Gestational Diabetes
Conditions
Brief summary
The overall purpose of this intervention study is to examine whether low-carbohydrate dietary intervention will prevent the development of gestational diabetes mellitus (GDM) in high-risk pregnant women. The results of this study should help further our understanding of how pregnant women can help prevent gestational diabetes mellitus. We hypothesize that a lower carbohydrate diet will prevent the development of GDM.
Interventions
OTHER100 g carbs
Participants will be assigned a diet of 100g carbs max for the day
OTHERMyPlate
40-65% of daily intake is from carbohydrates
Sponsors
State University of New York at Buffalo
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* 18 - 40 years old * BMI \> 30 and/or history of gestational diabetes mellitus * Currently in first trimester of pregnancy with single fetus (e.g. not twins, triplets, etc.) * Newborns of current participants
Exclusion criteria
* Diabetes (types 1 and 2) * History of major chronic disease or blood clotting disorders (e.g., cancer, heart disease, kidney disease, hypertension) * Known fetal anomaly * History of eating disorders * Current use of medications that affect appetite or insulin secretion/sensitivity (e.g. stimulants) * Current use of illegal substances, antipsychotic or opioid substitution medications, alcohol, or tobacco
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Birth Outcome Questionnaire | 24 months | Upon delivery of the baby, a birth outcome questionnaire will be collected which includes questions about the delivery and birth of the baby and a question about gestational diabetes. The answer to gestational diabetes or not will be the measure for the outcome. |
Countries
United States
Outcome results
None listed