Iron-deficiency
Conditions
Brief summary
the investigators will compare the response to iron deficiency anemia to lactoferrin plus ferrous poly maltose versus ferrous poly maltose in Children With Chronic Tonsillitis
Detailed description
Iron deficiency is frequently present with chronic inflammatory disease.(1) Iron deficiency anemia results from decreased body's iron content due to blood loss, poor dietary iron intake, malabsorption, or increased iron requirement. Immune activation drives a diversion of iron to storage sites, particularly the mononuclear phagocytes system in liver and spleen leads to poor hemoglobinization and anemia. Iron deficiency and immune activation lead to disturbances of iron homeostasis.(2) this trial will compare the response to iron deficiency anemia to lactoferrin plus ferrous poly maltose versus ferrous poly maltose in Children With Chronic Tonsillitis
Interventions
DRUGLactoferrin
lactoferrin 100 mg per day plus ferric hydroxide polymaltose 6 mg /kilogram of Elemental iron
DRUGFerric Hydroxide Polymaltose
group 2 will receive ferric hydroxide polymaltose 6 mg /kilogram of elemental iron
Sponsors
South Valley University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
3 Years to 17 Years
Healthy volunteers
No
Inclusion criteria
* children 3-17 years old with chronic tonsillitis
Exclusion criteria
* no other causes of Iron Deficiency Anemia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Increase in blood hemoglobin | 1,3 months | mean difference in hemoglobin level between pre treatment and post treatment. mean difference in hemoglobin level between pre treatment and post treatment. |
| Increase in serum ferritin | 3 months | mean difference in ferritin level between pre treatment and post treatment. |
Countries
Egypt
Contacts
Primary Contactshimaa Ahmed, Lecturer
Outcome results
None listed