NLCR in Prediction of the Grade of Lung Tumor.

Preoperative Neutrophil-lymphocyte Count Ratio in Prediction of the Grade of Lung Tumor.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03749512

Enrollment

400

Registered

2018-11-21

Start date

2014-10-01

Completion date

2018-11-16

Last updated

2018-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung Neoplasm

Keywords

NLCR, The neutrophil-lymphocyte count ratio, Lung Neoplasm

Brief summary

The aim of the study is to assess whether the value of neutrophil-lymphocyte count ratio from the routine preoperative blood test may predict lung tumors' grading.

Detailed description

Lung cancer remains as one of the leading causes of death among oncology patients. Close connection between inflammation and pathogenesis of some neoplasms was determined in a number of studies. Some studies show promise that ratio of neutrophil to lymphocyte count (NLCR) may be recognized as a prognostic marker for several carcinomas: renal, lung and colorectal. The aim of the study is to assess whether the value of neutrophil-lymphocyte count ratio from the routine preoperative blood test may predict lung tumors' grading. During routine preoperative blood tests complete blood count is done and NLCR, WBC, neutrophil and lymphocyte count is noted. After the thoracic surgery intervention and histopathological examination grading of lung tumor is noted.

Interventions

DIAGNOSTIC_TESTComplete blood count

During routine preoperative blood test complete blood count is taken.

OTHERHistopathological examination

Routine postoperative histopathological examination of lung tumor.

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* consecutive thoracic surgery patients with lung cancer grading confirmed by histopathology postoperatively * preoperative routine complete blood count analysis

Exclusion criteria

* infectious disease * pregnancy * autoimmunologic disease * other known conditions or treatments that may influence the blood count (seropositivity for HIV, chemotherapy, and corticotherapy)

Design outcomes

Primary

Measure	Time frame	Description
Neutrophil-lymphocyte count ratio	From October 1, 2014 to October 15, 2018	Neutrophil-lymphocyte count ratio is measured during routine preoperative blood tests.

Secondary

Measure	Time frame	Description
Neutrophil count	From October 1, 2014 to October 15, 2018	Neutrophil count is measured during routine preoperative blood tests.
Lymphocyte count	From October 1, 2014 to October 15, 2018	Lymphocyte count is measured during routine preoperative blood tests.
Leucocyte count	From October 1, 2014 to October 15, 2018	Leucocyte count is measured during routine preoperative blood tests.

Countries

Poland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026