, Tennessee (TN), or any of its 6 contiguous counties in northeastern TN * Have personal Internet access * Hair at least 2cm in length

Exclusion criteria

* Failure to meet inclusion criteria

Design outcomes

Primary

MeasureTime frameDescription
Change in Depression.Baseline, Post Intervention (day 5), and 3 Months.Depression will be measured using the Center for Epidemiological Studies -- Depression Scale (CESD). An overall depression score is computed as the sum of 20 items, with items 3, 11, 14, and 16 reversed. In cases with internally missing data (items not answered), the sums are computed after imputation of the missing values: # items on scale / # actually answered, multiplied by the sum obtained from the answered items. A range of 0-60, with higher scores indicating more depressive symptomatology during the past week.
Change in Psychological Distress.Baseline, Post Intervention (day 5), and 3 Months.Psychological Distress will be measured using the Brief Symptom Inventory (BSI). The BSI consists of 18 items scored 0-4. Items are averaged to yield a final score of 0-4. The higher the score, the greater the psychological distress.
Change in Anxiety.Baseline, Post Intervention (day 5), and 3 Months.Anxiety will be measured using the Beck Anxiety Inventory (BAI). The BAI total score is reported, which is the sum of all 21 items; with no subscales. The range of scores is 0-63, with higher scores indicating higher anxiety.
Change in Suicidality - Suicidal Ideation.Baseline, Post Intervention (day 5), and 3 Months.Suicidal ideation will be measured using the Suicidal Ideation Attributes Scale (SIDAS) . Total SIDAS scores are calculated as the sum of the five items, with controllability reverse scored (10=0, 9=1, …, 0=10). Total scores range from 0 to 50.
Change in Alcohol Use.Baseline, Post Intervention, 3 MonthsAlcohol use in participants will be assessed using the Alcohol Use Disorders Identification (AUDIT) instrument. The AUDIT consists of 10 items. Each of the questions has a set of responses to choose from, and each response has a score ranging from 0 to 4. All response scores should be added and recorded as Total. Total scores of 8 or more are recommended as indicators of hazardous and harmful alcohol use, as well as possible alcohol dependence. (A cut-off score of 10 will provide greater specificity but at the expense of sensitivity.) The score range is 0-40. Higher scores indicate greater hazardous drinking.
Change in Drug Use.Baseline, Post Intervention (day 5), and 3 Months.The Short Inventory of Problems-Modified for Drug Use (SIP-DU) is a 15-item scale that asks respondents to rate each item on a dichotomous scale (No = 0, Yes = 1). Total score reported, which is the sum of all items; no subscales: Range 0-15, higher scores indicate greater problems with drug use.
Suicidal IntentBaseline, Post Intervention (day 5), and 3 Months.Suicidal intent will be assessed using a single item that asks: Within the last 3 months/past week, have you seriously considered attempting suicide? \[yes/no\] Number of participants who reported suicidal intent is reported. Originally titled Change in Suicidality - Suicidal Thoughts.
Attempted SuicideBaseline, Post Intervention (day 5), and 3 Months.Suicide attempts will be assessed using a single item that asks: Within the last past 3 months/past week, have you actually attempted suicide? \[yes/no\]. Reported are the number of participants who reported that they had attempted suicide. Original title: Change in Suicidality: Suicide Attempts.

Secondary

MeasureTime frameDescription
Change in Impulsiveness- AttentionalBaseline, Post Intervention (day 5), and 3 Months.Impulsiveness will be assessed using the Barratt Impulsiveness Scale (BIS). The BIS is a 30 item questionnaire that uses a 1-4 rating scale per item. The 30-item self-report questionnaire, can yield a total score, as well as three factors: attentional (6, 5, 9, 11, 20, 24, 26, 28; motor (2, 3, 4, 16, 17, 19, 21, 22, 23, 25, 30); non-planning (1, 7, 8, 10, 12, 13, 14, 15, 18, 27, 29). The attentional scale has a range of 8-32, the greater the value, the greater the level of attentional impulsiveness.
Change in Impulsiveness- MotorBaseline, Post Intervention (day 5), and 3 Months.Impulsiveness will be assessed using the Barratt Impulsiveness Scale (BIS-11). The BIS-11 is a 30 item questionnaire that uses a 1-4 rating scale per item. The 30-item self-report questionnaire, can yield a total score, as well as three factors: attentional (6, 5, 9, 11, 20, 24, 26, 28; motor (2, 3, 4, 16, 17, 19, 21, 22, 23, 25, 30); non-planning (1, 7, 8, 10, 12, 13, 14, 15, 18, 27, 29). The motor scale has a range of 11-44, the greater the value, the greater the level of motor impulsiveness.
Change in Impulsiveness- Non-PlanningBaseline, Post Intervention (day 5), and 3 Months.Impulsiveness will be assessed using the Barratt Impulsiveness Scale (BIS-11). The BIS-11 is a 30 item questionnaire that uses a 1-4 rating scale per item. The 30-item self-report questionnaire, can yield a total score, as well as three factors: attentional (6, 5, 9, 11, 20, 24, 26, 28; motor (2, 3, 4, 16, 17, 19, 21, 22, 23, 25, 30); non-planning (1, 7, 8, 10, 12, 13, 14, 15, 18, 27, 29). The non-planning scale has a range of 11-44, the greater the value, the greater the level of non-planning impulsiveness.
Change in Risk TakingBaseline, Post Intervention (day 5), and 3 Months.Risk taking impulse will be assessed using the Columbia Card Task. Participants are presented with 32 face-down cards. Some of these cards are gain cards (which add either +10 or +30 points to the participant's total score) and some of these cards are loss cards (which subtract either -250 or -750 points from the participant's total score). On each trial, the participant may turn over as many cards as desired until a loss card is encountered or the participant chooses to not turn over any more cards. As a participant turns over more cards, the probability of encountering a loss card increases. Therefore, turning over more cards constitutes greater risk taking.
Change in Minority Stress (Rejection)Baseline, Post Intervention (day 5), and 3 Months.To assess rejection as a form of minority stress, the Gay-Related Rejection Sensitivity Scale (GRRS) will be used.The Gay-related rejection sensitivity scale was adapted for this study to be gender-inclusive and has 12 items. Scale range 1-36, where higher scores indicate greater rejection sensitivity based on one's sexual orientation (worse outcome).
Change in Parental AttitudesBaseline, Post Intervention (day 5), and 3 Months.The participant's perception of their parent's attitudes towards their sexual orientation are assessed using the Parental Attitudes Toward Child's Sexual Orientation. This tool has 4 items- 2 that deal with mother/parent 1/closest female guardian, 2 that deal with father/parent 2/closest male guardian. The second item for each parent asks about their attitude towards the respondent's sexual orientation on a scale from 1 (completely tolerant and accepting) to 7 (completely hostile and rejecting). Scores for maternal and paternal attitude should be averaged for each participant. The score has a range from 1-7, where higher scores indicate greater rejection from parents (worse outcome).
Change in OutnessBaseline, Post Intervention (day 5), and 3 Months.Participants openness about one's sexual orientation will be assessed using the Outness Inventory (OI). A respondent is asked to rate how open they are with various people in society (from family to strangers) on an 11 item questionnaire. The scale for responding is 0-7- where 7 indicates that a person is completely open with their sexual orientation status. The scale score is obtained by averaging the 11 items for a score range of 0-7, where higher scores indicate more openness about respondents' sexual orientation in different domains of their lives/different people. 0 indicates that an item does not apply/ there is no such group of people/person in the respondents' life. A score of 7 would indicate that one is completely open or out with respect to sexual orientation.
Self Injury.Baseline, Post Intervention (day 5), and 3 Months.Self injury behaviors will be assessed with the item that asks: How many times in the past 3 months/past week have you engaged in self-harm behavior (e.g., cutting, biting, burning, hitting self) with the intent of harming, but not killing, yourself? Reported are the frequency of self-harm behaviors/self-injury reported by participants. Original title: Change in Self Injury.
Change in Discrimination - 9 Items (Part 1)Baseline, Post Intervention (day 5), and 3 Months.Everyday discrimination experienced by participants will be measured using the Everyday Discrimination - Sexual Orientation (EDSO) Part 1. Part 1 is a 9 item inventory where respondents rate statements on a scale of 1-6. The scale has a summed total score ranging from 9-54, higher scores indicate higher discrimination. The higher the score, the greater the feeling that one is discriminated against for one's sexual orientation.
Change in Discrimination - Item 1 (Part 2)Baseline, Post Intervention (day 5), and 3 Months.Everyday discrimination experienced by participants will be measured using the Everyday Discrimination - Sexual Orientation (EDSO) Part 2. Part 2 is a 2 item inventory where respondents rate statements on a scale of 0-3. The lower the score, the less the feeling that one is discriminated against overall for one's sexual orientation. Item 1: Overall, how much has discrimination based on your sexual orientation interfered with you having a full and productive life?
Change in Discrimination - Item 2 (Part 2)Baseline, Post Intervention (day 5), and 3 Months.Everyday discrimination experienced by participants will be measured using the Everyday Discrimination - Sexual Orientation (EDSO) Part 2. Part 2 is a 2 item inventory where respondents rate statements on a scale of 0-3. The lower the score, the less the feeling that one is discriminated against overall for one's sexual orientation. Item 2: Overall, how much harder has your life been because of discrimination based on your sexual orientation?
Change in VictimizationBaseline, Post Intervention (day 5), and 3 Months.Feelings of victimization are captured using the LGBT Victimization Experiences measure. This questionnaire consists of 10 items. The LGBT victimization scale is rated on a 0 Never to 3 3+ times scale with a total score range 0-30. The total score reflects the amount of victimization one has experienced due to being known or thought to be LGBTQ. Higher scores indicate more negative experiences.
Change in Religious AffiliationBaseline, Post Intervention (day 5), and 3 Months.Tolerance of one's sexual orientation through the lense of one's practiced religion is measured using a single question. Respondents use a 1-7 scale to rate the question How tolerant is your religion toward your sexual orientation?- where 7 indicates total rejection and hostility.
Change in Religious StrainBaseline, Post Intervention (day 5), and 3 Months.Religious Strain Scale total score obtained by reverse scoring items 1-7 and then summing across the 20 items (range 0-60), higher scores indicate greater religious strain.
Change in Internalized HomophobiaBaseline, Post Intervention (day 5), and 3 Months.Internalized homophobia in participants will be assessed using the Internalized Homophobia Scale (IHS). The IHS score is obtained by averaging the scores across the 9 items (rather than summing). Range is 1-4, with higher scores indicating higher internalized stigma related to one's sexual orientation.
RuminationBaseline, Post Intervention (day 5), and 3 Months.Rumination will be assessed using the Ruminative Response Scale - Brooding Subscale (RRS). This scale is modified from the original measure where only items 5, 10, 13, 15 and 16 are used. Each item is scored by respondents on a scale of 1 to 4. To get the overall score, the 5 items are summed; total scores range from 5-20, with higher scores indicating greater brooding and rumination (related to depression) in an individual.
Perceived SupportBaseline, Post Intervention (day 5), and 3 Months.Perceived social support is measured using the Multidimensional Scale of Perceived Social Support (MSPSS). The MSPSS is a 12 item instrument that uses a scale 1-7 to rate each item. The scoring is done by taking the average of the items- therefore a score of 7 indicates the highest level of perceived social support.
HopelessnessBaseline, Post Intervention, 3 MonthsHopelessness will be measured using the Beck Hopelessness Scale (BHS). The BHS is a 20-item dichotomous scale (No = 0, Yes = 1). Items 1, 3, 5, 6, 8, 10, 13, 15 and 19 are reverse-scored. The total score is out of 20, where 20 would be the highest score and considered a negative indicator of hopelessness.
Lesbian, Gay, Bisexual (LGB) IdentityBaseline, Post Intervention (day 5), and 3 Months.LGB identity will be measured using the 'LGB Identity Centrality' instrument.The measure consists of 4 items that are rated on a scale of 1-7. The summed scores have a range of 4-28 and the higher score would indicate a stong agreement (positive) with the centrality of one's LGB identity.
Change in Cortisol1 and 4 months post baseline.Participants will provide 50-100 hair strands (at least 2 cm in length) to be used to determine levels of stress based on the cortisol levels found in the analyses of the hair provided.
Change in StressBaseline, Post Intervention (day 5), and 3 Months.Stress will be assessed using the Perceived Stress Scale (PSS). Participants were asked to respond to the 14-item version. Participants respond to each item on a 0-4 scale and scores are obtained by reversing responses to the 7 positively stated items (items 4,5,6,7,9,10, & 13), and then summing across all scale items. Range = 0-56. Higher scores indicating higher perceived stress.
Change in Impulsiveness Total ScoreBaseline, Post Intervention (day 5), and 3 Months.Impulsiveness will be assessed using the Barratt Impulsiveness Scale (BIS). The BIS is a 30 item questionnaire that uses a 1-4 rating scale per item. The 30-item self-report questionnaire, can yield a total score where the range is 30-120. The highest score indicates the greatest the level of impulsiveness.

Countries

United States

Participant flow

Recruitment details

Participants were specifically recruited through tailored advertising on geo-targeted websites; bulletin boards and listservs of local colleges; in-person announcement and flyers at local businesses, community events, and the gay-straight alliances of area schools. Participants completed a brief online survey to confirm eligibility.

Pre-assignment details

Participants completed a brief online survey to confirm eligibility, defined as: age 18 -29; identifying as sexual minority; currently living in one of the eligible counties; and having daily personal Internet access. Participants emailed a photo of an identification card(e.g. a driver's license), as proof of age. 108 people were randomized.

Participants by arm

ArmCount
Control
Participants randomly assigned to the control condition will be asked to write about what they have done since waking up that morning for 20 minutes across 3 consecutive days. Control: Participants randomly assigned to the control condition will be asked to write about what they have done since waking up that morning for 20 minutes across 3 consecutive days. This control matches the time and activity of the EW and SA arms and has been implemented across dozens of EW and SA studies.
36
Expressive Writing (EW)
Expressive Writing (EW) prompts individuals to write about personally stressful events, potentially enabling cognitive processing of unresolved, psychological and physiological stressors. Expressive Writing (EW) Intervention: The EW intervention will utilize the procedures piloted earlier with gay and bisexual male college students in urban and rural regions of the US. In this condition, participants will be instructed to write for 20 minutes across three consecutive days in a free-form manner about the most stressful or traumatic LGB-related event that they have encountered.
36
Self-Affirmation (SA)
Self-Affirmation (SA) interventions prompt individuals to write advice to a (hypothetical) similarly stigmatized person regarding how best to cope with stigma-related stress. By affirming one's own stigmatized identity through the process of helping another similarly stigmatized person. Self-Affirmation (SA) Intervention: The SA intervention will ask participants to read a brief description, over the course of 3 consecutive days, of a (hypothetical) LGB youth who is facing minority stress. Each day's description will contain a different LGB youth facing a different stigma-related stressor derived from Phase 1 and 2 interviews. Participants will then be asked to write a letter for 20 minutes to advise the LGB youth how best to cope with minority stress drawing on their personal experiences.
36
Total108

Withdrawals & dropouts

PeriodReasonFG000FG001FG002
Overall StudyLost to Follow-up7410
Overall StudyWithdrawal by Subject200

Baseline characteristics

CharacteristicExpressive Writing (EW)TotalControlSelf-Affirmation (SA)
Age, Continuous23.47 years
STANDARD_DEVIATION 2.88
23.68 years
STANDARD_DEVIATION 3.11
24.14 years
STANDARD_DEVIATION 3.24
23.42 years
STANDARD_DEVIATION 3.25
Education Level
College Degree
17 Participants50 Participants18 Participants15 Participants
Education Level
Less than College
19 Participants58 Participants18 Participants21 Participants
Employment Status
Full-time
13 Participants41 Participants14 Participants14 Participants
Employment Status
Part-time
13 Participants46 Participants21 Participants12 Participants
Employment Status
Student
5 Participants11 Participants0 Participants6 Participants
Employment Status
Unemployed
5 Participants10 Participants1 Participants4 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
0 Participants2 Participants1 Participants1 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
36 Participants106 Participants35 Participants35 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants0 Participants0 Participants0 Participants
Family Class Background
Lower Middle Class
4 Participants17 Participants8 Participants5 Participants
Family Class Background
Middle Class
11 Participants32 Participants10 Participants11 Participants
Family Class Background
Poor
7 Participants16 Participants3 Participants6 Participants
Family Class Background
Upper Middle Class
3 Participants7 Participants3 Participants1 Participants
Family Class Background
Working Class
11 Participants36 Participants12 Participants13 Participants
Personal Income
Less than $10,000
17 Participants41 Participants11 Participants13 Participants
Personal Income
More than $10,000
19 Participants67 Participants25 Participants23 Participants
Race/Ethnicity, Customized
American Indian /Alaskan Native
2 Participants2 Participants0 Participants0 Participants
Race/Ethnicity, Customized
Asian
0 Participants1 Participants1 Participants0 Participants
Race/Ethnicity, Customized
Black/African American
4 Participants10 Participants2 Participants4 Participants
Race/Ethnicity, Customized
Native Hawaiian/Pacific Islander
0 Participants1 Participants1 Participants0 Participants
Race/Ethnicity, Customized
Other
0 Participants1 Participants1 Participants0 Participants
Race/Ethnicity, Customized
White
33 Participants100 Participants33 Participants34 Participants
Region of Enrollment
United States
36 participants108 participants36 participants36 participants
Relationship Status
In a Relationship
26 Participants73 Participants25 Participants22 Participants
Relationship Status
Single
10 Participants35 Participants11 Participants14 Participants
Sex: Female, Male
Female
26 Participants77 Participants25 Participants26 Participants
Sex: Female, Male
Male
10 Participants31 Participants11 Participants10 Participants
Sex/Gender, Customized
Gender Non-Conforming/Binary
3 Participants10 Participants3 Participants4 Participants
Sex/Gender, Customized
Gender Queer
2 Participants10 Participants4 Participants4 Participants
Sex/Gender, Customized
Man
12 Participants31 Participants10 Participants9 Participants
Sex/Gender, Customized
Other
2 Participants5 Participants2 Participants1 Participants
Sex/Gender, Customized
Transgender Man
3 Participants7 Participants1 Participants3 Participants
Sex/Gender, Customized
Transgender Woman
0 Participants1 Participants1 Participants0 Participants
Sex/Gender, Customized
Two-spirit
0 Participants1 Participants0 Participants1 Participants
Sex/Gender, Customized
Woman
21 Participants60 Participants20 Participants19 Participants
Sexual Orientation
Asexual
1 Participants2 Participants0 Participants1 Participants
Sexual Orientation
Bisexual
9 Participants30 Participants13 Participants8 Participants
Sexual Orientation
Gay
9 Participants26 Participants8 Participants9 Participants
Sexual Orientation
Lesbian
9 Participants30 Participants12 Participants9 Participants
Sexual Orientation
Other
2 Participants4 Participants0 Participants2 Participants
Sexual Orientation
Pansexual
6 Participants15 Participants3 Participants6 Participants
Sexual Orientation
Questioning
0 Participants1 Participants0 Participants1 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
EG002
affected / at risk
deaths
Total, all-cause mortality
0 / 360 / 360 / 36
other
Total, other adverse events
0 / 360 / 360 / 36
serious
Total, serious adverse events
0 / 360 / 360 / 36

Outcome results

Primary

Attempted Suicide

Suicide attempts will be assessed using a single item that asks: Within the last past 3 months/past week, have you actually attempted suicide? \[yes/no\]. Reported are the number of participants who reported that they had attempted suicide. Original title: Change in Suicidality: Suicide Attempts.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed intention to treat.

ArmMeasureGroupValue (COUNT_OF_PARTICIPANTS)
ControlAttempted Suicide3 Months0 Participants
ControlAttempted SuicidePost-Intervention0 Participants
ControlAttempted SuicideBaseline1 Participants
Expressive Writing (EW)Attempted SuicidePost-Intervention0 Participants
Expressive Writing (EW)Attempted Suicide3 Months0 Participants
Expressive Writing (EW)Attempted SuicideBaseline0 Participants
Self-Affirmation (SA)Attempted Suicide3 Months0 Participants
Self-Affirmation (SA)Attempted SuicideBaseline1 Participants
Self-Affirmation (SA)Attempted SuicidePost-Intervention0 Participants
Primary

Change in Alcohol Use.

Alcohol use in participants will be assessed using the Alcohol Use Disorders Identification (AUDIT) instrument. The AUDIT consists of 10 items. Each of the questions has a set of responses to choose from, and each response has a score ranging from 0 to 4. All response scores should be added and recorded as Total. Total scores of 8 or more are recommended as indicators of hazardous and harmful alcohol use, as well as possible alcohol dependence. (A cut-off score of 10 will provide greater specificity but at the expense of sensitivity.) The score range is 0-40. Higher scores indicate greater hazardous drinking.

Time frame: Baseline, Post Intervention, 3 Months

Population: Data were analyzed intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Alcohol Use.3 Months5.26 units on a scaleStandard Deviation 4.62
ControlChange in Alcohol Use.Baseline5.08 units on a scaleStandard Deviation 3.77
ControlChange in Alcohol Use.Post-Intervention4.67 units on a scaleStandard Deviation 4
Expressive Writing (EW)Change in Alcohol Use.3 Months2.91 units on a scaleStandard Deviation 3.76
Expressive Writing (EW)Change in Alcohol Use.Baseline4.25 units on a scaleStandard Deviation 4.29
Expressive Writing (EW)Change in Alcohol Use.Post-Intervention3.70 units on a scaleStandard Deviation 4.33
Self-Affirmation (SA)Change in Alcohol Use.3 Months5.58 units on a scaleStandard Deviation 5.98
Self-Affirmation (SA)Change in Alcohol Use.Baseline5.97 units on a scaleStandard Deviation 6
Self-Affirmation (SA)Change in Alcohol Use.Post-Intervention3.73 units on a scaleStandard Deviation 4.35
Comparison: The primary comparison was between EW and control to test the interaction between treatment and time.p-value: 0.195% CI: [-2.8, 0.24]Mixed Models Analysis
Primary

Change in Anxiety.

Anxiety will be measured using the Beck Anxiety Inventory (BAI). The BAI total score is reported, which is the sum of all 21 items; with no subscales. The range of scores is 0-63, with higher scores indicating higher anxiety.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Anxiety.Post-Intervention14.73 units on a scaleStandard Deviation 13.43
ControlChange in Anxiety.Baseline21.72 units on a scaleStandard Deviation 14.14
ControlChange in Anxiety.3 Months18.26 units on a scaleStandard Deviation 13.19
Expressive Writing (EW)Change in Anxiety.Post-Intervention13.54 units on a scaleStandard Deviation 10.91
Expressive Writing (EW)Change in Anxiety.3 Months13.03 units on a scaleStandard Deviation 10.55
Expressive Writing (EW)Change in Anxiety.Baseline20.28 units on a scaleStandard Deviation 12.29
Self-Affirmation (SA)Change in Anxiety.Baseline26.94 units on a scaleStandard Deviation 13.91
Self-Affirmation (SA)Change in Anxiety.3 Months19.73 units on a scaleStandard Deviation 10.78
Self-Affirmation (SA)Change in Anxiety.Post-Intervention19.47 units on a scaleStandard Deviation 13.16
Comparison: The primary comparison was between EW and control to test the interaction between treatment and time.p-value: 0.0795% CI: [-8.55, 0.47]Mixed Models Analysis
Primary

Change in Depression.

Depression will be measured using the Center for Epidemiological Studies -- Depression Scale (CESD). An overall depression score is computed as the sum of 20 items, with items 3, 11, 14, and 16 reversed. In cases with internally missing data (items not answered), the sums are computed after imputation of the missing values: # items on scale / # actually answered, multiplied by the sum obtained from the answered items. A range of 0-60, with higher scores indicating more depressive symptomatology during the past week.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Depression.3 Months23.44 units on a scaleStandard Deviation 13.09
ControlChange in Depression.Baseline24.75 units on a scaleStandard Deviation 11.83
ControlChange in Depression.Post-Intervention21.03 units on a scaleStandard Deviation 11.79
Expressive Writing (EW)Change in Depression.Baseline25.17 units on a scaleStandard Deviation 12.07
Expressive Writing (EW)Change in Depression.Post-Intervention17.42 units on a scaleStandard Deviation 11.46
Expressive Writing (EW)Change in Depression.3 Months18.45 units on a scaleStandard Deviation 10.97
Self-Affirmation (SA)Change in Depression.Post-Intervention21.73 units on a scaleStandard Deviation 13.45
Self-Affirmation (SA)Change in Depression.Baseline29.06 units on a scaleStandard Deviation 13.41
Self-Affirmation (SA)Change in Depression.3 Months22.92 units on a scaleStandard Deviation 14.61
Comparison: The primary comparison was between EW and control to test the interaction between treatment and time.p-value: <0.0195% CI: [-11.03, -1.64]Mixed Models Analysis
Primary

Change in Drug Use.

The Short Inventory of Problems-Modified for Drug Use (SIP-DU) is a 15-item scale that asks respondents to rate each item on a dichotomous scale (No = 0, Yes = 1). Total score reported, which is the sum of all items; no subscales: Range 0-15, higher scores indicate greater problems with drug use.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Drug Use.Post-Intervention0.36 units on a scaleStandard Deviation 1.03
ControlChange in Drug Use.Baseline0.39 units on a scaleStandard Deviation 0.99
ControlChange in Drug Use.3 Months0.33 units on a scaleStandard Deviation 0.83
Expressive Writing (EW)Change in Drug Use.Post-Intervention0.67 units on a scaleStandard Deviation 2.53
Expressive Writing (EW)Change in Drug Use.Baseline0.31 units on a scaleStandard Deviation 0.98
Expressive Writing (EW)Change in Drug Use.3 Months0.84 units on a scaleStandard Deviation 2.89
Self-Affirmation (SA)Change in Drug Use.Baseline1.47 units on a scaleStandard Deviation 2.99
Self-Affirmation (SA)Change in Drug Use.3 Months1.58 units on a scaleStandard Deviation 3.56
Self-Affirmation (SA)Change in Drug Use.Post-Intervention0.57 units on a scaleStandard Deviation 1.7
Comparison: The primary comparison was between EW and control to test the interaction between treatment and time.p-value: 0.7695% CI: [-1.19, 1.57]Mixed Models Analysis
Primary

Change in Psychological Distress.

Psychological Distress will be measured using the Brief Symptom Inventory (BSI). The BSI consists of 18 items scored 0-4. Items are averaged to yield a final score of 0-4. The higher the score, the greater the psychological distress.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Psychological Distress.Baseline2.31 units on a scaleStandard Deviation 0.85
ControlChange in Psychological Distress.Post-Intervention1.84 units on a scaleStandard Deviation 0.77
ControlChange in Psychological Distress.3 Months2.14 units on a scaleStandard Deviation 0.92
Expressive Writing (EW)Change in Psychological Distress.3 Months1.77 units on a scaleStandard Deviation 0.65
Expressive Writing (EW)Change in Psychological Distress.Baseline2.22 units on a scaleStandard Deviation 0.73
Expressive Writing (EW)Change in Psychological Distress.Post-Intervention1.82 units on a scaleStandard Deviation 0.67
Self-Affirmation (SA)Change in Psychological Distress.3 Months2.35 units on a scaleStandard Deviation 0.8
Self-Affirmation (SA)Change in Psychological Distress.Baseline2.63 units on a scaleStandard Deviation 0.86
Self-Affirmation (SA)Change in Psychological Distress.Post-Intervention2.08 units on a scaleStandard Deviation 0.86
Comparison: The primary comparison was between EW and control to test the interaction between treatment and time.p-value: 0.0395% CI: [-0.62, -0.03]Mixed Models Analysis
Primary

Change in Suicidality - Suicidal Ideation.

Suicidal ideation will be measured using the Suicidal Ideation Attributes Scale (SIDAS) . Total SIDAS scores are calculated as the sum of the five items, with controllability reverse scored (10=0, 9=1, …, 0=10). Total scores range from 0 to 50.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Suicidality - Suicidal Ideation.Baseline6.05 units on a scaleStandard Deviation 9.81
ControlChange in Suicidality - Suicidal Ideation.3 Months4.63 units on a scaleStandard Deviation 8.19
ControlChange in Suicidality - Suicidal Ideation.Post-Intervention2.36 units on a scaleStandard Deviation 4.08
Expressive Writing (EW)Change in Suicidality - Suicidal Ideation.Baseline4.19 units on a scaleStandard Deviation 6.92
Expressive Writing (EW)Change in Suicidality - Suicidal Ideation.Post-Intervention1.21 units on a scaleStandard Deviation 3.57
Expressive Writing (EW)Change in Suicidality - Suicidal Ideation.3 Months3.87 units on a scaleStandard Deviation 7.4
Self-Affirmation (SA)Change in Suicidality - Suicidal Ideation.Baseline9.42 units on a scaleStandard Deviation 11.21
Self-Affirmation (SA)Change in Suicidality - Suicidal Ideation.3 Months5.31 units on a scaleStandard Deviation 7.54
Self-Affirmation (SA)Change in Suicidality - Suicidal Ideation.Post-Intervention2.70 units on a scaleStandard Deviation 6.24
Comparison: The primary comparison was between EW and control to test the interaction between treatment and time.p-value: 0.7395% CI: [-6.48, 8.77]Mixed Models Analysis
Primary

Suicidal Intent

Suicidal intent will be assessed using a single item that asks: Within the last 3 months/past week, have you seriously considered attempting suicide? \[yes/no\] Number of participants who reported suicidal intent is reported. Originally titled Change in Suicidality - Suicidal Thoughts.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed intention to treat.

ArmMeasureGroupValue (COUNT_OF_PARTICIPANTS)
ControlSuicidal IntentPost-Intervention0 Participants
ControlSuicidal IntentBaseline4 Participants
ControlSuicidal Intent3 Months3 Participants
Expressive Writing (EW)Suicidal IntentPost-Intervention0 Participants
Expressive Writing (EW)Suicidal IntentBaseline4 Participants
Expressive Writing (EW)Suicidal Intent3 Months1 Participants
Self-Affirmation (SA)Suicidal IntentBaseline9 Participants
Self-Affirmation (SA)Suicidal Intent3 Months2 Participants
Self-Affirmation (SA)Suicidal IntentPost-Intervention1 Participants
Secondary

Change in Cortisol

Participants will provide 50-100 hair strands (at least 2 cm in length) to be used to determine levels of stress based on the cortisol levels found in the analyses of the hair provided.

Time frame: 1 and 4 months post baseline.

Population: Data were analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Cortisol4 Months10.37 pg/mgStandard Deviation 10.18
ControlChange in Cortisol1 Month10.12 pg/mgStandard Deviation 12.2
Expressive Writing (EW)Change in Cortisol1 Month8.28 pg/mgStandard Deviation 10.96
Expressive Writing (EW)Change in Cortisol4 Months6.18 pg/mgStandard Deviation 5.49
Self-Affirmation (SA)Change in Cortisol1 Month10.91 pg/mgStandard Deviation 15.85
Self-Affirmation (SA)Change in Cortisol4 Months12.21 pg/mgStandard Deviation 28.72
Secondary

Change in Discrimination - 9 Items (Part 1)

Everyday discrimination experienced by participants will be measured using the Everyday Discrimination - Sexual Orientation (EDSO) Part 1. Part 1 is a 9 item inventory where respondents rate statements on a scale of 1-6. The scale has a summed total score ranging from 9-54, higher scores indicate higher discrimination. The higher the score, the greater the feeling that one is discriminated against for one's sexual orientation.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Discrimination - 9 Items (Part 1)Post Intervention18.61 units on a scaleStandard Deviation 9.47
ControlChange in Discrimination - 9 Items (Part 1)Baseline19.75 units on a scaleStandard Deviation 10.63
ControlChange in Discrimination - 9 Items (Part 1)3 Months17.81 units on a scaleStandard Deviation 9.22
Expressive Writing (EW)Change in Discrimination - 9 Items (Part 1)Post Intervention17.88 units on a scaleStandard Deviation 7.27
Expressive Writing (EW)Change in Discrimination - 9 Items (Part 1)Baseline19.22 units on a scaleStandard Deviation 7.26
Expressive Writing (EW)Change in Discrimination - 9 Items (Part 1)3 Months16.87 units on a scaleStandard Deviation 7.49
Self-Affirmation (SA)Change in Discrimination - 9 Items (Part 1)Baseline21.14 units on a scaleStandard Deviation 8.72
Self-Affirmation (SA)Change in Discrimination - 9 Items (Part 1)3 Months17.81 units on a scaleStandard Deviation 8.64
Self-Affirmation (SA)Change in Discrimination - 9 Items (Part 1)Post Intervention20.47 units on a scaleStandard Deviation 9.42
Secondary

Change in Discrimination - Item 1 (Part 2)

Everyday discrimination experienced by participants will be measured using the Everyday Discrimination - Sexual Orientation (EDSO) Part 2. Part 2 is a 2 item inventory where respondents rate statements on a scale of 0-3. The lower the score, the less the feeling that one is discriminated against overall for one's sexual orientation. Item 1: Overall, how much has discrimination based on your sexual orientation interfered with you having a full and productive life?

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Discrimination - Item 1 (Part 2)3 Months0.74 units on a scaleStandard Deviation 0.81
ControlChange in Discrimination - Item 1 (Part 2)Post Intervention0.67 units on a scaleStandard Deviation 0.66
ControlChange in Discrimination - Item 1 (Part 2)Baseline0.78 units on a scaleStandard Deviation 0.76
Expressive Writing (EW)Change in Discrimination - Item 1 (Part 2)3 Months0.87 units on a scaleStandard Deviation 0.72
Expressive Writing (EW)Change in Discrimination - Item 1 (Part 2)Baseline0.89 units on a scaleStandard Deviation 0.82
Expressive Writing (EW)Change in Discrimination - Item 1 (Part 2)Post Intervention1.00 units on a scaleStandard Deviation 0.79
Self-Affirmation (SA)Change in Discrimination - Item 1 (Part 2)Post Intervention0.97 units on a scaleStandard Deviation 0.89
Self-Affirmation (SA)Change in Discrimination - Item 1 (Part 2)Baseline1.19 units on a scaleStandard Deviation 0.98
Self-Affirmation (SA)Change in Discrimination - Item 1 (Part 2)3 Months0.73 units on a scaleStandard Deviation 0.87
Secondary

Change in Discrimination - Item 2 (Part 2)

Everyday discrimination experienced by participants will be measured using the Everyday Discrimination - Sexual Orientation (EDSO) Part 2. Part 2 is a 2 item inventory where respondents rate statements on a scale of 0-3. The lower the score, the less the feeling that one is discriminated against overall for one's sexual orientation. Item 2: Overall, how much harder has your life been because of discrimination based on your sexual orientation?

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Discrimination - Item 2 (Part 2)Baseline1.03 units on a scaleStandard Deviation 0.81
ControlChange in Discrimination - Item 2 (Part 2)Post Intervention1.00 units on a scaleStandard Deviation 0.79
ControlChange in Discrimination - Item 2 (Part 2)3 Months0.85 units on a scaleStandard Deviation 0.72
Expressive Writing (EW)Change in Discrimination - Item 2 (Part 2)Post Intervention1.24 units on a scaleStandard Deviation 0.87
Expressive Writing (EW)Change in Discrimination - Item 2 (Part 2)3 Months1.06 units on a scaleStandard Deviation 0.73
Expressive Writing (EW)Change in Discrimination - Item 2 (Part 2)Baseline1.42 units on a scaleStandard Deviation 0.87
Self-Affirmation (SA)Change in Discrimination - Item 2 (Part 2)Post Intervention1.30 units on a scaleStandard Deviation 1.02
Self-Affirmation (SA)Change in Discrimination - Item 2 (Part 2)3 Months1.15 units on a scaleStandard Deviation 0.97
Self-Affirmation (SA)Change in Discrimination - Item 2 (Part 2)Baseline1.53 units on a scaleStandard Deviation 0.91
Secondary

Change in Impulsiveness- Attentional

Impulsiveness will be assessed using the Barratt Impulsiveness Scale (BIS). The BIS is a 30 item questionnaire that uses a 1-4 rating scale per item. The 30-item self-report questionnaire, can yield a total score, as well as three factors: attentional (6, 5, 9, 11, 20, 24, 26, 28; motor (2, 3, 4, 16, 17, 19, 21, 22, 23, 25, 30); non-planning (1, 7, 8, 10, 12, 13, 14, 15, 18, 27, 29). The attentional scale has a range of 8-32, the greater the value, the greater the level of attentional impulsiveness.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Impulsiveness- AttentionalBaseline16.36 units on a scaleStandard Deviation 4.98
ControlChange in Impulsiveness- Attentional3 Months15.43 units on a scaleStandard Deviation 4.33
ControlChange in Impulsiveness- AttentionalPost-Intervention15.79 units on a scaleStandard Deviation 4.69
Expressive Writing (EW)Change in Impulsiveness- Attentional3 Months15.75 units on a scaleStandard Deviation 4.19
Expressive Writing (EW)Change in Impulsiveness- AttentionalBaseline16.44 units on a scaleStandard Deviation 4.59
Expressive Writing (EW)Change in Impulsiveness- AttentionalPost-Intervention15.64 units on a scaleStandard Deviation 4.62
Self-Affirmation (SA)Change in Impulsiveness- AttentionalPost-Intervention16.70 units on a scaleStandard Deviation 4.19
Self-Affirmation (SA)Change in Impulsiveness- Attentional3 Months16.69 units on a scaleStandard Deviation 5.53
Self-Affirmation (SA)Change in Impulsiveness- AttentionalBaseline16.33 units on a scaleStandard Deviation 4.11
Secondary

Change in Impulsiveness- Motor

Impulsiveness will be assessed using the Barratt Impulsiveness Scale (BIS-11). The BIS-11 is a 30 item questionnaire that uses a 1-4 rating scale per item. The 30-item self-report questionnaire, can yield a total score, as well as three factors: attentional (6, 5, 9, 11, 20, 24, 26, 28; motor (2, 3, 4, 16, 17, 19, 21, 22, 23, 25, 30); non-planning (1, 7, 8, 10, 12, 13, 14, 15, 18, 27, 29). The motor scale has a range of 11-44, the greater the value, the greater the level of motor impulsiveness.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Impulsiveness- Motor3 Months21.96 units on a scaleStandard Deviation 5.17
ControlChange in Impulsiveness- MotorBaseline20.78 units on a scaleStandard Deviation 4.33
ControlChange in Impulsiveness- MotorPost-Intervention15.71 units on a scaleStandard Deviation 5.01
Expressive Writing (EW)Change in Impulsiveness- Motor3 Months21.23 units on a scaleStandard Deviation 4.18
Expressive Writing (EW)Change in Impulsiveness- MotorBaseline20.78 units on a scaleStandard Deviation 4
Expressive Writing (EW)Change in Impulsiveness- MotorPost-Intervention20.52 units on a scaleStandard Deviation 3.94
Self-Affirmation (SA)Change in Impulsiveness- Motor3 Months20.27 units on a scaleStandard Deviation 3.11
Self-Affirmation (SA)Change in Impulsiveness- MotorPost-Intervention21.23 units on a scaleStandard Deviation 4.16
Self-Affirmation (SA)Change in Impulsiveness- MotorBaseline21.39 units on a scaleStandard Deviation 4.14
Secondary

Change in Impulsiveness- Non-Planning

Impulsiveness will be assessed using the Barratt Impulsiveness Scale (BIS-11). The BIS-11 is a 30 item questionnaire that uses a 1-4 rating scale per item. The 30-item self-report questionnaire, can yield a total score, as well as three factors: attentional (6, 5, 9, 11, 20, 24, 26, 28; motor (2, 3, 4, 16, 17, 19, 21, 22, 23, 25, 30); non-planning (1, 7, 8, 10, 12, 13, 14, 15, 18, 27, 29). The non-planning scale has a range of 11-44, the greater the value, the greater the level of non-planning impulsiveness.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Impulsiveness- Non-PlanningBaseline17.00 units on a scaleStandard Deviation 5.2
ControlChange in Impulsiveness- Non-PlanningPost-Intervention15.71 units on a scaleStandard Deviation 5.01
ControlChange in Impulsiveness- Non-Planning3 Months16.00 units on a scaleStandard Deviation 4.74
Expressive Writing (EW)Change in Impulsiveness- Non-Planning3 Months17.16 units on a scaleStandard Deviation 6.06
Expressive Writing (EW)Change in Impulsiveness- Non-PlanningBaseline16.80 units on a scaleStandard Deviation 5.59
Expressive Writing (EW)Change in Impulsiveness- Non-PlanningPost-Intervention16.61 units on a scaleStandard Deviation 6.58
Self-Affirmation (SA)Change in Impulsiveness- Non-Planning3 Months16.62 units on a scaleStandard Deviation 4.98
Self-Affirmation (SA)Change in Impulsiveness- Non-PlanningPost-Intervention16.13 units on a scaleStandard Deviation 5.31
Self-Affirmation (SA)Change in Impulsiveness- Non-PlanningBaseline16.58 units on a scaleStandard Deviation 5.18
Secondary

Change in Impulsiveness Total Score

Impulsiveness will be assessed using the Barratt Impulsiveness Scale (BIS). The BIS is a 30 item questionnaire that uses a 1-4 rating scale per item. The 30-item self-report questionnaire, can yield a total score where the range is 30-120. The highest score indicates the greatest the level of impulsiveness.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Impulsiveness Total ScorePost-Intervention52.35 units on a scaleStandard Deviation 10.5
ControlChange in Impulsiveness Total ScoreBaseline53.75 units on a scaleStandard Deviation 11.92
ControlChange in Impulsiveness Total Score3 Months53.39 units on a scaleStandard Deviation 11.38
Expressive Writing (EW)Change in Impulsiveness Total ScorePost-Intervention52.76 units on a scaleStandard Deviation 12.34
Expressive Writing (EW)Change in Impulsiveness Total Score3 Months54.14 units on a scaleStandard Deviation 11.43
Expressive Writing (EW)Change in Impulsiveness Total ScoreBaseline51.03 units on a scaleStandard Deviation 11.31
Self-Affirmation (SA)Change in Impulsiveness Total ScoreBaseline54.31 units on a scaleStandard Deviation 4.11
Self-Affirmation (SA)Change in Impulsiveness Total Score3 Months53.58 units on a scaleStandard Deviation 9.37
Self-Affirmation (SA)Change in Impulsiveness Total ScorePost-Intervention54.06 units on a scaleStandard Deviation 11.36
Secondary

Change in Internalized Homophobia

Internalized homophobia in participants will be assessed using the Internalized Homophobia Scale (IHS). The IHS score is obtained by averaging the scores across the 9 items (rather than summing). Range is 1-4, with higher scores indicating higher internalized stigma related to one's sexual orientation.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Internalized HomophobiaBaseline1.42 units on a scaleStandard Deviation 0.57
ControlChange in Internalized Homophobia3 Months1.29 units on a scaleStandard Deviation 0.63
ControlChange in Internalized HomophobiaPost-Intervention1.27 units on a scaleStandard Deviation 0.64
Expressive Writing (EW)Change in Internalized Homophobia3 Months1.39 units on a scaleStandard Deviation 0.57
Expressive Writing (EW)Change in Internalized HomophobiaBaseline1.38 units on a scaleStandard Deviation 0.5
Expressive Writing (EW)Change in Internalized HomophobiaPost-Intervention1.27 units on a scaleStandard Deviation 0.53
Self-Affirmation (SA)Change in Internalized HomophobiaBaseline1.58 units on a scaleStandard Deviation 0.65
Self-Affirmation (SA)Change in Internalized Homophobia3 Months1.52 units on a scaleStandard Deviation 0.58
Self-Affirmation (SA)Change in Internalized HomophobiaPost-Intervention1.56 units on a scaleStandard Deviation 0.58
Secondary

Change in Minority Stress (Rejection)

To assess rejection as a form of minority stress, the Gay-Related Rejection Sensitivity Scale (GRRS) will be used.The Gay-related rejection sensitivity scale was adapted for this study to be gender-inclusive and has 12 items. Scale range 1-36, where higher scores indicate greater rejection sensitivity based on one's sexual orientation (worse outcome).

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Minority Stress (Rejection)3 Months12.17 units on a scaleStandard Deviation 8.16
ControlChange in Minority Stress (Rejection)Baseline14.47 units on a scaleStandard Deviation 7.35
ControlChange in Minority Stress (Rejection)Post-Intervention12.92 units on a scaleStandard Deviation 8.23
Expressive Writing (EW)Change in Minority Stress (Rejection)Post-Intervention10.95 units on a scaleStandard Deviation 6.51
Expressive Writing (EW)Change in Minority Stress (Rejection)3 Months9.31 units on a scaleStandard Deviation 7.6
Expressive Writing (EW)Change in Minority Stress (Rejection)Baseline12.33 units on a scaleStandard Deviation 6.11
Self-Affirmation (SA)Change in Minority Stress (Rejection)3 Months12.33 units on a scaleStandard Deviation 5.65
Self-Affirmation (SA)Change in Minority Stress (Rejection)Baseline14.94 units on a scaleStandard Deviation 7.43
Self-Affirmation (SA)Change in Minority Stress (Rejection)Post-Intervention12.99 units on a scaleStandard Deviation 6.41
Secondary

Change in Outness

Participants openness about one's sexual orientation will be assessed using the Outness Inventory (OI). A respondent is asked to rate how open they are with various people in society (from family to strangers) on an 11 item questionnaire. The scale for responding is 0-7- where 7 indicates that a person is completely open with their sexual orientation status. The scale score is obtained by averaging the 11 items for a score range of 0-7, where higher scores indicate more openness about respondents' sexual orientation in different domains of their lives/different people. 0 indicates that an item does not apply/ there is no such group of people/person in the respondents' life. A score of 7 would indicate that one is completely open or out with respect to sexual orientation.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in OutnessPost-Intervention4.55 units on a scaleStandard Deviation 1.66
ControlChange in OutnessBaseline4.46 units on a scaleStandard Deviation 1.56
ControlChange in Outness3 Months4.95 units on a scaleStandard Deviation 1.49
Expressive Writing (EW)Change in Outness3 Months5.16 units on a scaleStandard Deviation 1.49
Expressive Writing (EW)Change in OutnessPost-Intervention5.13 units on a scaleStandard Deviation 1.39
Expressive Writing (EW)Change in OutnessBaseline5.32 units on a scaleStandard Deviation 1.43
Self-Affirmation (SA)Change in OutnessBaseline5.05 units on a scaleStandard Deviation 1.4
Self-Affirmation (SA)Change in OutnessPost-Intervention4.94 units on a scaleStandard Deviation 1.21
Self-Affirmation (SA)Change in Outness3 Months5.01 units on a scaleStandard Deviation 1.33
Secondary

Change in Parental Attitudes

The participant's perception of their parent's attitudes towards their sexual orientation are assessed using the Parental Attitudes Toward Child's Sexual Orientation. This tool has 4 items- 2 that deal with mother/parent 1/closest female guardian, 2 that deal with father/parent 2/closest male guardian. The second item for each parent asks about their attitude towards the respondent's sexual orientation on a scale from 1 (completely tolerant and accepting) to 7 (completely hostile and rejecting). Scores for maternal and paternal attitude should be averaged for each participant. The score has a range from 1-7, where higher scores indicate greater rejection from parents (worse outcome).

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzes as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Parental AttitudesBaseline2.85 units on a scaleStandard Deviation 1.5
ControlChange in Parental Attitudes3 Months2.75 units on a scaleStandard Deviation 1.46
ControlChange in Parental AttitudesPost-Intervention2.71 units on a scaleStandard Deviation 1.21
Expressive Writing (EW)Change in Parental AttitudesPost-Intervention2.60 units on a scaleStandard Deviation 1.47
Expressive Writing (EW)Change in Parental AttitudesBaseline2.59 units on a scaleStandard Deviation 1.52
Expressive Writing (EW)Change in Parental Attitudes3 Months2.63 units on a scaleStandard Deviation 1.36
Self-Affirmation (SA)Change in Parental Attitudes3 Months2.68 units on a scaleStandard Deviation 1.48
Self-Affirmation (SA)Change in Parental AttitudesBaseline2.61 units on a scaleStandard Deviation 1.46
Self-Affirmation (SA)Change in Parental AttitudesPost-Intervention2.36 units on a scaleStandard Deviation 1.28
Secondary

Change in Religious Affiliation

Tolerance of one's sexual orientation through the lense of one's practiced religion is measured using a single question. Respondents use a 1-7 scale to rate the question How tolerant is your religion toward your sexual orientation?- where 7 indicates total rejection and hostility.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Religious Affiliation3 Months2.20 units on a scaleStandard Deviation 1.47
ControlChange in Religious AffiliationPost Intervention2.78 units on a scaleStandard Deviation 1.57
ControlChange in Religious AffiliationBaseline2.70 units on a scaleStandard Deviation 1.86
Expressive Writing (EW)Change in Religious Affiliation3 Months2.56 units on a scaleStandard Deviation 1.5
Expressive Writing (EW)Change in Religious AffiliationBaseline3.05 units on a scaleStandard Deviation 1.84
Expressive Writing (EW)Change in Religious AffiliationPost Intervention2.79 units on a scaleStandard Deviation 1.65
Self-Affirmation (SA)Change in Religious AffiliationPost Intervention2.71 units on a scaleStandard Deviation 1.94
Self-Affirmation (SA)Change in Religious AffiliationBaseline2.78 units on a scaleStandard Deviation 2.06
Self-Affirmation (SA)Change in Religious Affiliation3 Months3.13 units on a scaleStandard Deviation 1.96
Secondary

Change in Religious Strain

Religious Strain Scale total score obtained by reverse scoring items 1-7 and then summing across the 20 items (range 0-60), higher scores indicate greater religious strain.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in Religious StrainPost Intervention27.52 units on a scaleStandard Deviation 9.52
ControlChange in Religious StrainBaseline29.08 units on a scaleStandard Deviation 8.92
ControlChange in Religious Strain3 Months27.11 units on a scaleStandard Deviation 9.63
Expressive Writing (EW)Change in Religious StrainPost Intervention26.52 units on a scaleStandard Deviation 9.49
Expressive Writing (EW)Change in Religious StrainBaseline27.11 units on a scaleStandard Deviation 10.01
Expressive Writing (EW)Change in Religious Strain3 Months25.44 units on a scaleStandard Deviation 9.31
Self-Affirmation (SA)Change in Religious StrainBaseline32.75 units on a scaleStandard Deviation 9.36
Self-Affirmation (SA)Change in Religious Strain3 Months29.50 units on a scaleStandard Deviation 9.61
Self-Affirmation (SA)Change in Religious StrainPost Intervention31.40 units on a scaleStandard Deviation 10.62
Secondary

Change in Risk Taking

Risk taking impulse will be assessed using the Columbia Card Task. Participants are presented with 32 face-down cards. Some of these cards are gain cards (which add either +10 or +30 points to the participant's total score) and some of these cards are loss cards (which subtract either -250 or -750 points from the participant's total score). On each trial, the participant may turn over as many cards as desired until a loss card is encountered or the participant chooses to not turn over any more cards. As a participant turns over more cards, the probability of encountering a loss card increases. Therefore, turning over more cards constitutes greater risk taking.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: This outcome measure was never collected.

Secondary

Change in Stress

Stress will be assessed using the Perceived Stress Scale (PSS). Participants were asked to respond to the 14-item version. Participants respond to each item on a 0-4 scale and scores are obtained by reversing responses to the 7 positively stated items (items 4,5,6,7,9,10, & 13), and then summing across all scale items. Range = 0-56. Higher scores indicating higher perceived stress.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in StressPost-Intervention27.03 units on a scaleStandard Deviation 9.96
ControlChange in StressBaseline30.25 units on a scaleStandard Deviation 8.62
ControlChange in Stress3 Months28.41 units on a scaleStandard Deviation 10.66
Expressive Writing (EW)Change in StressPost-Intervention24.70 units on a scaleStandard Deviation 9.67
Expressive Writing (EW)Change in StressBaseline29.53 units on a scaleStandard Deviation 8.4
Expressive Writing (EW)Change in Stress3 Months25.88 units on a scaleStandard Deviation 7.77
Self-Affirmation (SA)Change in StressBaseline31.61 units on a scaleStandard Deviation 9.51
Self-Affirmation (SA)Change in Stress3 Months28.69 units on a scaleStandard Deviation 9.01
Self-Affirmation (SA)Change in StressPost-Intervention26.73 units on a scaleStandard Deviation 8.58
Secondary

Change in Victimization

Feelings of victimization are captured using the LGBT Victimization Experiences measure. This questionnaire consists of 10 items. The LGBT victimization scale is rated on a 0 Never to 3 3+ times scale with a total score range 0-30. The total score reflects the amount of victimization one has experienced due to being known or thought to be LGBTQ. Higher scores indicate more negative experiences.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlChange in VictimizationPost-Intervention0.30 units on a scaleStandard Deviation 0.81
ControlChange in VictimizationBaseline1.47 units on a scaleStandard Deviation 2.16
ControlChange in Victimization3 Months0.81 units on a scaleStandard Deviation 1.33
Expressive Writing (EW)Change in Victimization3 Months0.97 units on a scaleStandard Deviation 2.47
Expressive Writing (EW)Change in VictimizationBaseline1.33 units on a scaleStandard Deviation 2.05
Expressive Writing (EW)Change in VictimizationPost-Intervention0.24 units on a scaleStandard Deviation 0.56
Self-Affirmation (SA)Change in Victimization3 Months1.08 units on a scaleStandard Deviation 2.42
Self-Affirmation (SA)Change in VictimizationPost-Intervention0.67 units on a scaleStandard Deviation 1.65
Self-Affirmation (SA)Change in VictimizationBaseline2.56 units on a scaleStandard Deviation 5.42
Secondary

Hopelessness

Hopelessness will be measured using the Beck Hopelessness Scale (BHS). The BHS is a 20-item dichotomous scale (No = 0, Yes = 1). Items 1, 3, 5, 6, 8, 10, 13, 15 and 19 are reverse-scored. The total score is out of 20, where 20 would be the highest score and considered a negative indicator of hopelessness.

Time frame: Baseline, Post Intervention, 3 Months

Population: Data analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlHopelessnessPost-Intervention6.93 units on a scaleStandard Deviation 6.31
ControlHopelessnessBaseline7.00 units on a scaleStandard Deviation 6.08
ControlHopelessness3 Months5.85 units on a scaleStandard Deviation 5.8
Expressive Writing (EW)HopelessnessPost-Intervention4.88 units on a scaleStandard Deviation 4.87
Expressive Writing (EW)HopelessnessBaseline5.14 units on a scaleStandard Deviation 4.28
Expressive Writing (EW)Hopelessness3 Months5.19 units on a scaleStandard Deviation 5.07
Self-Affirmation (SA)HopelessnessBaseline7.44 units on a scaleStandard Deviation 6.07
Self-Affirmation (SA)Hopelessness3 Months7.77 units on a scaleStandard Deviation 7
Self-Affirmation (SA)HopelessnessPost-Intervention7.80 units on a scaleStandard Deviation 6.51
Secondary

Lesbian, Gay, Bisexual (LGB) Identity

LGB identity will be measured using the 'LGB Identity Centrality' instrument.The measure consists of 4 items that are rated on a scale of 1-7. The summed scores have a range of 4-28 and the higher score would indicate a stong agreement (positive) with the centrality of one's LGB identity.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed as intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlLesbian, Gay, Bisexual (LGB) IdentityPost-Intervention19.91 units on a scaleStandard Deviation 5.17
ControlLesbian, Gay, Bisexual (LGB) IdentityBaseline22.44 units on a scaleStandard Deviation 6.08
ControlLesbian, Gay, Bisexual (LGB) Identity3 Months20.74 units on a scaleStandard Deviation 4.92
Expressive Writing (EW)Lesbian, Gay, Bisexual (LGB) IdentityPost-Intervention17.33 units on a scaleStandard Deviation 5.95
Expressive Writing (EW)Lesbian, Gay, Bisexual (LGB) IdentityBaseline18.47 units on a scaleStandard Deviation 5.36
Expressive Writing (EW)Lesbian, Gay, Bisexual (LGB) Identity3 Months17.00 units on a scaleStandard Deviation 5.81
Self-Affirmation (SA)Lesbian, Gay, Bisexual (LGB) IdentityBaseline20.11 units on a scaleStandard Deviation 5.67
Self-Affirmation (SA)Lesbian, Gay, Bisexual (LGB) Identity3 Months18.27 units on a scaleStandard Deviation 7.48
Self-Affirmation (SA)Lesbian, Gay, Bisexual (LGB) IdentityPost-Intervention18.27 units on a scaleStandard Deviation 7.08
Secondary

Perceived Support

Perceived social support is measured using the Multidimensional Scale of Perceived Social Support (MSPSS). The MSPSS is a 12 item instrument that uses a scale 1-7 to rate each item. The scoring is done by taking the average of the items- therefore a score of 7 indicates the highest level of perceived social support.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlPerceived Support3 Months5.12 units on a scaleStandard Deviation 1.39
ControlPerceived SupportBaseline5.11 units on a scaleStandard Deviation 1.3
ControlPerceived SupportPost-Intervention5.10 units on a scaleStandard Deviation 1.08
Expressive Writing (EW)Perceived Support3 Months5.53 units on a scaleStandard Deviation 1.01
Expressive Writing (EW)Perceived SupportPost-Intervention5.34 units on a scaleStandard Deviation 0.93
Expressive Writing (EW)Perceived SupportBaseline5.35 units on a scaleStandard Deviation 0.94
Self-Affirmation (SA)Perceived Support3 Months5.09 units on a scaleStandard Deviation 1.65
Self-Affirmation (SA)Perceived SupportPost-Intervention5.03 units on a scaleStandard Deviation 1.44
Self-Affirmation (SA)Perceived SupportBaseline4.89 units on a scaleStandard Deviation 1.4
Secondary

Rumination

Rumination will be assessed using the Ruminative Response Scale - Brooding Subscale (RRS). This scale is modified from the original measure where only items 5, 10, 13, 15 and 16 are used. Each item is scored by respondents on a scale of 1 to 4. To get the overall score, the 5 items are summed; total scores range from 5-20, with higher scores indicating greater brooding and rumination (related to depression) in an individual.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlRuminationPost-Intervention11.58 units on a scaleStandard Deviation 3.57
ControlRuminationBaseline12.39 units on a scaleStandard Deviation 3.68
ControlRumination3 Months11.44 units on a scaleStandard Deviation 4.86
Expressive Writing (EW)RuminationPost-Intervention11.67 units on a scaleStandard Deviation 3.48
Expressive Writing (EW)RuminationBaseline12.97 units on a scaleStandard Deviation 3.48
Expressive Writing (EW)Rumination3 Months10.81 units on a scaleStandard Deviation 3.81
Self-Affirmation (SA)RuminationBaseline13.03 units on a scaleStandard Deviation 3.55
Self-Affirmation (SA)Rumination3 Months11.81 units on a scaleStandard Deviation 3.62
Self-Affirmation (SA)RuminationPost-Intervention12.10 units on a scaleStandard Deviation 4.41
Secondary

Self Injury.

Self injury behaviors will be assessed with the item that asks: How many times in the past 3 months/past week have you engaged in self-harm behavior (e.g., cutting, biting, burning, hitting self) with the intent of harming, but not killing, yourself? Reported are the frequency of self-harm behaviors/self-injury reported by participants. Original title: Change in Self Injury.

Time frame: Baseline, Post Intervention (day 5), and 3 Months.

Population: Data were analyzed intention to treat.

ArmMeasureGroupValue (MEAN)Dispersion
ControlSelf Injury.Post-Intervention0.12 self-harm behaviorsStandard Deviation 0.48
ControlSelf Injury.Baseline0.61 self-harm behaviorsStandard Deviation 1.5
ControlSelf Injury.3 Months0.26 self-harm behaviorsStandard Deviation 0.71
Expressive Writing (EW)Self Injury.Post-Intervention0.21 self-harm behaviorsStandard Deviation 1.22
Expressive Writing (EW)Self Injury.Baseline1.36 self-harm behaviorsStandard Deviation 5.11
Expressive Writing (EW)Self Injury.3 Months0.97 self-harm behaviorsStandard Deviation 4.45
Self-Affirmation (SA)Self Injury.Baseline0.94 self-harm behaviorsStandard Deviation 2.11
Self-Affirmation (SA)Self Injury.3 Months1.27 self-harm behaviorsStandard Deviation 3.97
Self-Affirmation (SA)Self Injury.Post-Intervention0.07 self-harm behaviorsStandard Deviation 0.25

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026