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Development and Testing of a Just-in-Time Adaptive Smart Phone Intervention to Reduce Drinking Among Homeless Adults

Development and Testing of a Just-in-Time Adaptive Smart Phone Intervention

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03746808
Acronym
Smart-T
Enrollment
119
Registered
2018-11-20
Start date
2019-02-14
Completion date
2022-05-31
Last updated
2022-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol Use Disorder, Homelessness, Treatment

Brief summary

Homeless adults are 8 times as likely to be alcohol dependent compared with adults in the general population, yet few studies have examined the precipitants of alcohol use in this vulnerable population. Ecological momentary assessments (EMAs) that involve repeated assessment of thoughts/mood/behaviors (e.g., via smart phone) is currently the most accurate way to assess individuals in real-time in their natural environments. Advances in smartphone technology also allow for the collection of continuous geolocation and other passive sensing data. Thus, researchers can now link environmental risks and protective factors to outcomes, without reliance on subjective reporting alone. Building on prior work, this study will use a three-phase study to develop and test a just in time adaptive intervention to reduce alcohol use in homeless men and women. Phase I will use smartphones and passive sensing technologies to monitor geolocation, psychosocial variables (e.g., stress, affect, urge to drink), and alcohol use in a group of 80 homeless adults with an AUD who are receiving shelter-based treatment. Phase I will identify environmental (i.e., geolocation), cognitive, and behavioral antecedents of alcohol use over 4 weeks. Phase II will use this information to create a risk algorithm and tailored treatment messages that anticipate and intervene to prevent drinking. The resulting app will assess imminent risk of alcohol use after each EMA and will deliver relevant treatment messages that match a person's current risk factors. Phase III will test the feasibility, acceptability and preliminary efficacy of the app in a sample of 40 homeless adults with an AUD who receive the EMA plus treatment messages over 4 weeks. Drinking will be determined via self-report, supplemented by a transdermal alcohol sensor (i.e., SCRAM) worn by participants. This project will be the first to combine geolocation and psychosocial variables to identify real-time antecedents of drinking. If effective, this smartphone app could significantly improve treatment engagement, drinking outcomes, and quality of life among homeless adults with alcohol use disorders.

Detailed description

An estimated 6.2% of US adults will be homeless at some point in their lifetime. Homeless adults have higher rates of disease, greater risk of interpersonal violence, shorter life expectancies, and disproportionately higher health care utilization and costs compared to housed individuals. A significant contributor to morbidity and mortality among homeless adults is the high prevalence of alcohol use. Approximately 33% of homeless adults have current alcohol dependence, a rate nearly 8 times that of the general population. Although shelter-based treatments are common, compliance is typically poor. Identifying factors that influence alcohol use would significantly improve the ability to develop effective interventions and engage homeless adults in treatment. Relatively little is known about the environmental, cognitive, and behavioral antecedents of alcohol use in homeless adults. Like other subgroups, alcohol use has most often been examined using traditional lab/clinic based assessment methods that are not well suited to capturing the complicated street-level interactions experienced by most homeless adults. Traditional assessment methodologies may also provide biased and/or inaccurate estimates due to recall biases and errors in memory, particularly in this complicated population. Ecological momentary assessment (EMA), in which handheld devices (e.g., smartphones) are used to capture moment-to-moment experience, is currently the most accurate way to measure phenomena in natural settings. Additionally, recent technological advances have made it possible to collect continuous geolocation data alongside EMA. Researchers can now link environmental risks and protective factors to outcomes, without reliance on subjective reporting alone. This pilot study will develop and test a just-in-time adaptive intervention to reduce alcohol use among homeless adults. Phase I will use smartphones and passive sensing to monitor geolocation, psychosocial variables (e.g., stress, urge to drink), and alcohol use in a group of 80 homeless adults enrolled in shelter-based treatment for an AUD. Phase II will use this information to create a risk algorithm and tailored treatment messages that anticipate and intervene to prevent alcohol use. Phase II will modify an existing app, previously validated for smoking cessation, to create the intervention. Phase III will pilot test the newly developed app for utility, satisfaction, and preliminary effectiveness in a group of 40 homeless adults with an AUD who are enrolled in shelter-based treatment. Alcohol consumption will be validated via a transdermal alcohol sensor (i.e., SCRAM) worn by participants in Phases I and III. The central hypothesis is that alcohol use is strongly affected by moment-to-moment risk and protective factors. This study will be able to use EMAs to identify and automatically intervene during moments when people are at high risk for drinking. This hypothesis is based on preliminary findings among homeless, justice-involved, and socioeconomically disadvantaged safety-net hospital patients. If effective, this smartphone app could significantly improve treatment engagement, drinking outcomes, and quality of life among homeless adults with AUDs. This project will: 1. Use EMA to identify environmental (i.e., geolocation), cognitive, and behavioral antecedents of alcohol use among 80 homeless adults with an AUD who are receiving shelter-based treatment. 2. Informed by Aim 1 findings, develop a just-in-time adaptive intervention to reduce alcohol use, including an alcohol use risk algorithm and corresponding theory-based treatment messages. 3. Examine feasibility, acceptability, and preliminary effectiveness of a just-in-time adaptive smartphone app among 40 homeless adults with an AUD who are receiving shelter-based treatment.

Interventions

BEHAVIORALEMA + App/Treatment Messages

This study will develop and test a just-in-time adaptive intervention to reduce alcohol use among homeless adults. Phase I will use smartphones and passive sensing to monitor geolocation, psychosocial variables (e.g., stress, urge to drink), and alcohol use in a group of 80 homeless adults with an AUD who are enrolled in shelter-based treatment. Phase II will use this information to create a risk algorithm and tailored treatment messages that anticipate and intervene to prevent alcohol use.

Sponsors

University of Oklahoma
CollaboratorOTHER
University of North Texas Health Science Center
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* Score ≥ 8 on the AUDIT * Report consuming ≥ 1 drink of alcohol in the past week * Receiving treatment at Metrocare; * Willing and able to complete the baseline and follow-up visits; * Score ≥ 4 on the REALM-SF, indicating \> 6th grade English literacy level * Score ≥ 24 on the Mini-Mental State Exam

Exclusion criteria

* Circulation problems, neuropathy, deep vein thrombosis, leg ulcers, tendonitis, diabetes, pregnancy, history of swelling or nickel or other metal allergies that would prohibit wearing the SCRAM ankle bracelet. * Self-reported discomfort wearing an alcohol sensing bracelet for 4 weeks. * Previously participated in Phase I (for Phase III recruitment).

Design outcomes

Primary

MeasureTime frameDescription
Satisfaction With App Treatment Messages4 weeksSatisfaction with app on self-reported questions at follow-up (1-5 scale where 1 = Not at all; and 5 = Extremely)

Secondary

MeasureTime frameDescription
Number of Drinking Days4 weeksNumber of drinking days (number of days with any self-reported drinking out of 28 days)
Number of Heavy Drinking Days4 weeksNumber of drinking days (number of days with self-reported \>4 drinks for men; \>3 drinks for women out of 28 days)

Countries

United States

Participant flow

Participants by arm

ArmCount
EMA Only
Phase I will use smartphones and passive sensing to monitor geolocation, psychosocial variables (e.g., stress, urge to drink), and alcohol use in a group of 80 homeless adults with an AUD who are receiving shelter-based treatment. EMA + App/Treatment Messages: This study will develop and test a just-in-time adaptive intervention to reduce alcohol use among homeless adults. Phase I will use smartphones and passive sensing to monitor geolocation, psychosocial variables (e.g., stress, urge to drink), and alcohol use in a group of 80 homeless adults with an AUD who are enrolled in shelter-based treatment. Phase II will use this information to create a risk algorithm and tailored treatment messages that anticipate and intervene to prevent alcohol use.
78
EMA + App/Treatment Messages
Phase III will pilot test the newly developed app for utility, satisfaction, and preliminary effectiveness in a group of 40 homeless adults with an AUD who are receiving shelter-based treatment. The investigators will compare Phase III participants (i.e., received Metrocare, EMAs, and tailored treatment messages) to Phase I participants (i.e., received Metrocare and EMAs only) to examine the preliminary effectiveness of the app. EMA + App/Treatment Messages: This study will develop and test a just-in-time adaptive intervention to reduce alcohol use among homeless adults. Phase I will use smartphones and passive sensing to monitor geolocation, psychosocial variables (e.g., stress, urge to drink), and alcohol use in a group of 80 homeless adults with an AUD who are enrolled in shelter-based treatment. Phase II will use this information to create a risk algorithm and tailored treatment messages that anticipate and intervene to prevent alcohol use.
41
Total119

Baseline characteristics

CharacteristicEMA + App/Treatment MessagesTotalEMA Only
Age, Categorical
<=18 years
0 Participants0 Participants0 Participants
Age, Categorical
>=65 years
0 Participants0 Participants0 Participants
Age, Categorical
Between 18 and 65 years
41 Participants119 Participants78 Participants
Age, Continuous45.2 years
STANDARD_DEVIATION 11.5
46.1 years
STANDARD_DEVIATION 10
46.6 years
STANDARD_DEVIATION 9.2
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants1 Participants1 Participants
Race (NIH/OMB)
Asian
0 Participants0 Participants0 Participants
Race (NIH/OMB)
Black or African American
10 Participants32 Participants22 Participants
Race (NIH/OMB)
More than one race
2 Participants4 Participants2 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants0 Participants0 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants2 Participants2 Participants
Race (NIH/OMB)
White
29 Participants80 Participants51 Participants
Region of Enrollment
United States
41 Participants119 Participants78 Participants
Sex: Female, Male
Female
8 Participants20 Participants12 Participants
Sex: Female, Male
Male
33 Participants99 Participants66 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
deaths
Total, all-cause mortality
0 / 780 / 41
other
Total, other adverse events
0 / 780 / 41
serious
Total, serious adverse events
0 / 780 / 41

Outcome results

Primary

Satisfaction With App Treatment Messages

Satisfaction with app on self-reported questions at follow-up (1-5 scale where 1 = Not at all; and 5 = Extremely)

Time frame: 4 weeks

Population: People who attended 4-week follow-up visit

ArmMeasureGroupValue (MEAN)Dispersion
EMA + App/Treatment MessagesSatisfaction With App Treatment MessagesHow useful was the Sober Tips feature?3.9 score on a scaleStandard Deviation 1
EMA + App/Treatment MessagesSatisfaction With App Treatment MessagesWould you be interested in using this smart phone app in the future if needed?3.8 score on a scaleStandard Deviation 1.5
EMA + App/Treatment MessagesSatisfaction With App Treatment MessagesHow helpful has the smart phone application been in helping you to reduce alcohol consumption?3.6 score on a scaleStandard Deviation 1.1
EMA + App/Treatment MessagesSatisfaction With App Treatment MessagesHow likely would you be to recommend this smart phone app to a friend?4.0 score on a scaleStandard Deviation 1.4
Secondary

Number of Drinking Days

Number of drinking days (number of days with any self-reported drinking out of 28 days)

Time frame: 4 weeks

Population: Participants available for analysis

ArmMeasureValue (MEAN)Dispersion
EMA OnlyNumber of Drinking Days13.9 Number of drinking daysStandard Deviation 2.65
EMA + App/Treatment MessagesNumber of Drinking Days11.2 Number of drinking daysStandard Deviation 2.6
Secondary

Number of Heavy Drinking Days

Number of drinking days (number of days with self-reported \>4 drinks for men; \>3 drinks for women out of 28 days)

Time frame: 4 weeks

Population: Participants available for analysis

ArmMeasureValue (MEAN)Dispersion
EMA OnlyNumber of Heavy Drinking Days3.42 Number of heavy drinking daysStandard Deviation 1.78
EMA + App/Treatment MessagesNumber of Heavy Drinking Days3.64 Number of heavy drinking daysStandard Deviation 1.73

Source: ClinicalTrials.gov · Data processed: Apr 17, 2026