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Investigating Temporal Improvements in Survival Following ST-elevation Myocardial Infarction.

Investigating Temporal Improvements in Survival Following ST-elevation Myocardial Infarction: A Causal Mediation Analysis Using the Myocardial Ischaemia National Audit Project, 2004-2013.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03749694
Enrollment
232353
Registered
2018-11-21
Start date
2004-01-01
Completion date
2013-06-30
Last updated
2018-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Myocardial Infarction

Keywords

Acute Myocardial Infarction, mortality, evidence-based care, Myocardial Ischaemia National Audit Project, ST-elevation myocardial infarction

Brief summary

The aim of the study was to use data from the Myocardial Ischaemia National Audit Project (MINAP) to investigate whether temporal improvements in survival were associated with changes in patients' baseline clinical risk or use of guideline-indicated treatments for the management of STEMI, and to determine the extent to which associations explained the temporal improvements in survival.

Interventions

None listed

Sponsors

University of Leeds
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* aged 18 years or more * patients hospitalised with ST-elevation myocardial infarction

Exclusion criteria

* patients hospitalised with phenotypes other than ST-elevation myocardial infarction

Design outcomes

Primary

MeasureTime frame
All cause mortalityone year

Secondary

MeasureTime frame
All cause mortalitysix months

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 20, 2026