Prospective Evaluation of the Biomechanical Properties of the Thoracic Aorta Coupling Magnetic Resonance Imaging and In-vitro Elasticity Tests in Patients With Ascending Aortic Aneurysm

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03746964

Acronym

MECATHOR

Enrollment

200

Registered

2018-11-20

Start date

2018-12-17

Completion date

2027-02-28

Last updated

2026-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patient With Ascending Aortic Aneurysm With Surgical Indication for Replacement

Brief summary

The biomechanical properties of the aorta are currently poorly understood. A better understanding would optimize surgical indications and monitoring techniques for patients with thoracic aortic aneurysms.

Interventions

PROCEDURECardiac MRI

Preoperative cardiac MRI

OTHERin-vitro elasticity tests

in-vitro elasticity tests performed on a segment of ascending aorta collected during surgery

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Person who has given oral consent * Patient with ascending aortic aneurysm with surgical indication for replacement * Age \> 18 years old * Scheduled surgery

Exclusion criteria

* Person not affiliated to the national health insurance system * Protected adult * Pregnant or breastfeeding woman * MRI Contraindication * Emergency surgical procedure

Design outcomes

Primary

Measure	Time frame
aortic compliance by cardiac MRI	Before surgery
In-vitro testing of the elasticity of the aortic wall fragment collected during surgery.	through study completion, an average of 12 months

Countries

France

Contacts

Primary ContactComlan BLITTI

comlanmawuko.blitti@chu-dijon.fr+33 3 80 29 33 52

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026