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Effects of Supervised Exercise on Physical Health and Quality of Life Among Older HIV Adults

Effects of Supervised Exercise Program on Physical Health and Quality of Life Among Older Adults Living With HIV in Hong Kong

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03748797
Enrollment
21
Registered
2018-11-21
Start date
2017-11-01
Completion date
2018-03-31
Last updated
2018-11-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HIV/AIDS

Keywords

HIV, exercise, aging, physical health, quality of life

Brief summary

The effects of exercise for older HIV-infected adults have not been well studied, especially in Chinese population. This study aimed to investigate the effect of supervised exercise on physical health and quality of life among older people living with HIV (PLWH) in Hong Kong. HIV-infected adults were recruited from a community-based Non-Governmental Organization (NGO) for HIV patient services. Participants were randomized into exercise group or control group. The participants in exercise group performed an 8-week moderate intensity supervised exercise program. In the control group, participants were not given any supervised exercises. They were advised to continue their routine daily activities and self exercises. Outcomes were measured for both groups at baseline and after 8 weeks. Primary outcomes: grip strength, 30 seconds chair stand, 6 minutes-walk test and Short Form-36 questionnaire (SF-36). Secondary outcome: Subjective improvement At the end of the program, all participants from exercise group were interviewed individually by principle investigator to allow feedbacks.

Detailed description

It is a randomized controlled trial. HIV-infected adults were recruited from a community-based Non-Governmental Organization (NGO) for HIV patient services.They were randomized into exercise group or control group by drawing lots which contained equal number of orange balls (exercise) and white balls (control) The participants in exercise group performed an 8-week, 2 times/week supervised exercise program in the community day center of the recruiting NGO. Exercise sessions were organized in a group of 2 to 3 participants. The exercises were supervised by a registered physiotherapist to ensure exercise safety and quality. Exercise intensity was moderate. We monitored the heart rate of participants during exercise and maintained around 50% to 70% of maximum heart rate. Blood pressure and oxygen saturation were also checked for safety purposes. The mode of exercise was combined aerobic and resistance training. It involved upper and lower limbs cycling, treadmill walking, multi-gym strengthening, stepper exercise, dumb bell and squatting exercise. The duration for each exercise session was around 45 minutes. Duration and intensity of exercises were adjusted depending on the tolerance and physical capacity of each participant. In the control group, participants were not given any supervised exercises. They were advised to continue their routine daily activities and self exercises. Control group participants were allowed to join into the same training program after the research had finished. Outcomes were measured for both groups at baseline and after 8 weeks in the same community day center. A research assistant who was blinded for the participants grouping was responsible for data collection. Physical health parameters included grip strength, 30 seconds chair stand and 6 minutes-walk test. Health related quality of life was measured by Short Form-36 questionnaire (SF-36). Subjective improvement was taken in form of Likert scale, from -100% to +100% with 10% interval in each possible response. At the end of the program, all participants from exercise group were interviewed individually by principle investigator to allow feedbacks.

Interventions

OTHERModerate intensity exercise training under supervision

Upper and lower limbs cycling, treadmill walking, multi-gym strengthening, stepper exercise, dumb bell and squatting exercise

Sponsors

The University of Hong Kong
CollaboratorOTHER
The Society for AIDS Care
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Masking description

A research assistant who was blinded for the participants grouping was responsible for data collection.

Intervention model description

Exercise group: Performed an 8-week, 2 times/week exercise training (moderate intensity) under physiotherapist supervision. Control group: No supervised exercise training given. Participants were advised to continue their routine daily activities and self exercises if they have.

Eligibility

Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
No

Inclusion criteria

1. Participants with HIV age \> 50, treating with antiretroviral therapy 2. No contraindication to moderate intensity exercise 3. Independent Outdoor walker without assistance 4. Sedentry participants who have not received any structural / supervised exercise program in the past 1 year

Exclusion criteria

1. Age \<50 2. Unstable or unfit for exercise 3. Wheelchair user or assisted walker 4. Already had regular exercise habit or under structural exercise program in the past 1 year

Design outcomes

Primary

MeasureTime frameDescription
Change of SF-36 scoresChange from Baseline SF-36 scores at 8 weeksShort Form 36 (SF-36) questionnaire is used to assess health related quality of life
Change of Grip strengthChange from Baseline grip strength at 8 weeksMaximum grip strength of the participant in kg
Change of 30 seconds chair standChange from Baseline performance at 8 weeksNumber of times that the participant stand up and sit down within 30 seconds
Change of 6 minutes walk testChange from Baseline performance at 8 weeksThe distance (in meters) which the participant is able to walk in 6 minutes

Secondary

MeasureTime frameDescription
Subjective improvementSubjective change after 8 weeks compare to baselineSubjective physical improvement reported by participant (from -100% to +100%)

Countries

Hong Kong

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026