Immunogenicity and Safety of Tetravalent Dengue Vaccine Candidate (TDV) in Flavivirus-Naïve and Dengue-Immune Adults

An Open-Label, Phase 2 Trial to Investigate the Humoral and Cell-Mediated Immune Responses and Safety of a Tetravalent Dengue Vaccine Candidate (TDV) Administered Subcutaneously in Flavivirus-Naïve and Dengue-Immune Healthy Adults

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03746015

Enrollment

Registered

2018-11-19

Start date

2018-12-28

Completion date

2021-03-01

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dengue Fever

Keywords

Vaccine

Brief summary

The purpose of this study is to assess the neutralizing antibody response against each dengue serotype post-vaccination.

Detailed description

The vaccine being tested in this study is Takeda's Tetravalent Dengue Vaccine Candidate (TDV). TDV is being tested to protect people against dengue fever. This study will look at the immunogenicity and safety of TDV in flavivirus-naïve and dengue-immune adults. The study will enroll approximately 44 patients. Participants will be categorized into two groups based on results from serological testing performed by the trial center outside the scope of this trial (up to 70 days \[10 weeks\] prior to Day 1 \[Month 0\]): Group 1: Flavivirus-Naïve Participants Group 2: Dengue-Immune Participants All participants will receive subcutaneous injection of TDV on Day 1 (Month 0) and Day 90 (Month 3). This trial will be conducted in the United States. The overall time to participate in this study is 12 months. Participants will make multiple visits to the clinic, and 9 months after last dose of study drug for a follow-up assessment.

Interventions

BIOLOGICALTDV

TDV subcutaneous injection comprised of 1 molecularly characterized, attenuated dengue virus strain, and 3 chimeric dengue virus strains with potencies of not less than 3.3, 2.7, 4.0, and 4.5 log10 plaque forming units (PFU) per dose of TDV-1, TDV-2, TDV-3, and TDV-4, respectively.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

1. Who are in good health at the time of entry into the trial as determined by medical history, physical examination (including vital signs) and clinical judgment of the investigator. 2. Group 1 only: immunologically naïve to dengue, Zika, Yellow Fever (YF), Japanese Encephalitis (JE), West Nile (WN) (based on negative results for detection of anti-DENV, anti-Zika, anti-YF, anti-JE, anti-WN antibodies) as documented by serological testing performed by the trial center outside the scope of this trial (up to 70 days \[10 weeks\] prior to Day 1 \[Month 0\]). 3. Group 2 only: serology consistent with primary infection with either DENV-1 or DENV-3 (defined as detectable neutralizing antibodies against DENV-1 or DENV-3 only, or titers for DENV-1 or DENV-3 ≥4-times higher than titers for the 2 other dengue serotypes) as documented by serological testing performed by the trial center outside the scope of this trial (up to 70 days \[10 weeks\] prior to Day 1 \[Month 0\]).

Exclusion criteria

1. Has clinically active significant infection (as assessed by the investigator) or body temperature ≥38°C (100.4°F) within 3 days of the intended date of vaccination. 2. Has history of progressive or severe neurologic disorder, seizure disorder or neuro-inflammatory disease (eg, Guillain-Barré syndrome). 3. Known or suspected impairment/alteration of immune function including: 1. Chronic use of oral steroids (equivalent to 20 mg/day prednisone ≥12 weeks and/or ≥2 mg/kg body weight/day prednisone ≥2 weeks) within 60 days prior to Day 1 (Month 0) (use of inhaled, intranasal, or topical corticosteroids is allowed). 2. Receipt of parenteral steroids (equivalent to 20 mg/day prednisone ≥12 weeks and/or ≥2 mg/kg body weight/day prednisone ≥2 weeks) within 60 days prior to Day 1 (Month 0). 3. Administration of immunoglobulins and/or any blood products within 3 months prior to Day 1 (Month 0) or planned administration during the trial. 4. Receipt of immunostimulants within 60 days prior to Day 1 (Month 0). 5. Immunosuppressive therapy such as anti-cancer chemotherapy or radiation therapy within 6 months prior to Day 1 (Month 0). 6. Known Human Immunodeficiency Virus (HIV) infection or HIV-related disease. 7. Hepatitis C virus infection. 8. Genetic immunodeficiency. 4. Has planned vaccination (during the trial conduct) against any non-dengue flavivirus (eg, Zika, YF, JE, WN, tick-borne encephalitis, or Murray-Valley encephalitis). 5. Planned travel (during the trial conduct) to any area endemic for dengue.

Design outcomes

Primary

Measure	Time frame	Description
Geometric Mean Titers (GMT) of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 15	Day 15	GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by microneutralization test 50% (MNT50).
GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 30 (Month 1)	Day 30 (Month 1)	GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.
GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 60 (Month 2)	Day 60 (Month 2)	GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.
GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 90 (Month 3)	Day 90 (Month 3)	GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.
GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 105	Day 105	GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.
GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 120 (Month 4)	Day 120 (Month 4)	GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.
GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 150 (Month 5)	Day 150 (Month 5)	GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.
GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 180 (Month 6)	Day 180 (Month 6)	GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.
GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 270 (Month 9)	Day 270 (Month 9)	GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.
GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 360 (Month 12)	Day 360 (Month 12)	GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.

Secondary

Measure	Time frame	Description
Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	Days 30 (Month 1), 90 (Month 3), 120 (Month 4), 180 (Month 6), 360 (Month 12)	IFN-γ ELISpot response \>3 times higher compared with baseline (no peptide) and ≥5 spots per 10\^6 peripheral blood mononuclear cells (PBMCs) was defined as cellular immune response. Cellular immune response to any peptide pool was reported. The peptide pools included pre-membrane envelope (prME), capsid (C), non-structural proteins (NS): NS1, NS2, NS3, NS4 and NS5 for DENV-1, DENV-2, DENV-3 and DENV-4.
Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	Days 30 (Month 1), 90 (Month 3), 120 (Month 4), 180 (Month 6), 360 (Month 12)	The magnitude of cellular immune response was assessed by the number of SFC/10\^6 PBMCs. IFN-γ ELISpot response \>3 times higher compared with baseline (no peptide) and ≥5 spots per 10\^6 PBMCs was defined as cellular immune response. Cellular immune response to any peptide pool was reported. The peptide pools included prME, C, NS1, NS2, NS3, NS4 and NS5 for DENV-1, DENV-2, DENV-3 and DENV-4.
Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	Days 15, 30 (Month 1), 90 (Month 3), 105, 120 (Month 4), and 360 (Month 12)	Phenotype characterization of cellular immune response was performed in a subset of participants with IFN- γ ELISPOT responses \>50 SFC/10\^6 cells and availability of sufficient cells. Markers included cluster of differentiation (CD) 4, CD8, IFN-γ, tumor necrosis factor-alpha (TNF-α) and interleukin-2 (IL-2). The peptide pools included C, NS1, NS2/4, NS3, NS5 for DENV-2 and prME for DENV-1, DENV-2, DENV-3 and DENV-4.
Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	Days 15, 30 (Month 1), 90 (Month 3), 105, 120 (Month 4), and 360 (Month 12)	Phenotype characterization of cellular immune response was performed in a subset of participants with IFN- γ ELISPOT responses \>50 SFC/10\^6 cells and availability of sufficient cells. Markers included CD4, CD8, IFN-γ, tumor necrosis factor-alpha (TNF-α) and interleukin-2 (IL-2). The peptide pools included C, NS1, NS2/4, NS3, NS5 for DENV-2 and prME for DENV-1, DENV-2, DENV-3 and DENV-4.
Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Days 6, 9, 12, 15, 30 (Month 1), 90 (Month 3), 96, 99, 102, 105, 120 (Month 4)	Vaccine viremia was assessed for each of the four vaccine strain serotypes: TDV-1, TDV-2, TDV-3 and TDV-4. Vaccine viral ribonucleic acid (RNA) was detected by a quantitative reverse transcription-polymerase chain reaction (qRT-PCR) assay. Percentages were rounded off to the nearest decimal place.
Duration of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Up to Day 120 (Month 4)	The duration of vaccine viremia for each vaccine strain was defined as the date when vaccine viremia was last detected (positive result) to date when vaccine viremia was first detected (positive result) + 1 day. It was assessed for each of the four vaccine strains: TDV-1, TDV-2, TDV-3 and TDV-4. Vaccine viral RNA was detected by qRT-PCR assay. Safety Analysis Set included all participants who received at least 1 dose of trial vaccine.
Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Days 6, 9, 12, and 15	Vaccine viremia was assessed for each of the four vaccine strain serotypes: TDV-1, TDV-2, TDV-3 and TDV-4. Vaccine viral RNA was detected by qRT-PCR assay.
Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	Within 7 days after each of the vaccine dose given on Day 1 (Month 0) and 90 (Month 3)	Solicited local AEs (at injection site) were collected by participants using diary cards within 7 days after vaccination and included injection site pain \[Grade 0 (no pain), 1 (mild: no interference with daily activity), 2 (moderate: interference with daily activity with or without treatment) and 3 (severe: prevents daily activity with or without treatment)\], injection site erythema \[Grade 0 (\<25 mm), 1 (25 - ≤ 50 mm), 2 (\>50 - ≤ 100 mm), 3 (\> 100 mm)\] and injection site swelling \[Grade 0 (\<25 mm), 1 (25 - ≤ 50 mm), 2 (\>50 - ≤ 100 mm), 3 (\> 100 mm)\]. Only categories for which there was at least 1 participant are reported.
Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	Within 14 days after each of the vaccine dose given on Day 1 (Month 0) and 90 (Month 3)	Solicited systemic AEs were collected by participants using diary cards within 14 days after vaccination and will include fever, headache, asthenia, malaise and myalgia. Severity grades are: Grade 0: none, Grade 1: mild (no interference with daily activity), Grade 2: moderate (interference with daily activity with or without treatment), Grade 3: severe (prevents normal daily activity with or without treatment). A systemic AE of fever (defined as body temperature ≥ 100.4°F regardless of method taken) was derived from a daily temperature reading recorded within 14 days after vaccination. Only categories for which there was at least 1 participant are reported.
Percentage of Participants With at Least One Unsolicited Adverse Events (AEs) Following Each Vaccination	Up to 28 days (day of vaccination + 27 days) after administration of each vaccine dose given on Day 1 (Month 0) and 90 (Month 3)	An AE is defined as any untoward medical occurrence in a clinical investigation participant administered a study vaccine; it does not necessarily have to have a causal relationship with study vaccine administration.
Percentage of Participants With Serious Adverse Events (SAEs)	From first vaccination (Day 1) through end of study (Day 360 [Month 12])	A SAE is defined as any untoward medical occurrence or effect that at any dose results in death, is life-threatening, requires inpatient hospitalization or prolongation of existing hospitalization, results in persistent or / significant disability / incapacity, is a congenital anomaly / birth defect or is medically important due to other reasons than the aforementioned criteria.
Percentage of Participants With Medically Attended AEs (MAAEs)	From first vaccination (Day 1) through end of study (Day 360 [Month 12])	MAAEs was defined as AEs leading to a medical visit to or by a healthcare professional, including visits to an emergency department, but not fulfilling seriousness criteria.

Countries

United States

Participant flow

Recruitment details

Participants took part in the study at 2 investigative sites in the United States from 28 December 2018 to 1 March 2021.

Pre-assignment details

Healthy participants were enrolled in this study to receive Tetravalent Dengue Vaccine (TDV) on Days 1 and 90. One participant did not meet the randomization criteria and was not allocated to any of the pre-defined study groups and was excluded from all analyses except safety analysis.

Participants by arm

Arm	Count
TDV: Flavivirus-naïve TDV 0.5 mL, SC injection, once on Day 1 (first dose) and then on Day 90 (second dose). Participants who were flavivirus-naïve were included in this group.	21
TDV: DENV Immune: DENV-1 Positive TDV 0.5 mL, SC injection, once on Day 1 (first dose) and then on Day 90 (second dose). Participants with serology consistent with primary infection by DENV-1 were included in this group.	4
TDV: DENV Immune: DENV-3 Positive TDV 0.5 mL, SC injection, once on Day 1 (first dose) and then on Day 90 (second dose). Participants with serology consistent with primary infection by DENV-3 were included in this group.	3
Total	28

Withdrawals & dropouts

Period	Reason	FG000	FG001	FG002
Overall Study	Withdrawal of Consent	1	0	0

Baseline characteristics

Characteristic	TDV: Flavivirus-naïve	Total	TDV: DENV Immune: DENV-3 Positive	TDV: DENV Immune: DENV-1 Positive
Age, Continuous	33.57 years	34.96 years	35.00 years	42.25 years
Body Mass Index (BMI)	24.74 kilogram per meter square (kg/m^2)	24.68 kilogram per meter square (kg/m^2)	25.90 kilogram per meter square (kg/m^2)	23.48 kilogram per meter square (kg/m^2)
Ethnicity (NIH/OMB) Hispanic or Latino	0 Participants	0 Participants	0 Participants	0 Participants
Ethnicity (NIH/OMB) Not Hispanic or Latino	21 Participants	27 Participants	3 Participants	3 Participants
Ethnicity (NIH/OMB) Unknown or Not Reported	0 Participants	1 Participants	0 Participants	1 Participants
Height	169.18 centimeter (cm)	170.56 centimeter (cm)	174.33 centimeter (cm)	175.01 centimeter (cm)
Race (NIH/OMB) American Indian or Alaska Native	0 Participants	0 Participants	0 Participants	0 Participants
Race (NIH/OMB) Asian	2 Participants	5 Participants	2 Participants	1 Participants
Race (NIH/OMB) Black or African American	1 Participants	1 Participants	0 Participants	0 Participants
Race (NIH/OMB) More than one race	0 Participants	0 Participants	0 Participants	0 Participants
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	1 Participants	1 Participants	0 Participants	0 Participants
Race (NIH/OMB) Unknown or Not Reported	0 Participants	0 Participants	0 Participants	0 Participants
Race (NIH/OMB) White	17 Participants	21 Participants	1 Participants	3 Participants
Region of Enrollment United States	21 Participants	28 Participants	3 Participants	4 Participants
Sex: Female, Male Female	10 Participants	12 Participants	0 Participants	2 Participants
Sex: Female, Male Male	11 Participants	16 Participants	3 Participants	2 Participants
Weight	71.54 kilogram (kg)	72.4 kilogram (kg)	79.15 kilogram (kg)	71.86 kilogram (kg)

Adverse events

Event type	EG000 affected / at risk	EG001 affected / at risk	EG002 affected / at risk	EG003 affected / at risk
deaths Total, all-cause mortality	0 / 22	0 / 4	0 / 3	0 / 1
other Total, other adverse events	22 / 22	4 / 4	3 / 3	0 / 1
serious Total, serious adverse events	1 / 22	1 / 4	0 / 3	0 / 1

Outcome results

Primary

Geometric Mean Titers (GMT) of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 15

GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by microneutralization test 50% (MNT50).

Time frame: Day 15

Population: Per Protocol Set (PPS) included all participants in the Full Analysis Set (FAS) who had no major protocol violations.

Arm	Measure	Group	Value (GEOMETRIC_MEAN)
TDV: Flavivirus-naïve	Geometric Mean Titers (GMT) of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 15	DENV-1	58.9 titer
TDV: Flavivirus-naïve	Geometric Mean Titers (GMT) of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 15	DENV-2	11.2 titer
TDV: Flavivirus-naïve	Geometric Mean Titers (GMT) of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 15	DENV-3	42.1 titer
TDV: Flavivirus-naïve	Geometric Mean Titers (GMT) of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 15	DENV-4	19.7 titer
TDV: DENV Immune: DENV-1 Positive	Geometric Mean Titers (GMT) of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 15	DENV-4	1996.4 titer
TDV: DENV Immune: DENV-1 Positive	Geometric Mean Titers (GMT) of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 15	DENV-1	15325.2 titer
TDV: DENV Immune: DENV-1 Positive	Geometric Mean Titers (GMT) of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 15	DENV-3	2468.7 titer
TDV: DENV Immune: DENV-1 Positive	Geometric Mean Titers (GMT) of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 15	DENV-2	5200.2 titer
TDV: DENV Immune: DENV-3 Positive	Geometric Mean Titers (GMT) of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 15	DENV-4	4909.2 titer
TDV: DENV Immune: DENV-3 Positive	Geometric Mean Titers (GMT) of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 15	DENV-2	4142.7 titer
TDV: DENV Immune: DENV-3 Positive	Geometric Mean Titers (GMT) of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 15	DENV-3	7244.0 titer
TDV: DENV Immune: DENV-3 Positive	Geometric Mean Titers (GMT) of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 15	DENV-1	5510.0 titer

Primary

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 105

GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.

Time frame: Day 105

Population: PPS included all participants in the FAS who had no major protocol violations. Overall number analyzed are the number of participants with data available for analyses.

Arm	Measure	Group	Value (GEOMETRIC_MEAN)
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 105	DENV-3	221.0 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 105	DENV-1	326.0 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 105	DENV-4	211.6 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 105	DENV-2	3784.9 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 105	DENV-3	2360.0 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 105	DENV-2	5810.0 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 105	DENV-4	2181.0 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 105	DENV-1	13354.0 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 105	DENV-4	4011.8 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 105	DENV-1	6720.6 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 105	DENV-2	5635.6 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 105	DENV-3	12835.4 titer

Primary

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 120 (Month 4)

GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.

Time frame: Day 120 (Month 4)

Population: PPS included all participants in the FAS who had no major protocol violations. Overall number analyzed are the number of participants with data available for analyses.

Arm	Measure	Group	Value (GEOMETRIC_MEAN)
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 120 (Month 4)	DENV-1	433.8 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 120 (Month 4)	DENV-2	3636.1 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 120 (Month 4)	DENV-3	132.1 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 120 (Month 4)	DENV-4	112.3 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 120 (Month 4)	DENV-4	2428.6 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 120 (Month 4)	DENV-1	27123.8 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 120 (Month 4)	DENV-3	4179.0 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 120 (Month 4)	DENV-2	7424.1 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 120 (Month 4)	DENV-4	3835.1 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 120 (Month 4)	DENV-2	6187.5 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 120 (Month 4)	DENV-3	10402.8 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 120 (Month 4)	DENV-1	9242.2 titer

Primary

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 150 (Month 5)

GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.

Time frame: Day 150 (Month 5)

Population: PPS included all participants in the FAS who had no major protocol violations. Overall number analyzed are the number of participants with data available for analyses.

Arm	Measure	Group	Value (GEOMETRIC_MEAN)
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 150 (Month 5)	DENV-1	266.7 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 150 (Month 5)	DENV-2	2415.2 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 150 (Month 5)	DENV-3	137.0 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 150 (Month 5)	DENV-4	120.5 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 150 (Month 5)	DENV-4	1729.0 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 150 (Month 5)	DENV-1	15703.0 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 150 (Month 5)	DENV-3	2829.0 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 150 (Month 5)	DENV-2	7081.0 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 150 (Month 5)	DENV-4	3593.4 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 150 (Month 5)	DENV-2	4589.6 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 150 (Month 5)	DENV-3	8627.9 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 150 (Month 5)	DENV-1	7652.0 titer

Primary

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 180 (Month 6)

GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.

Time frame: Day 180 (Month 6)

Population: PPS included all participants in the FAS who had no major protocol violations. Overall number analyzed are the number of participants with data available for analyses.

Arm	Measure	Group	Value (GEOMETRIC_MEAN)
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 180 (Month 6)	DENV-1	194.4 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 180 (Month 6)	DENV-2	1920.1 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 180 (Month 6)	DENV-3	98.2 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 180 (Month 6)	DENV-4	76.1 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 180 (Month 6)	DENV-4	2797.3 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 180 (Month 6)	DENV-1	22880.8 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 180 (Month 6)	DENV-3	4198.3 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 180 (Month 6)	DENV-2	10697.4 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 180 (Month 6)	DENV-4	2742.4 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 180 (Month 6)	DENV-2	5458.3 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 180 (Month 6)	DENV-3	7495.0 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 180 (Month 6)	DENV-1	4101.6 titer

Primary

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 270 (Month 9)

GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.

Time frame: Day 270 (Month 9)

Population: PPS included all participants in the FAS who had no major protocol violations. Overall number analyzed are the number of participants with data available for analyses.

Arm	Measure	Group	Value (GEOMETRIC_MEAN)
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 270 (Month 9)	DENV-1	121.7 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 270 (Month 9)	DENV-2	1584.0 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 270 (Month 9)	DENV-3	85.6 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 270 (Month 9)	DENV-4	39.5 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 270 (Month 9)	DENV-4	1684.0 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 270 (Month 9)	DENV-1	16158.0 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 270 (Month 9)	DENV-3	3727.0 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 270 (Month 9)	DENV-2	8585.0 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 270 (Month 9)	DENV-4	2021.3 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 270 (Month 9)	DENV-2	3925.6 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 270 (Month 9)	DENV-3	5985.8 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 270 (Month 9)	DENV-1	3913.9 titer

Primary

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 30 (Month 1)

GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.

Time frame: Day 30 (Month 1)

Population: PPS included all participants in the FAS who had no major protocol violations.

Arm	Measure	Group	Value (GEOMETRIC_MEAN)
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 30 (Month 1)	DENV-3	344.7 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 30 (Month 1)	DENV-2	11557.1 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 30 (Month 1)	DENV-1	336.1 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 30 (Month 1)	DENV-4	141.1 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 30 (Month 1)	DENV-4	5094.3 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 30 (Month 1)	DENV-1	45437.3 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 30 (Month 1)	DENV-2	12317.0 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 30 (Month 1)	DENV-3	7273.6 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 30 (Month 1)	DENV-1	11091.9 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 30 (Month 1)	DENV-4	5231.1 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 30 (Month 1)	DENV-3	19062.2 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 30 (Month 1)	DENV-2	12221.9 titer

Primary

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 360 (Month 12)

GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.

Time frame: Day 360 (Month 12)

Population: PPS included all participants in the FAS who had no major protocol violations. Overall number analyzed are the number of participants with data available for analyses.

Arm	Measure	Group	Value (GEOMETRIC_MEAN)
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 360 (Month 12)	DENV-2	1287.8 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 360 (Month 12)	DENV-1	154.6 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 360 (Month 12)	DENV-3	77.0 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 360 (Month 12)	DENV-4	29.8 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 360 (Month 12)	DENV-4	1171.0 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 360 (Month 12)	DENV-3	4112.0 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 360 (Month 12)	DENV-1	17546.0 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 360 (Month 12)	DENV-2	9623.0 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 360 (Month 12)	DENV-1	2623.5 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 360 (Month 12)	DENV-2	1523.7 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 360 (Month 12)	DENV-3	5287.8 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 360 (Month 12)	DENV-4	1695.3 titer

Primary

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 60 (Month 2)

GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.

Time frame: Day 60 (Month 2)

Population: PPS included all participants in the FAS who had no major protocol violations.

Arm	Measure	Group	Value (GEOMETRIC_MEAN)
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 60 (Month 2)	DENV-1	258.5 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 60 (Month 2)	DENV-2	6293.0 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 60 (Month 2)	DENV-3	174.6 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 60 (Month 2)	DENV-4	78.2 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 60 (Month 2)	DENV-4	6122.7 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 60 (Month 2)	DENV-1	28109.0 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 60 (Month 2)	DENV-3	6174.2 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 60 (Month 2)	DENV-2	9641.1 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 60 (Month 2)	DENV-4	4254.8 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 60 (Month 2)	DENV-2	7236.5 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 60 (Month 2)	DENV-3	15536.5 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 60 (Month 2)	DENV-1	7827.8 titer

Primary

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 90 (Month 3)

GMT of neutralizing antibodies were measured for each of the four dengue serotypes: DENV-1, DENV-2, DENV-3, and DENV-4, by MNT50.

Time frame: Day 90 (Month 3)

Population: PPS included all participants in the FAS who had no major protocol violations.

Arm	Measure	Group	Value (GEOMETRIC_MEAN)
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 90 (Month 3)	DENV-4	79.2 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 90 (Month 3)	DENV-3	145.7 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 90 (Month 3)	DENV-2	4077.0 titer
TDV: Flavivirus-naïve	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 90 (Month 3)	DENV-1	197.5 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 90 (Month 3)	DENV-3	7043.3 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 90 (Month 3)	DENV-2	9167.4 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 90 (Month 3)	DENV-1	24989.5 titer
TDV: DENV Immune: DENV-1 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 90 (Month 3)	DENV-4	3240.2 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 90 (Month 3)	DENV-2	5450.5 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 90 (Month 3)	DENV-1	8111.3 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 90 (Month 3)	DENV-4	4372.2 titer
TDV: DENV Immune: DENV-3 Positive	GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 90 (Month 3)	DENV-3	10172.1 titer

Secondary

Duration of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination

The duration of vaccine viremia for each vaccine strain was defined as the date when vaccine viremia was last detected (positive result) to date when vaccine viremia was first detected (positive result) + 1 day. It was assessed for each of the four vaccine strains: TDV-1, TDV-2, TDV-3 and TDV-4. Vaccine viral RNA was detected by qRT-PCR assay. Safety Analysis Set included all participants who received at least 1 dose of trial vaccine.

Time frame: Up to Day 120 (Month 4)

Population: Safety Analysis Set included all participants who received at least one dose of trial vaccine. One participant was seropositive for all dengue strains at Screening and was therefore not allocated to dengue serotype 1 or 3 positive groups. The participant did receive two vaccine doses and was thus included in Safety Analysis Set. Overall number analyzed=participants with data available for analyses. Number analyzed= participants with data available for analysis for the specified category.

Arm	Measure	Group	Value (MEDIAN)
TDV: Flavivirus-naïve	Duration of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	TDV-2	4.0 days
TDV: Flavivirus-naïve	Duration of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	TDV-4	3.0 days
TDV: DENV Immune: DENV-1 Positive	Duration of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	TDV-2	1.0 days
TDV: DENV Immune: DENV-1 Positive	Duration of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	TDV-4	1.0 days
TDV: DENV Immune: DENV-3 Positive	Duration of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	TDV-2	2.5 days
TDV: DENV Immune: DENV-3 Positive	Duration of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	TDV-4	1.0 days

Secondary

Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination

Vaccine viremia was assessed for each of the four vaccine strain serotypes: TDV-1, TDV-2, TDV-3 and TDV-4. Vaccine viral RNA was detected by qRT-PCR assay.

Time frame: Days 6, 9, 12, and 15

Arm	Measure	Group	Value (MEAN)	Dispersion
TDV: Flavivirus-naïve	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-4	3.80 log10 of genome equivalent per mL	—
TDV: Flavivirus-naïve	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-2	3.43 log10 of genome equivalent per mL	Standard Deviation 0.14
TDV: Flavivirus-naïve	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-4	3.98 log10 of genome equivalent per mL	—
TDV: Flavivirus-naïve	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-2	3.46 log10 of genome equivalent per mL	Standard Deviation 0.485
TDV: Flavivirus-naïve	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-2	3.32 log10 of genome equivalent per mL	Standard Deviation 0.172
TDV: DENV Immune: DENV-1 Positive	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-2	3.65 log10 of genome equivalent per mL	—
TDV: DENV Immune: DENV-1 Positive	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-2	3.94 log10 of genome equivalent per mL	Standard Deviation 0.568
TDV: DENV Immune: DENV-1 Positive	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-4	3.90 log10 of genome equivalent per mL	—
TDV: DENV Immune: DENV-3 Positive	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-4	3.71 log10 of genome equivalent per mL	—
TDV: DENV Immune: DENV-3 Positive	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-2	4.06 log10 of genome equivalent per mL	Standard Deviation 1.003
TDV: DENV Immune: DENV-3 Positive	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-2	3.17 log10 of genome equivalent per mL	—
Unknown	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-1	— log10 of genome equivalent per mL	—
Unknown	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-3	— log10 of genome equivalent per mL	—
Unknown	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-1	— log10 of genome equivalent per mL	—
Unknown	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-4	— log10 of genome equivalent per mL	—
Unknown	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-3	— log10 of genome equivalent per mL	—
Unknown	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-3	— log10 of genome equivalent per mL	—
Unknown	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-3	— log10 of genome equivalent per mL	—
Unknown	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-1	— log10 of genome equivalent per mL	—
Unknown	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-4	— log10 of genome equivalent per mL	—
Unknown	Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-1	— log10 of genome equivalent per mL	—

Secondary

Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV

The magnitude of cellular immune response was assessed by the number of SFC/10\^6 PBMCs. IFN-γ ELISpot response \>3 times higher compared with baseline (no peptide) and ≥5 spots per 10\^6 PBMCs was defined as cellular immune response. Cellular immune response to any peptide pool was reported. The peptide pools included prME, C, NS1, NS2, NS3, NS4 and NS5 for DENV-1, DENV-2, DENV-3 and DENV-4.

Time frame: Days 30 (Month 1), 90 (Month 3), 120 (Month 4), 180 (Month 6), 360 (Month 12)

Population: PPS included all participants in the FAS who had no major protocol violations. Number analyzed is the number of participants with data available for analysis for the specified timepoint.

Arm	Measure	Group	Value (MEAN)	Dispersion
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-3 Day 360 (Month 12)	137.6666 SFC/10^6 PBMCs	Standard Deviation 194.74138
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-2 Day 120 (Month 4)	999.3056 SFC/10^6 PBMCs	Standard Deviation 1416.74554
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-4 Day 360 (Month 12)	215.0000 SFC/10^6 PBMCs	Standard Deviation 325.02308
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-3 Day 180 (Month 6)	164.0909 SFC/10^6 PBMCs	Standard Deviation 233.54441
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-2 Day 180 (Month 6)	965.1111 SFC/10^6 PBMCs	Standard Deviation 1154.31464
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-1 Day 360 (Month 12)	235.1667 SFC/10^6 PBMCs	Standard Deviation 340.48572
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-3 Day 120 (Month 4)	156.1112 SFC/10^6 PBMCs	Standard Deviation 280.56878
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-2 Day 360 (Month 12)	974.0909 SFC/10^6 PBMCs	Standard Deviation 1266.49305
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-1 Day 180 (Month 6)	162.5000 SFC/10^6 PBMCs	Standard Deviation 237.01829
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-3 Day 90 (Month 3)	184.8148 SFC/10^6 PBMCs	Standard Deviation 273.48687
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-3 Day 30 (Month 1)	246.5789 SFC/10^6 PBMCs	Standard Deviation 331.14209
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-1 Day 90 (Month 3)	189.5834 SFC/10^6 PBMCs	Standard Deviation 350.89563
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-4 Day 120 (Month 4)	172.6388 SFC/10^6 PBMCs	Standard Deviation 373.16791
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-1 Day 30 (Month 1)	232.3016 SFC/10^6 PBMCs	Standard Deviation 407.5545
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-4 Day 90 (Month 3)	153.0392 SFC/10^6 PBMCs	Standard Deviation 290.81317
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-2 Day 30 (Month 1)	1156.9048 SFC/10^6 PBMCs	Standard Deviation 1676.59869
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-4 Day 180 (Month 6)	162.2619 SFC/10^6 PBMCs	Standard Deviation 378.98856
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-4 Day 30 (Month 1)	224.0625 SFC/10^6 PBMCs	Standard Deviation 420.90109
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-2 Day 90 (Month 3)	912.4603 SFC/10^6 PBMCs	Standard Deviation 979.8106
TDV: Flavivirus-naïve	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-1 Day 120 (Month 4)	209.8611 SFC/10^6 PBMCs	Standard Deviation 329.52941
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-4 Day 120 (Month 4)	57.5000 SFC/10^6 PBMCs	Standard Deviation 74.24621
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-1 Day 30 (Month 1)	2480.0000 SFC/10^6 PBMCs	Standard Deviation 3486.03643
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-1 Day 90 (Month 3)	1772.5000 SFC/10^6 PBMCs	Standard Deviation 2485.48034
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-1 Day 120 (Month 4)	1517.5000 SFC/10^6 PBMCs	Standard Deviation 2138.99801
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-1 Day 180 (Month 6)	1994.1665 SFC/10^6 PBMCs	Standard Deviation 2806.03517
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-1 Day 360 (Month 12)	5.0000 SFC/10^6 PBMCs	—
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-2 Day 30 (Month 1)	1847.5000 SFC/10^6 PBMCs	Standard Deviation 2365.27218
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-2 Day 90 (Month 3)	1462.5000 SFC/10^6 PBMCs	Standard Deviation 1750.08928
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-2 Day 120 (Month 4)	1237.5000 SFC/10^6 PBMCs	Standard Deviation 1566.24152
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-2 Day 180 (Month 6)	2070.0000 SFC/10^6 PBMCs	Standard Deviation 2807.21392
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-2 Day 360 (Month 12)	180.0000 SFC/10^6 PBMCs	—
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-3 Day 30 (Month 1)	2035.0000 SFC/10^6 PBMCs	Standard Deviation 2807.21392
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-3 Day 90 (Month 3)	215.0000 SFC/10^6 PBMCs	Standard Deviation 282.84271
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-3 Day 120 (Month 4)	1565.0000 SFC/10^6 PBMCs	Standard Deviation 2192.03102
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-3 Day 180 (Month 6)	1726.6665 SFC/10^6 PBMCs	Standard Deviation 2413.59091
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-3 Day 360 (Month 12)	5.0000 SFC/10^6 PBMCs	—
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-4 Day 30 (Month 1)	395.0000 SFC/10^6 PBMCs	Standard Deviation 473.76154
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-4 Day 90 (Month 3)	362.5000 SFC/10^6 PBMCs	Standard Deviation 477.29708
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-4 Day 180 (Month 6)	573.3330 SFC/10^6 PBMCs	—
TDV: DENV Immune: DENV-1 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-4 Day 360 (Month 12)	40.0000 SFC/10^6 PBMCs	—
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-1 Day 90 (Month 3)	235.0000 SFC/10^6 PBMCs	Standard Deviation 109.65856
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-3 Day 180 (Month 6)	120.5553 SFC/10^6 PBMCs	Standard Deviation 132.31197
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-2 Day 90 (Month 3)	352.2223 SFC/10^6 PBMCs	Standard Deviation 267.42243
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-4 Day 360 (Month 12)	75.8335 SFC/10^6 PBMCs	Standard Deviation 62.46086
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-3 Day 360 (Month 12)	123.3335 SFC/10^6 PBMCs	Standard Deviation 16.49892
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-2 Day 30 (Month 1)	551.6667 SFC/10^6 PBMCs	Standard Deviation 309.89245
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-4 Day 180 (Month 6)	155.0000 SFC/10^6 PBMCs	Standard Deviation 165.86485
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-4 Day 30 (Month 1)	153.3333 SFC/10^6 PBMCs	Standard Deviation 219.10804
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-1 Day 360 (Month 12)	104.1665 SFC/10^6 PBMCs	Standard Deviation 69.53193
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-1 Day 30 (Month 1)	301.6667 SFC/10^6 PBMCs	Standard Deviation 159.39992
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-4 Day 90 (Month 3)	71.6667 SFC/10^6 PBMCs	Standard Deviation 38.11558
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-1 Day 180 (Month 6)	242.7777 SFC/10^6 PBMCs	Standard Deviation 166.35251
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-3 Day 30 (Month 1)	295.0000 SFC/10^6 PBMCs	Standard Deviation 115.32563
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-2 Day 360 (Month 12)	149.1665 SFC/10^6 PBMCs	Standard Deviation 93.10263
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-1 Day 120 (Month 4)	116.6667 SFC/10^6 PBMCs	Standard Deviation 76.53975
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-3 Day 90 (Month 3)	226.1113 SFC/10^6 PBMCs	Standard Deviation 212.99673
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-2 Day 180 (Month 6)	375.5557 SFC/10^6 PBMCs	Standard Deviation 70.56015
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-4 Day 120 (Month 4)	160.0000 SFC/10^6 PBMCs	Standard Deviation 205.36553
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-3 Day 120 (Month 4)	353.3333 SFC/10^6 PBMCs	Standard Deviation 158.61379
TDV: DENV Immune: DENV-3 Positive	Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV	DENV-2 Day 120 (Month 4)	161.6667 SFC/10^6 PBMCs	Standard Deviation 150.52685

Secondary

Percentage of Participants With at Least One Unsolicited Adverse Events (AEs) Following Each Vaccination

An AE is defined as any untoward medical occurrence in a clinical investigation participant administered a study vaccine; it does not necessarily have to have a causal relationship with study vaccine administration.

Time frame: Up to 28 days (day of vaccination + 27 days) after administration of each vaccine dose given on Day 1 (Month 0) and 90 (Month 3)

Population: Safety Analysis Set included all participants who received at least one dose of trial vaccine. One participant was seropositive for all dengue strains at Screening and was therefore not allocated to dengue serotype 1 or 3 positive groups. The participant did receive two vaccine doses and was thus included in Safety Analysis Set. Number analyzed is the number of participants with data available for analysis for the specified category.

Arm	Measure	Group	Value (NUMBER)
TDV: Flavivirus-naïve	Percentage of Participants With at Least One Unsolicited Adverse Events (AEs) Following Each Vaccination	After Second Vaccination	36.4 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With at Least One Unsolicited Adverse Events (AEs) Following Each Vaccination	After First Vaccination	63.6 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With at Least One Unsolicited Adverse Events (AEs) Following Each Vaccination	After First Vaccination	75.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With at Least One Unsolicited Adverse Events (AEs) Following Each Vaccination	After Second Vaccination	0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With at Least One Unsolicited Adverse Events (AEs) Following Each Vaccination	After First Vaccination	66.7 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With at Least One Unsolicited Adverse Events (AEs) Following Each Vaccination	After Second Vaccination	100.0 percentage of participants
Unassigned Group	Percentage of Participants With at Least One Unsolicited Adverse Events (AEs) Following Each Vaccination	After Second Vaccination	0 percentage of participants
Unassigned Group	Percentage of Participants With at Least One Unsolicited Adverse Events (AEs) Following Each Vaccination	After First Vaccination	0 percentage of participants

Secondary

Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)

IFN-γ ELISpot response \>3 times higher compared with baseline (no peptide) and ≥5 spots per 10\^6 peripheral blood mononuclear cells (PBMCs) was defined as cellular immune response. Cellular immune response to any peptide pool was reported. The peptide pools included pre-membrane envelope (prME), capsid (C), non-structural proteins (NS): NS1, NS2, NS3, NS4 and NS5 for DENV-1, DENV-2, DENV-3 and DENV-4.

Time frame: Days 30 (Month 1), 90 (Month 3), 120 (Month 4), 180 (Month 6), 360 (Month 12)

Population: PPS included all participants in the FAS who had no major protocol violations. Number analyzed is the number of participants with data available for analysis for the specified timepoint.

Arm	Measure	Group	Value (NUMBER)
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-1 Day 120 (Month 4)	100 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-3 Day 180 (Month 6)	73.3 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-2 Day 120 (Month 4)	100 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-4 Day 360 (Month 12)	54.5 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-3 Day 120 (Month 4)	100 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-2 Day 180 (Month 6)	100 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-4 Day 120 (Month 4)	100 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-3 Day 90 (Month 3)	85.7 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-2 Day 360 (Month 12)	100 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-1 Day 180 (Month 6)	93.3 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-3 Day 30 (Month 1)	90.5 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-1 Day 90 (Month 3)	95.2 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-4 Day 90 (Month 3)	81.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-1 Day 360 (Month 12)	90.9 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-1 Day 30 (Month 1)	100 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-4 Day 30 (Month 1)	76.2 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-2 Day 30 (Month 1)	100 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-4 Day 180 (Month 6)	93.3 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-3 Day 360 (Month 12)	90.9 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-2 Day 90 (Month 3)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-1 Day 360 (Month 12)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-1 Day 30 (Month 1)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-1 Day 90 (Month 3)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-1 Day 120 (Month 4)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-1 Day 180 (Month 6)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-4 Day 360 (Month 12)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-2 Day 30 (Month 1)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-2 Day 90 (Month 3)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-2 Day 120 (Month 4)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-2 Day 180 (Month 6)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-2 Day 360 (Month 12)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-3 Day 30 (Month 1)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-3 Day 90 (Month 3)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-3 Day 120 (Month 4)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-3 Day 180 (Month 6)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-3 Day 360 (Month 12)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-4 Day 30 (Month 1)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-4 Day 90 (Month 3)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-4 Day 120 (Month 4)	100 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-4 Day 180 (Month 6)	50.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-2 Day 90 (Month 3)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-4 Day 120 (Month 4)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-3 Day 180 (Month 6)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-2 Day 30 (Month 1)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-1 Day 90 (Month 3)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-3 Day 360 (Month 12)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-1 Day 360 (Month 12)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-4 Day 360 (Month 12)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-4 Day 30 (Month 1)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-1 Day 180 (Month 6)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-4 Day 180 (Month 6)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-2 Day 360 (Month 12)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-4 Day 90 (Month 3)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-3 Day 30 (Month 1)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-2 Day 180 (Month 6)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-1 Day 120 (Month 4)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-3 Day 90 (Month 3)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-2 Day 120 (Month 4)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-1 Day 30 (Month 1)	100 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)	DENV-3 Day 120 (Month 4)	100 percentage of participants

Secondary

Percentage of Participants With Medically Attended AEs (MAAEs)

MAAEs was defined as AEs leading to a medical visit to or by a healthcare professional, including visits to an emergency department, but not fulfilling seriousness criteria.

Time frame: From first vaccination (Day 1) through end of study (Day 360 [Month 12])

Arm	Measure	Value (NUMBER)
TDV: Flavivirus-naïve	Percentage of Participants With Medically Attended AEs (MAAEs)	45.5 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Medically Attended AEs (MAAEs)	50.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Medically Attended AEs (MAAEs)	33.3 percentage of participants
Unassigned Group	Percentage of Participants With Medically Attended AEs (MAAEs)	0 percentage of participants

Secondary

Percentage of Participants With Serious Adverse Events (SAEs)

A SAE is defined as any untoward medical occurrence or effect that at any dose results in death, is life-threatening, requires inpatient hospitalization or prolongation of existing hospitalization, results in persistent or / significant disability / incapacity, is a congenital anomaly / birth defect or is medically important due to other reasons than the aforementioned criteria.

Time frame: From first vaccination (Day 1) through end of study (Day 360 [Month 12])

Arm	Measure	Value (NUMBER)
TDV: Flavivirus-naïve	Percentage of Participants With Serious Adverse Events (SAEs)	4.5 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Serious Adverse Events (SAEs)	25.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Serious Adverse Events (SAEs)	0 percentage of participants
Unassigned Group	Percentage of Participants With Serious Adverse Events (SAEs)	0 percentage of participants

Secondary

Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination

Solicited local AEs (at injection site) were collected by participants using diary cards within 7 days after vaccination and included injection site pain \[Grade 0 (no pain), 1 (mild: no interference with daily activity), 2 (moderate: interference with daily activity with or without treatment) and 3 (severe: prevents daily activity with or without treatment)\], injection site erythema \[Grade 0 (\<25 mm), 1 (25 - ≤ 50 mm), 2 (\>50 - ≤ 100 mm), 3 (\> 100 mm)\] and injection site swelling \[Grade 0 (\<25 mm), 1 (25 - ≤ 50 mm), 2 (\>50 - ≤ 100 mm), 3 (\> 100 mm)\]. Only categories for which there was at least 1 participant are reported.

Time frame: Within 7 days after each of the vaccine dose given on Day 1 (Month 0) and 90 (Month 3)

Population: Safety Analysis Set included all participants who received at least one dose of trial vaccine. One participant was seropositive for all dengue strains at Screening and was therefore not allocated to dengue serotype 1 or 3 positive groups. The participant did receive two vaccine doses and was thus included in Safety Analysis Set. Number analyzed is the number of participants with data available for analysis for the specified category.

Arm	Measure	Group	Value (NUMBER)
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After Second Vaccination: Pain	59.1 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After First Vaccination: Erythema	40.9 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After First Vaccination: Any Solicited Local AEs	54.5 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After First Vaccination: Pain	40.9 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After Second Vaccination: Any Solicited Local AEs	68.2 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After Second Vaccination: Erythema	31.8 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After Second Vaccination: Swelling	9.1 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After Second Vaccination: Any Solicited Local AEs	50.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After First Vaccination: Pain	25.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After Second Vaccination: Erythema	0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After First Vaccination: Any Solicited Local AEs	25.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After Second Vaccination: Pain	50.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After Second Vaccination: Swelling	0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After First Vaccination: Erythema	0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After Second Vaccination: Swelling	0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After First Vaccination: Erythema	33.3 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After Second Vaccination: Pain	66.7 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After Second Vaccination: Erythema	33.3 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After First Vaccination: Any Solicited Local AEs	66.7 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After First Vaccination: Pain	66.7 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After Second Vaccination: Any Solicited Local AEs	66.7 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After Second Vaccination: Swelling	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After First Vaccination: Erythema	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After Second Vaccination: Any Solicited Local AEs	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After First Vaccination: Any Solicited Local AEs	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After Second Vaccination: Erythema	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After Second Vaccination: Pain	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination	After First Vaccination: Pain	0 percentage of participants

Secondary

Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination

Solicited systemic AEs were collected by participants using diary cards within 14 days after vaccination and will include fever, headache, asthenia, malaise and myalgia. Severity grades are: Grade 0: none, Grade 1: mild (no interference with daily activity), Grade 2: moderate (interference with daily activity with or without treatment), Grade 3: severe (prevents normal daily activity with or without treatment). A systemic AE of fever (defined as body temperature ≥ 100.4°F regardless of method taken) was derived from a daily temperature reading recorded within 14 days after vaccination. Only categories for which there was at least 1 participant are reported.

Time frame: Within 14 days after each of the vaccine dose given on Day 1 (Month 0) and 90 (Month 3)

Population: Safety Analysis Set included all participants who received at least one dose of trial vaccine. One participant was seropositive for all dengue strains at Screening and was therefore not allocated to dengue serotype 1 or 3 positive groups. The participant did receive two vaccine doses and was thus included in Safety Analysis Set. Number analyzed is the number of participants with data available for analysis for the specified category.

Arm	Measure	Group	Value (NUMBER)
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Any Solicited Systemic AE	27.3 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Asthenia	18.2 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Asthenia	31.8 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Headache	50.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Myalgia	40.9 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Any Solicited Systemic AE	68.2 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Myalgia	9.1 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Headache	13.6 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Fever	4.5 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Malaise	13.6 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Malaise	54.5 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Myalgia	25.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Any Solicited Systemic AE	75.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Fever	0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Myalgia	0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Headache	50.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Asthenia	25.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Malaise	25.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Any Solicited Systemic AE	0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Headache	0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Asthenia	0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Malaise	0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Malaise	100.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Myalgia	100.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Headache	33.3 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Any Solicited Systemic AE	66.7 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Headache	66.7 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Any Solicited Systemic AE	100.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Malaise	66.7 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Myalgia	0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Asthenia	0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Asthenia	66.7 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Fever	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Asthenia	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Asthenia	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Malaise	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Fever	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Any Solicited Systemic AE	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Myalgia	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Malaise	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Headache	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After Second Vaccination: Myalgia	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Headache	0 percentage of participants
Unassigned Group	Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination	After First Vaccination: Any Solicited Systemic AE	0 percentage of participants

Secondary

Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination

Vaccine viremia was assessed for each of the four vaccine strain serotypes: TDV-1, TDV-2, TDV-3 and TDV-4. Vaccine viral ribonucleic acid (RNA) was detected by a quantitative reverse transcription-polymerase chain reaction (qRT-PCR) assay. Percentages were rounded off to the nearest decimal place.

Time frame: Days 6, 9, 12, 15, 30 (Month 1), 90 (Month 3), 96, 99, 102, 105, 120 (Month 4)

Population: Safety Analysis Set included all participants who received at least one dose of trial vaccine. One participant was seropositive for all dengue strains at Screening and was therefore not allocated to dengue serotype 1 or 3 positive groups. The participant did receive two vaccine doses and was thus included in Safety Analysis Set. Number analyzed is the number of participants with data available for analysis for the specified category.

Arm	Measure	Group	Value (NUMBER)
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-4	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-1	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 102: TDV-1	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-3	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 96: TDV-1	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 120 (Month 4): TDV-4	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-1	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-2	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 99: TDV-3	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-3	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-3	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-2	36.4 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 105: TDV-1	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-2	50.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-2	19.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-3	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 99: TDV-2	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-1	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 90 (Month 3): TDV-2	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-4	4.8 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-4	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-4	4.5 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 105: TDV-2	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 96: TDV-2	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 90 (Month 3): TDV-3	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 90 (Month 3): TDV-1	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 105: TDV-3	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 99: TDV-1	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 30 (Month 1): TDV-4	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 102: TDV-2	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 105: TDV-4	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 96: TDV-4	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 120 (Month 4): TDV-1	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 102: TDV-3	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 30 (Month 1): TDV-2	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 99: TDV-4	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 120 (Month 4): TDV-2	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 102: TDV-4	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 120 (Month 4): TDV-3	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 96: TDV-3	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 30 (Month 1): TDV-1	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 90 (Month 3): TDV-4	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 30 (Month 1): TDV-3	0.0 percentage of participants
TDV: Flavivirus-naïve	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 99: TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 102: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 96: TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 102: TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 102: TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 99: TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 105: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 105: TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 105: TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 105: TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 120 (Month 4): TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 102: TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 120 (Month 4): TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 120 (Month 4): TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 120 (Month 4): TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-2	75.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-4	25.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-2	25.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 30 (Month 1): TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 30 (Month 1): TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 30 (Month 1): TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 30 (Month 1): TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 90 (Month 3): TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 90 (Month 3): TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 90 (Month 3): TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 96: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 96: TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 90 (Month 3): TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 96: TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 99: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-1 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 99: TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 105: TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 102: TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 120 (Month 4): TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 120 (Month 4): TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 96: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 30 (Month 1): TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 96: TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 120 (Month 4): TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 102: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 30 (Month 1): TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 105: TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 96: TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 30 (Month 1): TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 90 (Month 3): TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 99: TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 90 (Month 3): TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 102: TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 105: TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 99: TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-4	33.3 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 90 (Month 3): TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 99: TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-2	66.7 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 90 (Month 3): TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-2	33.3 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 105: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-3	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 102: TDV-4	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 99: TDV-1	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 30 (Month 1): TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 120 (Month 4): TDV-2	0.0 percentage of participants
TDV: DENV Immune: DENV-3 Positive	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 96: TDV-2	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 120 (Month 4): TDV-4	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-3	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-4	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-1	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 30 (Month 1): TDV-2	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 30 (Month 1): TDV-3	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 90 (Month 3): TDV-1	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 96: TDV-1	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 96: TDV-4	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 99: TDV-4	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 105: TDV-4	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 120 (Month 4): TDV-3	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-1	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 6: TDV-2	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-2	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-3	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 9: TDV-4	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-1	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-2	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-3	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 12: TDV-4	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-1	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-2	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-3	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 15: TDV-4	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 30 (Month 1): TDV-1	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 30 (Month 1): TDV-4	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 90 (Month 3): TDV-2	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 90 (Month 3): TDV-3	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 90 (Month 3): TDV-4	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 96: TDV-2	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 96: TDV-3	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 99: TDV-1	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 99: TDV-2	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 99: TDV-3	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 102: TDV-1	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 102: TDV-2	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 102: TDV-3	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 102: TDV-4	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 105: TDV-1	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 105: TDV-2	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 105: TDV-3	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 120 (Month 4): TDV-1	0.0 percentage of participants
Unassigned Group	Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination	Day 120 (Month 4): TDV-2	0.0 percentage of participants

Secondary

Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)

Phenotype characterization of cellular immune response was performed in a subset of participants with IFN- γ ELISPOT responses \>50 SFC/10\^6 cells and availability of sufficient cells. Markers included cluster of differentiation (CD) 4, CD8, IFN-γ, tumor necrosis factor-alpha (TNF-α) and interleukin-2 (IL-2). The peptide pools included C, NS1, NS2/4, NS3, NS5 for DENV-2 and prME for DENV-1, DENV-2, DENV-3 and DENV-4.

Time frame: Days 15, 30 (Month 1), 90 (Month 3), 105, 120 (Month 4), and 360 (Month 12)

Population: Intracellular Cytokine Staining (ICS) Subset included participants from PPS (all participants in the FAS who had no major protocol violations) who had IFN-γ ELISPOT responses \> 50 SFC/10\^6 PBMCs and availability of sufficient cells for analysis. Number analyzed is the number of participants with data available for analysis for the specified timepoint.

Arm	Measure	Group	Value (MEAN)	Dispersion
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 15	0.0039528 percentage of CD4+ T cells	Standard Deviation 0.00428498
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0466667 percentage of CD4+ T cells	Standard Deviation 0.05889822
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0028144 percentage of CD4+ T cells	Standard Deviation 0.00395317
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.0043484 percentage of CD4+ T cells	Standard Deviation 0.00418555
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0089474 percentage of CD4+ T cells	Standard Deviation 0.01355021
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0040230 percentage of CD4+ T cells	Standard Deviation 0.00533216
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.0019436 percentage of CD4+ T cells	Standard Deviation 0.0023377
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 105	0.0024900 percentage of CD4+ T cells	Standard Deviation 0.00217522
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 105	0.0034460 percentage of CD4+ T cells	Standard Deviation 0.00473493
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 105	0.0012450 percentage of CD4+ T cells	Standard Deviation 0.00195501
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 15	0.0020952 percentage of CD4+ T cells	Standard Deviation 0.00545807
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0004250 percentage of CD4+ T cells	Standard Deviation 0.00128026
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.0014041 percentage of CD4+ T cells	Standard Deviation 0.00169202
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 15	0.0015836 percentage of CD4+ T cells	Standard Deviation 0.00205944
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0027084 percentage of CD4+ T cells	Standard Deviation 0.00347026
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0009221 percentage of CD4+ T cells	Standard Deviation 0.00118263
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0033810 percentage of CD4+ T cells	Standard Deviation 0.00696043
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 15	0.0023484 percentage of CD4+ T cells	Standard Deviation 0.00373999
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 15	0.0063457 percentage of CD4+ T cells	Standard Deviation 0.0073928
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0015714 percentage of CD4+ T cells	Standard Deviation 0.00413003
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0057482 percentage of CD4+ T cells	Standard Deviation 0.01145463
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0136346 percentage of CD4+ T cells	Standard Deviation 0.01827227
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0018916 percentage of CD4+ T cells	Standard Deviation 0.0029147
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0054000 percentage of CD4+ T cells	Standard Deviation 0.00546757
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0102555 percentage of CD4+ T cells	Standard Deviation 0.00890732
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 15	0.0007143 percentage of CD4+ T cells	Standard Deviation 0.00327327
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 105	0.0032733 percentage of CD4+ T cells	Standard Deviation 0.00561714
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 105	0.0086980 percentage of CD4+ T cells	Standard Deviation 0.00422567
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0060967 percentage of CD4+ T cells	Standard Deviation 0.01538351
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0022710 percentage of CD4+ T cells	Standard Deviation 0.00378206
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0096186 percentage of CD4+ T cells	Standard Deviation 0.00919641
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0043409 percentage of CD4+ T cells	Standard Deviation 0.00775431
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 15	0.0024433 percentage of CD4+ T cells	Standard Deviation 0.00478745
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0051619 percentage of CD4+ T cells	Standard Deviation 0.00721208
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0035556 percentage of CD4+ T cells	Standard Deviation 0.00538774
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 105	0.0019320 percentage of CD4+ T cells	Standard Deviation 0.00391432
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 15	0.0012506 percentage of CD4+ T cells	Standard Deviation 0.00145149
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 105	0.0031633 percentage of CD4+ T cells	Standard Deviation 0.00681587
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0014555 percentage of CD4+ T cells	Standard Deviation 0.00277488
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0041405 percentage of CD4+ T cells	Standard Deviation 0.00370046
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 15	0.0042128 percentage of CD4+ T cells	Standard Deviation 0.00495148
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0044725 percentage of CD4+ T cells	Standard Deviation 0.00358891
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0023277 percentage of CD4+ T cells	Standard Deviation 0.00290426
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0063636 percentage of CD4+ T cells	Standard Deviation 0.00569689
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 15	0.0019264 percentage of CD4+ T cells	Standard Deviation 0.00178363
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 105	0.0025060 percentage of CD4+ T cells	Standard Deviation 0.00269757
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 105	0.0048000 percentage of CD4+ T cells	Standard Deviation 0.00672309
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0032638 percentage of CD4+ T cells	Standard Deviation 0.00481301
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0019454 percentage of CD4+ T cells	Standard Deviation 0.00182333
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0322727 percentage of CD4+ T cells	Standard Deviation 0.05355388
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0060286 percentage of CD4+ T cells	Standard Deviation 0.00431794
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0007733 percentage of CD4+ T cells	Standard Deviation 0.00127164
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0052105 percentage of CD4+ T cells	Standard Deviation 0.00611536
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 105	0.0086560 percentage of CD4+ T cells	Standard Deviation 0.0107563
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 15	0.0060766 percentage of CD4+ T cells	Standard Deviation 0.00449815
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0100520 percentage of CD4+ T cells	Standard Deviation 0.00984572
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0074104 percentage of CD4+ T cells	Standard Deviation 0.00838499
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0037728 percentage of CD4+ T cells	Standard Deviation 0.00410557
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0488889 percentage of CD4+ T cells	Standard Deviation 0.08153595
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0079714 percentage of CD4+ T cells	Standard Deviation 0.00798185
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0015660 percentage of CD4+ T cells	Standard Deviation 0.00222761
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 15	0.0018571 percentage of CD4+ T cells	Standard Deviation 0.00381164
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 15	0.0066937 percentage of CD4+ T cells	Standard Deviation 0.007221
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 105	0.0043250 percentage of CD4+ T cells	Standard Deviation 0.00738836
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0013431 percentage of CD4+ T cells	Standard Deviation 0.0015775
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0006924 percentage of CD4+ T cells	Standard Deviation 0.00099937
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0046358 percentage of CD4+ T cells	Standard Deviation 0.00481391
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 105	0.0031633 percentage of CD4+ T cells	Standard Deviation 0.00567028
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.0015674 percentage of CD4+ T cells	Standard Deviation 0.00117213
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0039912 percentage of CD4+ T cells	Standard Deviation 0.0042693
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0063333 percentage of CD4+ T cells	Standard Deviation 0.00867948
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 105	0.0006333 percentage of CD4+ T cells	Standard Deviation 0.00098508
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 105	0.0026620 percentage of CD4+ T cells	Standard Deviation 0.00525083
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 105	0.0057280 percentage of CD4+ T cells	Standard Deviation 0.00796431
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.0022088 percentage of CD4+ T cells	Standard Deviation 0.00270445
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0005960 percentage of CD4+ T cells	Standard Deviation 0.00082714
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0388750 percentage of CD4+ T cells	Standard Deviation 0.04258584
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 15	0.0024265 percentage of CD4+ T cells	Standard Deviation 0.00372846
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 105	0.0031033 percentage of CD4+ T cells	Standard Deviation 0.00107483
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0138750 percentage of CD4+ T cells	Standard Deviation 0.0116795
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0028733 percentage of CD4+ T cells	Standard Deviation 0.00244337
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 15	0.0109444 percentage of CD4+ T cells	Standard Deviation 0.02263644
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0065866 percentage of CD4+ T cells	Standard Deviation 0.00631099
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 105	0.0114020 percentage of CD4+ T cells	Standard Deviation 0.01790945
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0013470 percentage of CD4+ T cells	Standard Deviation 0.00190419
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0037000 percentage of CD4+ T cells	Standard Deviation 0.00877856
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0054914 percentage of CD4+ T cells	Standard Deviation 0.0058113
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 105	0.0014450 percentage of CD4+ T cells	Standard Deviation 0.00172311
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 105	0.0106000 percentage of CD4+ T cells	Standard Deviation 0.01436315
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0079454 percentage of CD4+ T cells	Standard Deviation 0.00902785
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0081765 percentage of CD4+ T cells	Standard Deviation 0.01052518
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 105	0.1933960 percentage of CD4+ T cells	Standard Deviation 0.34758253
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 15	0.0048771 percentage of CD4+ T cells	Standard Deviation 0.00581334
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 15	0.0064286 percentage of CD4+ T cells	Standard Deviation 0.01567345
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 105	0.0049960 percentage of CD4+ T cells	Standard Deviation 0.0111714
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 15	0.0027368 percentage of CD4+ T cells	Standard Deviation 0.00646222
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0040909 percentage of CD4+ T cells	Standard Deviation 0.00870005
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0103333 percentage of CD4+ T cells	Standard Deviation 0.01298075
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0115556 percentage of CD4+ T cells	Standard Deviation 0.01326755
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0105906 percentage of CD4+ T cells	Standard Deviation 0.01290502
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0037701 percentage of CD4+ T cells	Standard Deviation 0.00361243
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0070000 percentage of CD4+ T cells	Standard Deviation 0.01205291
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 15	0.0033889 percentage of CD4+ T cells	Standard Deviation 0.00726101
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0019732 percentage of CD4+ T cells	Standard Deviation 0.00203413
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0047273 percentage of CD4+ T cells	Standard Deviation 0.00864975
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0063636 percentage of CD4+ T cells	Standard Deviation 0.00868646
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 105	0.0010780 percentage of CD4+ T cells	Standard Deviation 0.00144028
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 15	0.0007143 percentage of CD4+ T cells	Standard Deviation 0.00327327
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.0040000 percentage of CD4+ T cells	Standard Deviation 0.00645262
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0029255 percentage of CD4+ T cells	Standard Deviation 0.00304491
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0028357 percentage of CD4+ T cells	Standard Deviation 0.00490865
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 105	0.0020000 percentage of CD4+ T cells	Standard Deviation 0.004
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0024944 percentage of CD4+ T cells	Standard Deviation 0.00265027
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0116332 percentage of CD4+ T cells	Standard Deviation 0.023959
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.0040476 percentage of CD4+ T cells	Standard Deviation 0.00569628
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 15	0.0020067 percentage of CD4+ T cells	Standard Deviation 0.00349245
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.0050019 percentage of CD4+ T cells	Standard Deviation 0.00532053
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 15	0.0045624 percentage of CD4+ T cells	Standard Deviation 0.00373863
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 15	0.0029248 percentage of CD4+ T cells	Standard Deviation 0.00608645
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0058182 percentage of CD4+ T cells	Standard Deviation 0.00726386
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.0079167 percentage of CD4+ T cells	Standard Deviation 0.00674818
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0040266 percentage of CD4+ T cells	Standard Deviation 0.00433388
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 105	0.0021667 percentage of CD4+ T cells	Standard Deviation 0.00325064
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0025411 percentage of CD4+ T cells	Standard Deviation 0.00555028
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 15	0.0007143 percentage of CD4+ T cells	Standard Deviation 0.00197846
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 105	0.0040000 percentage of CD4+ T cells	Standard Deviation 0.00616441
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.0054286 percentage of CD4+ T cells	Standard Deviation 0.007966
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0059520 percentage of CD4+ T cells	Standard Deviation 0.0099673
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0009887 percentage of CD4+ T cells	Standard Deviation 0.00117522
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.0051448 percentage of CD4+ T cells	Standard Deviation 0.00695615
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0063500 percentage of CD4+ T cells	Standard Deviation 0.01307177
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0040542 percentage of CD4+ T cells	Standard Deviation 0.0113173
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0233636 percentage of CD4+ T cells	Standard Deviation 0.04872838
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 15	0.0019248 percentage of CD4+ T cells	Standard Deviation 0.00358174
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 105	0.0147960 percentage of CD4+ T cells	Standard Deviation 0.02254635
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0009037 percentage of CD4+ T cells	Standard Deviation 0.00153323
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0092000 percentage of CD4+ T cells	Standard Deviation 0.01536808
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0192727 percentage of CD4+ T cells	Standard Deviation 0.03854372
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 105	0.0008000 percentage of CD4+ T cells	Standard Deviation 0.00130384
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0537778 percentage of CD4+ T cells	Standard Deviation 0.07350813
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0052020 percentage of CD4+ T cells	Standard Deviation 0.00685207
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0041111 percentage of CD4+ T cells	Standard Deviation 0.00669406
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0042078 percentage of CD4+ T cells	Standard Deviation 0.00647931
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0037906 percentage of CD4+ T cells	Standard Deviation 0.0047197
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0007457 percentage of CD4+ T cells	Standard Deviation 0.00106006
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0042653 percentage of CD4+ T cells	Standard Deviation 0.00817199
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0024256 percentage of CD4+ T cells	Standard Deviation 0.00231885
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0020605 percentage of CD4+ T cells	Standard Deviation 0.0015283
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0045455 percentage of CD4+ T cells	Standard Deviation 0.00706206
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 105	0.0011180 percentage of CD4+ T cells	Standard Deviation 0.00155249
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0049071 percentage of CD4+ T cells	Standard Deviation 0.00312169
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0131667 percentage of CD4+ T cells	Standard Deviation 0.0125975
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 105	0.0013000 percentage of CD4+ T cells	Standard Deviation 0.00209346
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0017842 percentage of CD4+ T cells	Standard Deviation 0.00228371
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 105	0.0009967 percentage of CD4+ T cells	Standard Deviation 0.001992
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 15	0.0184117 percentage of CD4+ T cells	Standard Deviation 0.02426237
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 15	0.0039595 percentage of CD4+ T cells	Standard Deviation 0.00434343
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 105	0.0066667 percentage of CD4+ T cells	Standard Deviation 0.0111475
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 105	0.0004400 percentage of CD4+ T cells	Standard Deviation 0.00061192
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0041551 percentage of CD4+ T cells	Standard Deviation 0.00511084
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0048095 percentage of CD4+ T cells	Standard Deviation 0.00757376
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 15	0.0022795 percentage of CD4+ T cells	Standard Deviation 0.00242556
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0110019 percentage of CD4+ T cells	Standard Deviation 0.01406371
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0077111 percentage of CD4+ T cells	Standard Deviation 0.00670335
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0012856 percentage of CD4+ T cells	Standard Deviation 0.0014562
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0055411 percentage of CD4+ T cells	Standard Deviation 0.00703655
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0043389 percentage of CD4+ T cells	Standard Deviation 0.00329533
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0019231 percentage of CD4+ T cells	Standard Deviation 0.00285971
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0058000 percentage of CD4+ T cells	Standard Deviation 0.00727803
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 105	0.0026940 percentage of CD4+ T cells	Standard Deviation 0.00293657
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0085371 percentage of CD4+ T cells	Standard Deviation 0.01020675
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0030009 percentage of CD4+ T cells	Standard Deviation 0.0044449
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 15	0.0330526 percentage of CD4+ T cells	Standard Deviation 0.05651693
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 15	0.0077311 percentage of CD4+ T cells	Standard Deviation 0.01847127
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0032105 percentage of CD4+ T cells	Standard Deviation 0.00491685
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0031367 percentage of CD4+ T cells	Standard Deviation 0.00432011
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 105	0.0016500 percentage of CD4+ T cells	Standard Deviation 0.00232157
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0038586 percentage of CD4+ T cells	Standard Deviation 0.01248055
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0029867 percentage of CD4+ T cells	Standard Deviation 0.00872447
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0006177 percentage of CD4+ T cells	Standard Deviation 0.0010289
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 15	0.0023851 percentage of CD4+ T cells	Standard Deviation 0.0034997
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0060424 percentage of CD4+ T cells	Standard Deviation 0.00716413
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.0099232 percentage of CD4+ T cells	Standard Deviation 0.01006738
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0607778 percentage of CD4+ T cells	Standard Deviation 0.06849777
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 15	0.0029114 percentage of CD4+ T cells	Standard Deviation 0.00457042
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.0041648 percentage of CD4+ T cells	Standard Deviation 0.00370931
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0014281 percentage of CD4+ T cells	Standard Deviation 0.00135883
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 105	0.0043583 percentage of CD4+ T cells	Standard Deviation 0.00586855
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 105	0.0062433 percentage of CD4+ T cells	Standard Deviation 0.0094073
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0088000 percentage of CD4+ T cells	Standard Deviation 0.01360392
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0028243 percentage of CD4+ T cells	Standard Deviation 0.00657932
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.0036216 percentage of CD4+ T cells	Standard Deviation 0.00439516
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 105	0.0007540 percentage of CD4+ T cells	Standard Deviation 0.001686
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0061967 percentage of CD4+ T cells	Standard Deviation 0.01073863
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0016830 percentage of CD4+ T cells	Standard Deviation 0.00264616
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0007918 percentage of CD4+ T cells	Standard Deviation 0.00151918
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 15	0.0020638 percentage of CD4+ T cells	Standard Deviation 0.00335443
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0102239 percentage of CD4+ T cells	Standard Deviation 0.02008526
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 105	0.0501960 percentage of CD4+ T cells	Standard Deviation 0.1005764
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0022368 percentage of CD4+ T cells	Standard Deviation 0.00317381
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 105	0.0013760 percentage of CD4+ T cells	Standard Deviation 0.00241658
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0027200 percentage of CD4+ T cells	Standard Deviation 0.00460175
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0023000 percentage of CD4+ T cells	Standard Deviation 0.00188396
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0010256 percentage of CD4+ T cells	Standard Deviation 0.00147028
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 105	0.0010760 percentage of CD4+ T cells	Standard Deviation 0.00089456
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0018854 percentage of CD4+ T cells	Standard Deviation 0.00346501
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0005916 percentage of CD4+ T cells	Standard Deviation 0.00126206
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 15	0.0024555 percentage of CD4+ T cells	Standard Deviation 0.00404542
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0023374 percentage of CD4+ T cells	Standard Deviation 0.00257822
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0006646 percentage of CD4+ T cells	Standard Deviation 0.00100992
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 105	0.0036640 percentage of CD4+ T cells	Standard Deviation 0.00370999
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0015773 percentage of CD4+ T cells	Standard Deviation 0.00239811
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0004526 percentage of CD4+ T cells	Standard Deviation 0.00059075
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 15	0.0027775 percentage of CD4+ T cells	Standard Deviation 0.00490646
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0034686 percentage of CD4+ T cells	Standard Deviation 0.004323
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0012968 percentage of CD4+ T cells	Standard Deviation 0.00161555
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 105	0.0015260 percentage of CD4+ T cells	Standard Deviation 0.00124341
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0015054 percentage of CD4+ T cells	Standard Deviation 0.00148462
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 15	0.0007662 percentage of CD4+ T cells	Standard Deviation 0.00172488
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0035320 percentage of CD4+ T cells	Standard Deviation 0.00412765
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0057832 percentage of CD4+ T cells	Standard Deviation 0.0201327
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0017955 percentage of CD4+ T cells	Standard Deviation 0.00255443
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	FNg-, IL2+, TNFa-, DENV-1, prME, Day 105	0.0046000 percentage of CD4+ T cells	Standard Deviation 0.00638749
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	FNg-, IL2+, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0057273 percentage of CD4+ T cells	Standard Deviation 0.00553337
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 15	0.0098571 percentage of CD4+ T cells	Standard Deviation 0.0243193
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 15	0.0156338 percentage of CD4+ T cells	Standard Deviation 0.01341318
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0069514 percentage of CD4+ T cells	Standard Deviation 0.00806641
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 105	0.0085950 percentage of CD4+ T cells	Standard Deviation 0.00881973
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0113109 percentage of CD4+ T cells	Standard Deviation 0.00863169
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0051673 percentage of CD4+ T cells	Standard Deviation 0.00437134
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0253419 percentage of CD4+ T cells	Standard Deviation 0.03739564
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0088740 percentage of CD4+ T cells	Standard Deviation 0.01159933
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0009544 percentage of CD4+ T cells	Standard Deviation 0.00127228
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0019966 percentage of CD4+ T cells	Standard Deviation 0.00189583
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0032012 percentage of CD4+ T cells	Standard Deviation 0.00384132
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 15	0.0075520 percentage of CD4+ T cells	Standard Deviation 0.00844484
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0018336 percentage of CD4+ T cells	Standard Deviation 0.00149423
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0007334 percentage of CD4+ T cells	Standard Deviation 0.00095378
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0087252 percentage of CD4+ T cells	Standard Deviation 0.01274292
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0041158 percentage of CD4+ T cells	Standard Deviation 0.00481914
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0105571 percentage of CD4+ T cells	Standard Deviation 0.00966628
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 105	0.0227280 percentage of CD4+ T cells	Standard Deviation 0.03716463
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0138388 percentage of CD4+ T cells	Standard Deviation 0.01736932
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 15	0.0006881 percentage of CD4+ T cells	Standard Deviation 0.0016378
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0064167 percentage of CD4+ T cells	Standard Deviation 0.01195034
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 15	0.0030952 percentage of CD4+ T cells	Standard Deviation 0.00770652
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0025714 percentage of CD4+ T cells	Standard Deviation 0.00517273
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0025252 percentage of CD4+ T cells	Standard Deviation 0.00822553
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0237273 percentage of CD4+ T cells	Standard Deviation 0.04557212
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0254118 percentage of CD4+ T cells	Standard Deviation 0.05545388
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0341782 percentage of CD4+ T cells	Standard Deviation 0.05499065
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0088750 percentage of CD4+ T cells	Standard Deviation 0.01786807
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0786250 percentage of CD4+ T cells	Standard Deviation 0.0767425
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0050500 percentage of CD4+ T cells	Standard Deviation 0.01240745
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0546667 percentage of CD4+ T cells	Standard Deviation 0.07867655
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0027715 percentage of CD4+ T cells	Standard Deviation 0.00491943
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 105	0.0011940 percentage of CD4+ T cells	Standard Deviation 0.00117362
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0020154 percentage of CD4+ T cells	Standard Deviation 0.00212428
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0004596 percentage of CD4+ T cells	Standard Deviation 0.00090723
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0009971 percentage of CD4+ T cells	Standard Deviation 0.00173995
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 15	0.0029003 percentage of CD4+ T cells	Standard Deviation 0.00272483
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 105	0.0037280 percentage of CD4+ T cells	Standard Deviation 0.00833606
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0070000 percentage of CD4+ T cells	Standard Deviation 0.01086278
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	FNg-, IL2+, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0095556 percentage of CD4+ T cells	Standard Deviation 0.01255101
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0122825 percentage of CD4+ T cells	Standard Deviation 0.01207005
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0114250 percentage of CD4+ T cells	Standard Deviation 0.00754569
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 15	0.0055626 percentage of CD4+ T cells	Standard Deviation 0.00618103
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0018340 percentage of CD4+ T cells	Standard Deviation 0.00213001
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0016511 percentage of CD4+ T cells	Standard Deviation 0.00156732
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 15	0.0195281 percentage of CD4+ T cells	Standard Deviation 0.01605864
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0129087 percentage of CD4+ T cells	Standard Deviation 0.01001686
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0074276 percentage of CD4+ T cells	Standard Deviation 0.0048759
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 105	0.0066833 percentage of CD4+ T cells	Standard Deviation 0.00676771
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0061417 percentage of CD4+ T cells	Standard Deviation 0.00294097
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 15	0.0122905 percentage of CD4+ T cells	Standard Deviation 0.01136975
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0086183 percentage of CD4+ T cells	Standard Deviation 0.00744631
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0029951 percentage of CD4+ T cells	Standard Deviation 0.00407349
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0180388 percentage of CD4+ T cells	Standard Deviation 0.01628354
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 105	0.0155460 percentage of CD4+ T cells	Standard Deviation 0.00736598
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0255438 percentage of CD4+ T cells	Standard Deviation 0.02222056
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0188425 percentage of CD4+ T cells	Standard Deviation 0.01749239
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0034200 percentage of CD4+ T cells	Standard Deviation 0.00296355
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0043200 percentage of CD4+ T cells	Standard Deviation 0.00603465
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 15	0.0066462 percentage of CD4+ T cells	Standard Deviation 0.00792826
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0033060 percentage of CD4+ T cells	Standard Deviation 0.00441884
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 105	0.0079900 percentage of CD4+ T cells	Standard Deviation 0.01211394
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0053583 percentage of CD4+ T cells	Standard Deviation 0.00565641
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 15	0.0015118 percentage of CD4+ T cells	Standard Deviation 0.00191718
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0021769 percentage of CD4+ T cells	Standard Deviation 0.00268205
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0010054 percentage of CD4+ T cells	Standard Deviation 0.00138756
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0006709 percentage of CD4+ T cells	Standard Deviation 0.00088977
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 15	0.0063455 percentage of CD4+ T cells	Standard Deviation 0.0070026
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 15	0.0020367 percentage of CD4+ T cells	Standard Deviation 0.00200211
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0009933 percentage of CD4+ T cells	Standard Deviation 0.00141721
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0005400 percentage of CD4+ T cells	Standard Deviation 0.00102516
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 15	0.0090109 percentage of CD4+ T cells	Standard Deviation 0.0085665
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0064879 percentage of CD4+ T cells	Standard Deviation 0.00601416
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0026280 percentage of CD4+ T cells	Standard Deviation 0.00337824
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 15	0.0063809 percentage of CD4+ T cells	Standard Deviation 0.00759632
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0031547 percentage of CD4+ T cells	Standard Deviation 0.00278886
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0009200 percentage of CD4+ T cells	Standard Deviation 0.00124907
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 15	0.0043954 percentage of CD4+ T cells	Standard Deviation 0.00510405
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0070050 percentage of CD4+ T cells	Standard Deviation 0.00365273
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0045850 percentage of CD4+ T cells	Standard Deviation 0.00682112
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0015112 percentage of CD4+ T cells	Standard Deviation 0.00306508
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 105	0.0011860 percentage of CD4+ T cells	Standard Deviation 0.0016311
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0013082 percentage of CD4+ T cells	Standard Deviation 0.00189986
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0036009 percentage of CD4+ T cells	Standard Deviation 0.00879474
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0080525 percentage of CD4+ T cells	Standard Deviation 0.01055229
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0034662 percentage of CD4+ T cells	Standard Deviation 0.00388476
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 105	0.0063400 percentage of CD4+ T cells	Standard Deviation 0.00932154
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0051208 percentage of CD4+ T cells	Standard Deviation 0.00397179
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0024600 percentage of CD4+ T cells	Standard Deviation 0.00277472
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 15	0.0020206 percentage of CD4+ T cells	Standard Deviation 0.0026039
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0020286 percentage of CD4+ T cells	Standard Deviation 0.00206735
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0009626 percentage of CD4+ T cells	Standard Deviation 0.00123421
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 105	0.0003300 percentage of CD4+ T cells	Standard Deviation 0.00056303
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0004290 percentage of CD4+ T cells	Standard Deviation 0.0007737
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0009997 percentage of CD4+ T cells	Standard Deviation 0.0012595
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 15	0.0101574 percentage of CD4+ T cells	Standard Deviation 0.01135027
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.0079673 percentage of CD4+ T cells	Standard Deviation 0.00830325
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.0039573 percentage of CD4+ T cells	Standard Deviation 0.00329832
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 105	0.0045767 percentage of CD4+ T cells	Standard Deviation 0.00294576
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.0035933 percentage of CD4+ T cells	Standard Deviation 0.00301672
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0016788 percentage of CD4+ T cells	Standard Deviation 0.00208657
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 15	0.0044780 percentage of CD4+ T cells	Standard Deviation 0.0069493
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.0044494 percentage of CD4+ T cells	Standard Deviation 0.00362591
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 105	0.0023333 percentage of CD4+ T cells	Standard Deviation 0.00297921
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0074518 percentage of CD4+ T cells	Standard Deviation 0.01318948
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0100288 percentage of CD4+ T cells	Standard Deviation 0.01429998
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0083430 percentage of CD4+ T cells	Standard Deviation 0.01049993
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0039411 percentage of CD4+ T cells	Standard Deviation 0.00506722
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 15	0.0006690 percentage of CD4+ T cells	Standard Deviation 0.00177413
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0037725 percentage of CD4+ T cells	Standard Deviation 0.00540746
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0016332 percentage of CD4+ T cells	Standard Deviation 0.00284966
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 105	0.0024340 percentage of CD4+ T cells	Standard Deviation 0.00417459
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0026618 percentage of CD4+ T cells	Standard Deviation 0.00395446
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 15	0.0026390 percentage of CD4+ T cells	Standard Deviation 0.00478957
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0022105 percentage of CD4+ T cells	Standard Deviation 0.00432793
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0040016 percentage of CD4+ T cells	Standard Deviation 0.01133985
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 105	0.0123960 percentage of CD4+ T cells	Standard Deviation 0.01897351
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0055455 percentage of CD4+ T cells	Standard Deviation 0.008311
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0028073 percentage of CD4+ T cells	Standard Deviation 0.00241349
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0034077 percentage of CD4+ T cells	Standard Deviation 0.00388535
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 15	0.0010586 percentage of CD4+ T cells	Standard Deviation 0.0012343
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0015226 percentage of CD4+ T cells	Standard Deviation 0.00145884
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0013921 percentage of CD4+ T cells	Standard Deviation 0.0014657
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 105	0.0020120 percentage of CD4+ T cells	Standard Deviation 0.00343865
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0016538 percentage of CD4+ T cells	Standard Deviation 0.00147798
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0005131 percentage of CD4+ T cells	Standard Deviation 0.00105742
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 15	0.0019679 percentage of CD4+ T cells	Standard Deviation 0.0022643
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0014351 percentage of CD4+ T cells	Standard Deviation 0.00201558
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0005243 percentage of CD4+ T cells	Standard Deviation 0.00078972
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 105	0.0021520 percentage of CD4+ T cells	Standard Deviation 0.00374127
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0010900 percentage of CD4+ T cells	Standard Deviation 0.00094653
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0009091 percentage of CD4+ T cells	Standard Deviation 0.00135131
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 15	0.0021766 percentage of CD4+ T cells	Standard Deviation 0.00325195
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0019537 percentage of CD4+ T cells	Standard Deviation 0.00217059
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0011930 percentage of CD4+ T cells	Standard Deviation 0.00181994
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 105	0.0013140 percentage of CD4+ T cells	Standard Deviation 0.00138036
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0009293 percentage of CD4+ T cells	Standard Deviation 0.00129407
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0006534 percentage of CD4+ T cells	Standard Deviation 0.00095082
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 15	0.0010538 percentage of CD4+ T cells	Standard Deviation 0.00210085
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0053990 percentage of CD4+ T cells	Standard Deviation 0.00689308
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0027358 percentage of CD4+ T cells	Standard Deviation 0.00322179
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 105	0.0014640 percentage of CD4+ T cells	Standard Deviation 0.00259932
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0057182 percentage of CD4+ T cells	Standard Deviation 0.00781389
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0034000 percentage of CD4+ T cells	Standard Deviation 0.00501189
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 15	0.0048771 percentage of CD4+ T cells	Standard Deviation 0.00855424
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0055520 percentage of CD4+ T cells	Standard Deviation 0.00738344
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 105	0.0006000 percentage of CD4+ T cells	Standard Deviation 0.00134164
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0093636 percentage of CD4+ T cells	Standard Deviation 0.01344078
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0072222 percentage of CD4+ T cells	Standard Deviation 0.01328324
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 15	0.0128095 percentage of CD4+ T cells	Standard Deviation 0.02841939
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0137000 percentage of CD4+ T cells	Standard Deviation 0.02625202
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0117384 percentage of CD4+ T cells	Standard Deviation 0.01908793
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 105	0.0123960 percentage of CD4+ T cells	Standard Deviation 0.01978191
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0190000 percentage of CD4+ T cells	Standard Deviation 0.02560078
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0013000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 15	0.0069450 percentage of CD4+ T cells	Standard Deviation 0.00426385
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 105	0.0029100 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0006150 percentage of CD4+ T cells	Standard Deviation 0.00086974
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0012900 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0200000 percentage of CD4+ T cells	Standard Deviation 0.02828427
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 15	0.0345000 percentage of CD4+ T cells	Standard Deviation 0.02757716
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0013200 percentage of CD4+ T cells	Standard Deviation 0.00186676
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0110000 percentage of CD4+ T cells	Standard Deviation 0.01555635
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0101050 percentage of CD4+ T cells	Standard Deviation 0.01051468
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0113650 percentage of CD4+ T cells	Standard Deviation 0.01014698
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0000200 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 15	0.0166300 percentage of CD4+ T cells	Standard Deviation 0.01466539
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0184670 percentage of CD4+ T cells	Standard Deviation 0.02212254
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0030300 percentage of CD4+ T cells	Standard Deviation 0.00428507
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 105	0.0028600 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0250000 percentage of CD4+ T cells	Standard Deviation 0.03535534
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0000500 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 15	0.0072000 percentage of CD4+ T cells	Standard Deviation 0.0002687
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0261400 percentage of CD4+ T cells	Standard Deviation 0.01677257
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 105	0.0304700 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0106670 percentage of CD4+ T cells	Standard Deviation 0.00471357
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 105	0.0036000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0049350 percentage of CD4+ T cells	Standard Deviation 0.00509824
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0000300 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0009150 percentage of CD4+ T cells	Standard Deviation 0.00129401
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 15	0.0084785 percentage of CD4+ T cells	Standard Deviation 0.01063701
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0041720 percentage of CD4+ T cells	Standard Deviation 0.00065337
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0017200 percentage of CD4+ T cells	Standard Deviation 0.00243245
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 105	0.0000390 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0013750 percentage of CD4+ T cells	Standard Deviation 0.00194454
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 15	0.0015700 percentage of CD4+ T cells	Standard Deviation 0.00222032
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 15	0.0030000 percentage of CD4+ T cells	Standard Deviation 0.00282843
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0047200 percentage of CD4+ T cells	Standard Deviation 0.00667509
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0013500 percentage of CD4+ T cells	Standard Deviation 0.00002828
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 15	0.0119550 percentage of CD4+ T cells	Standard Deviation 0.01460176
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0047720 percentage of CD4+ T cells	Standard Deviation 0.00660155
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0006150 percentage of CD4+ T cells	Standard Deviation 0.00086974
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 15	0.0298850 percentage of CD4+ T cells	Standard Deviation 0.02884289
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 15	0.0543850 percentage of CD4+ T cells	Standard Deviation 0.05359162
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0269820 percentage of CD4+ T cells	Standard Deviation 0.03538079
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0030000 percentage of CD4+ T cells	Standard Deviation 0.00424264
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0349770 percentage of CD4+ T cells	Standard Deviation 0.04811579
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 15	0.0236700 percentage of CD4+ T cells	Standard Deviation 0.03338958
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0170245 percentage of CD4+ T cells	Standard Deviation 0.02400698
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0062700 percentage of CD4+ T cells	Standard Deviation 0.00886712
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0102600 percentage of CD4+ T cells	Standard Deviation 0.01450983
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0165400 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0245000 percentage of CD4+ T cells	Standard Deviation 0.03464823
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 105	0.0012200 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0077600 percentage of CD4+ T cells	Standard Deviation 0.0109743
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0750000 percentage of CD4+ T cells	Standard Deviation 0.10606602
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0134350 percentage of CD4+ T cells	Standard Deviation 0.01711906
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0082700 percentage of CD4+ T cells	Standard Deviation 0.01169555
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0055700 percentage of CD4+ T cells	Standard Deviation 0.00255973
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 105	0.0100000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0030950 percentage of CD4+ T cells	Standard Deviation 0.00437699
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 105	0.0017500 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0021100 percentage of CD4+ T cells	Standard Deviation 0.00104652
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0013000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 15	0.0180950 percentage of CD4+ T cells	Standard Deviation 0.00296278
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 15	0.0042250 percentage of CD4+ T cells	Standard Deviation 0.00290621
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0016200 percentage of CD4+ T cells	Standard Deviation 0.00229103
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0150950 percentage of CD4+ T cells	Standard Deviation 0.02123442
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0000400 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0600000 percentage of CD4+ T cells	Standard Deviation 0.08485281
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0050000 percentage of CD4+ T cells	Standard Deviation 0.00707107
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0023500 percentage of CD4+ T cells	Standard Deviation 0.0033234
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 15	0.0455950 percentage of CD4+ T cells	Standard Deviation 0.00084146
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 105	0.0024200 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0108200 percentage of CD4+ T cells	Standard Deviation 0.00950352
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0025300 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0029000 percentage of CD4+ T cells	Standard Deviation 0.00410122
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.0056000 percentage of CD4+ T cells	Standard Deviation 0.0063781
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 105	0.0000600 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0006950 percentage of CD4+ T cells	Standard Deviation 0.00098288
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.0031250 percentage of CD4+ T cells	Standard Deviation 0.004278
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 15	0.0196200 percentage of CD4+ T cells	Standard Deviation 0.02214658
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0230380 percentage of CD4+ T cells	Standard Deviation 0.03247317
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 105	0.0005200 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0077600 percentage of CD4+ T cells	Standard Deviation 0.0109743
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0087700 percentage of CD4+ T cells	Standard Deviation 0.01240265
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.0031800 percentage of CD4+ T cells	Standard Deviation 0.00055154
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 15	0.0013760 percentage of CD4+ T cells	Standard Deviation 0.00084004
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0400000 percentage of CD4+ T cells	Standard Deviation 0.05656854
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0065550 percentage of CD4+ T cells	Standard Deviation 0.00927017
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0012300 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0055000 percentage of CD4+ T cells	Standard Deviation 0.00777817
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 105	0.0018300 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0019950 percentage of CD4+ T cells	Standard Deviation 0.00094045
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0013500 percentage of CD4+ T cells	Standard Deviation 0.00002828
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 15	0.0130950 percentage of CD4+ T cells	Standard Deviation 0.00154856
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 15	0.0030100 percentage of CD4+ T cells	Standard Deviation 0.00425678
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0050000 percentage of CD4+ T cells	Standard Deviation 0.00707107
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.0060550 percentage of CD4+ T cells	Standard Deviation 0.00856306
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0041500 percentage of CD4+ T cells	Standard Deviation 0.00586899
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0060000 percentage of CD4+ T cells	Standard Deviation 0.00848528
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0025000 percentage of CD4+ T cells	Standard Deviation 0.00353553
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	FNg-, IL2+, TNFa-, DENV-1, prME, Day 105	0.0100000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	FNg-, IL2+, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	FNg-, IL2+, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 15	0.0250000 percentage of CD4+ T cells	Standard Deviation 0.03535534
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0400000 percentage of CD4+ T cells	Standard Deviation 0.05656854
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 15	0.0345000 percentage of CD4+ T cells	Standard Deviation 0.00070711
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0024950 percentage of CD4+ T cells	Standard Deviation 0.00133643
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0010000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0339320 percentage of CD4+ T cells	Standard Deviation 0.03984971
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0090000 percentage of CD4+ T cells	Standard Deviation 0.00282843
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0681170 percentage of CD4+ T cells	Standard Deviation 0.01978909
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 15	0.0097000 percentage of CD4+ T cells	Standard Deviation 0.00608112
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 105	0.0050000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0000200 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0020000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 15	0.0330950 percentage of CD4+ T cells	Standard Deviation 0.02107885
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0075900 percentage of CD4+ T cells	Standard Deviation 0.00639225
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 15	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 15	0.0035100 percentage of CD4+ T cells	Standard Deviation 0.00352139
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0120000 percentage of CD4+ T cells	Standard Deviation 0.00989949
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0075000 percentage of CD4+ T cells	Standard Deviation 0.0106066
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0200000 percentage of CD4+ T cells	Standard Deviation 0.02828427
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 15	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 15	0.0850000 percentage of CD4+ T cells	Standard Deviation 0.12020815
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0300000 percentage of CD4+ T cells	Standard Deviation 0.04242641
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 105	0.0100000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 15	0.0450000 percentage of CD4+ T cells	Standard Deviation 0.06363961
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0500000 percentage of CD4+ T cells	Standard Deviation 0.07071068
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 15	0.1150000 percentage of CD4+ T cells	Standard Deviation 0.16263456
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0450000 percentage of CD4+ T cells	Standard Deviation 0.06363961
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 15	0.0017650 percentage of CD4+ T cells	Standard Deviation 0.00249609
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0010000 percentage of CD4+ T cells	Standard Deviation 0.00141421
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 105	0.0000290 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0013950 percentage of CD4+ T cells	Standard Deviation 0.00007778
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0012300 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0000400 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 15	0.0300000 percentage of CD4+ T cells	Standard Deviation 0.04242641
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0126170 percentage of CD4+ T cells	Standard Deviation 0.00213122
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 105	0.0080000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 105	0.0284700 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 105	0.0200000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 15	0.0450000 percentage of CD4+ T cells	Standard Deviation 0.06363961
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 15	0.0200000 percentage of CD4+ T cells	Standard Deviation 0.02828427
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 15	0.0132800 percentage of CD4+ T cells	Standard Deviation 0.01657458
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0008700 percentage of CD4+ T cells	Standard Deviation 0.00123037
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0154820 percentage of CD4+ T cells	Standard Deviation 0.02053155
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0150000 percentage of CD4+ T cells	Standard Deviation 0.0212132
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0010000 percentage of CD4+ T cells	Standard Deviation 0.00141421
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0060000 percentage of CD4+ T cells	Standard Deviation 0.00141421
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0050000 percentage of CD4+ T cells	Standard Deviation 0.00707107
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 15	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0050000 percentage of CD4+ T cells	Standard Deviation 0.00707107
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 105	0.0400000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0100000 percentage of CD4+ T cells	Standard Deviation 0.01414214
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0250000 percentage of CD4+ T cells	Standard Deviation 0.03535534
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0850000 percentage of CD4+ T cells	Standard Deviation 0.12020815
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 105	0.0200000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0200000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0200000 percentage of CD4+ T cells	Standard Deviation 0.02828427
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0224970 percentage of CD4+ T cells	Standard Deviation 0.02915118
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0073800 percentage of CD4+ T cells	Standard Deviation 0.00794788
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 105	0.0005900 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0072700 percentage of CD4+ T cells	Standard Deviation 0.01028133
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0084820 percentage of CD4+ T cells	Standard Deviation 0.01063206
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 15	0.0194500 percentage of CD4+ T cells	Standard Deviation 0.02521543
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 15	0.0010000 percentage of CD4+ T cells	Standard Deviation 0.00141421
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0145000 percentage of CD4+ T cells	Standard Deviation 0.0205061
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0070200 percentage of CD4+ T cells	Standard Deviation 0.00021213
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0058220 percentage of CD4+ T cells	Standard Deviation 0.0002291
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0024550 percentage of CD4+ T cells	Standard Deviation 0.00338704
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0049750 percentage of CD4+ T cells	Standard Deviation 0.00504167
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 15	0.0855000 percentage of CD4+ T cells	Standard Deviation 0.01202082
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0345400 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0208000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0215985 percentage of CD4+ T cells	Standard Deviation 0.03042186
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0075000 percentage of CD4+ T cells	Standard Deviation 0.0106066
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0025000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0000650 percentage of CD4+ T cells	Standard Deviation 0.00009192
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 15	0.0061800 percentage of CD4+ T cells	Standard Deviation 0.00004243
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.0043520 percentage of CD4+ T cells	Standard Deviation 0.00203364
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.0016750 percentage of CD4+ T cells	Standard Deviation 0.00013435
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 105	0.0005200 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.0012550 percentage of CD4+ T cells	Standard Deviation 0.00177484
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0012200 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 15	0.0011750 percentage of CD4+ T cells	Standard Deviation 0.0016617
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.0027520 percentage of CD4+ T cells	Standard Deviation 0.0012134
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.0007700 percentage of CD4+ T cells	Standard Deviation 0.00108894
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.0014300 percentage of CD4+ T cells	Standard Deviation 0.00202233
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 15	0.0276900 percentage of CD4+ T cells	Standard Deviation 0.03013689
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0124520 percentage of CD4+ T cells	Standard Deviation 0.00519299
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0107550 percentage of CD4+ T cells	Standard Deviation 0.00034648
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 105	0.0081900 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0014200 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0130000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 15	0.0034600 percentage of CD4+ T cells	Standard Deviation 0.00052326
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0030320 percentage of CD4+ T cells	Standard Deviation 0.00143967
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0029050 percentage of CD4+ T cells	Standard Deviation 0.00410829
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0014450 percentage of CD4+ T cells	Standard Deviation 0.00204354
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0012300 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 15	0.0428850 percentage of CD4+ T cells	Standard Deviation 0.01611496
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0185620 percentage of CD4+ T cells	Standard Deviation 0.01051892
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0032600 percentage of CD4+ T cells	Standard Deviation 0.00217789
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 105	0.0045900 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0035500 percentage of CD4+ T cells	Standard Deviation 0.00308299
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0018050 percentage of CD4+ T cells	Standard Deviation 0.00255266
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 105	0.0000430 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0067600 percentage of CD4+ T cells	Standard Deviation 0.00956008
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0062700 percentage of CD4+ T cells	Standard Deviation 0.00886712
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0007900 percentage of CD4+ T cells	Standard Deviation 0.00111723
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 105	0.0017300 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 15	0.0878850 percentage of CD4+ T cells	Standard Deviation 0.01328654
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0505620 percentage of CD4+ T cells	Standard Deviation 0.00486207
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0224000 percentage of CD4+ T cells	Standard Deviation 0.00582656
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0188000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 15	0.0270400 percentage of CD4+ T cells	Standard Deviation 0.03710896
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.0037850 percentage of CD4+ T cells	Standard Deviation 0.0053528
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 105	0.0011700 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 15	0.0915950 percentage of CD4+ T cells	Standard Deviation 0.08259714
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0441800 percentage of CD4+ T cells	Standard Deviation 0.02979748
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0197800 percentage of CD4+ T cells	Standard Deviation 0.0124168
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 105	0.0087000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0138000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 15	0.0039900 percentage of CD4+ T cells	Standard Deviation 0.00127279
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0029200 percentage of CD4+ T cells	Standard Deviation 0.0041295
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 105	0.0006500 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0006650 percentage of CD4+ T cells	Standard Deviation 0.00094045
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0000300 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 15	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0014550 percentage of CD4+ T cells	Standard Deviation 0.00205768
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0010000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 15	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0115000 percentage of CD4+ T cells	Standard Deviation 0.00636396
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0051500 percentage of CD4+ T cells	Standard Deviation 0.0072832
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 15	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0030000 percentage of CD4+ T cells	Standard Deviation 0.00424264
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 105	0.0010000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0056500 percentage of CD4+ T cells	Standard Deviation 0.00799031
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 15	0.0040100 percentage of CD4+ T cells	Standard Deviation 0.005671
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0015750 percentage of CD4+ T cells	Standard Deviation 0.00222739
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 15	0.0080100 percentage of CD4+ T cells	Standard Deviation 0.00425678
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0031500 percentage of CD4+ T cells	Standard Deviation 0.00445477
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 15	0.0010000 percentage of CD4+ T cells	Standard Deviation 0.00141421
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0010000 percentage of CD4+ T cells	Standard Deviation 0.00141421
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0055000 percentage of CD4+ T cells	Standard Deviation 0.00212132
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 105	0.0090000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 15	0.0005000 percentage of CD4+ T cells	Standard Deviation 0.00070711
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0190000 percentage of CD4+ T cells	Standard Deviation 0.02687006
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0050000 percentage of CD4+ T cells	Standard Deviation 0.00707107
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 15	0.0030000 percentage of CD4+ T cells	Standard Deviation 0.00424264
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.0035000 percentage of CD4+ T cells	Standard Deviation 0.00494975
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 15	0.0030000 percentage of CD4+ T cells	Standard Deviation 0.00424264
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.0015000 percentage of CD4+ T cells	Standard Deviation 0.00212132
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.0080000 percentage of CD4+ T cells	Standard Deviation 0.01131371
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 15	0.0010000 percentage of CD4+ T cells	Standard Deviation 0.00141421
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0075000 percentage of CD4+ T cells	Standard Deviation 0.0106066
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0225000 percentage of CD4+ T cells	Standard Deviation 0.00494975
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 105	0.0270000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 15	0.0005000 percentage of CD4+ T cells	Standard Deviation 0.00070711
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0050000 percentage of CD4+ T cells	Standard Deviation 0.00707107
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 15	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0057600 percentage of CD4+ T cells	Standard Deviation 0.00814587
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0057700 percentage of CD4+ T cells	Standard Deviation 0.00816001
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 15	0.0054855 percentage of CD4+ T cells	Standard Deviation 0.00665317
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0025200 percentage of CD4+ T cells	Standard Deviation 0.00213546
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0023950 percentage of CD4+ T cells	Standard Deviation 0.00338704
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 105	0.0005900 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0021700 percentage of CD4+ T cells	Standard Deviation 0.00306884
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0000300 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0006850 percentage of CD4+ T cells	Standard Deviation 0.00096874
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 15	0.0030000 percentage of CD4+ T cells	Standard Deviation 0.00424264
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0085000 percentage of CD4+ T cells	Standard Deviation 0.01202082
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 105	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0020000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 15	0.0280000 percentage of CD4+ T cells	Standard Deviation 0.01272792
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0273970 percentage of CD4+ T cells	Standard Deviation 0.03353525
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0120550 percentage of CD4+ T cells	Standard Deviation 0.01689278
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 105	0.0064500 percentage of CD4+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 15	0.0190000 percentage of CD4+ T cells	Standard Deviation 0.01272792
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0235670 percentage of CD4+ T cells	Standard Deviation 0.03188062
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 15	0.0017250 percentage of CD4+ T cells	Standard Deviation 0.00023335
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0109800 percentage of CD4+ T cells	Standard Deviation 0.00962191
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0200000 percentage of CD4+ T cells	Standard Deviation 0.01272792
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.0085767 percentage of CD4+ T cells	Standard Deviation 0.00753694
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0025000 percentage of CD4+ T cells	Standard Deviation 0.00353553
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 15	0.0095367 percentage of CD4+ T cells	Standard Deviation 0.01244163
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 15	0.0146700 percentage of CD4+ T cells	Standard Deviation 0.01675231
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0140600 percentage of CD4+ T cells	Standard Deviation 0.01672199
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0081633 percentage of CD4+ T cells	Standard Deviation 0.00851998
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 105	0.0005400 percentage of CD4+ T cells	Standard Deviation 0.00093531
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0005967 percentage of CD4+ T cells	Standard Deviation 0.00103346
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0050000 percentage of CD4+ T cells	Standard Deviation 0.00707107
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0053133 percentage of CD4+ T cells	Standard Deviation 0.00920296
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0008885 percentage of CD4+ T cells	Standard Deviation 0.00125653
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0770000 percentage of CD4+ T cells	Standard Deviation 0.00989949
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 15	0.0044800 percentage of CD4+ T cells	Standard Deviation 0.00577678
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0026010 percentage of CD4+ T cells	Standard Deviation 0.00178568
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 105	0.0164733 percentage of CD4+ T cells	Standard Deviation 0.01680245
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 105	0.0019900 percentage of CD4+ T cells	Standard Deviation 0.00262874
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0064033 percentage of CD4+ T cells	Standard Deviation 0.00380907
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0413333 percentage of CD4+ T cells	Standard Deviation 0.04006661
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0023100 percentage of CD4+ T cells	Standard Deviation 0.00400104
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0106660 percentage of CD4+ T cells	Standard Deviation 0.00795335
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 105	0.0433333 percentage of CD4+ T cells	Standard Deviation 0.07505553
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0145877 percentage of CD4+ T cells	Standard Deviation 0.01618069
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 15	0.0055700 percentage of CD4+ T cells	Standard Deviation 0.00649882
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 15	0.0175233 percentage of CD4+ T cells	Standard Deviation 0.01552713
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 105	0.1293333 percentage of CD4+ T cells	Standard Deviation 0.19110556
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0033333 percentage of CD4+ T cells	Standard Deviation 0.0057735
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0046440 percentage of CD4+ T cells	Standard Deviation 0.00532593
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0580000 percentage of CD4+ T cells	Standard Deviation 0.05031898
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0146667 percentage of CD4+ T cells	Standard Deviation 0.01616581
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 15	0.0023033 percentage of CD4+ T cells	Standard Deviation 0.00268712
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0019985 percentage of CD4+ T cells	Standard Deviation 0.00102036
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 105	0.0086667 percentage of CD4+ T cells	Standard Deviation 0.01078579
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0027600 percentage of CD4+ T cells	Standard Deviation 0.00079265
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0880000 percentage of CD4+ T cells	Standard Deviation 0.07830709
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0056667 percentage of CD4+ T cells	Standard Deviation 0.00550757
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0020033 percentage of CD4+ T cells	Standard Deviation 0.00186162
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0081633 percentage of CD4+ T cells	Standard Deviation 0.00851998
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 15	0.0347667 percentage of CD4+ T cells	Standard Deviation 0.03185692
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 15	0.0032367 percentage of CD4+ T cells	Standard Deviation 0.00302788
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0065793 percentage of CD4+ T cells	Standard Deviation 0.00473908
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0009250 percentage of CD4+ T cells	Standard Deviation 0.00130815
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0066667 percentage of CD4+ T cells	Standard Deviation 0.01154701
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0100000 percentage of CD4+ T cells	Standard Deviation 0.01732051
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0173333 percentage of CD4+ T cells	Standard Deviation 0.02746513
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0580000 percentage of CD4+ T cells	Standard Deviation 0.06009992
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0119560 percentage of CD4+ T cells	Standard Deviation 0.00976035
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 105	0.0010000 percentage of CD4+ T cells	Standard Deviation 0.00173205
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 105	0.0733333 percentage of CD4+ T cells	Standard Deviation 0.11846237
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0010800 percentage of CD4+ T cells	Standard Deviation 0.00183608
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0310000 percentage of CD4+ T cells	Standard Deviation 0.04293018
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0250000 percentage of CD4+ T cells	Standard Deviation 0.03535534
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 15	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0050000 percentage of CD4+ T cells	Standard Deviation 0.005
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0028307 percentage of CD4+ T cells	Standard Deviation 0.00290989
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.0130000 percentage of CD4+ T cells	Standard Deviation 0.00556776
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 15	0.0009033 percentage of CD4+ T cells	Standard Deviation 0.00156462
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 15	0.0013133 percentage of CD4+ T cells	Standard Deviation 0.00119605
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.0043333 percentage of CD4+ T cells	Standard Deviation 0.00585947
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 15	0.0487733 percentage of CD4+ T cells	Standard Deviation 0.0494481
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 105	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 105	0.0016667 percentage of CD4+ T cells	Standard Deviation 0.00288675
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0009050 percentage of CD4+ T cells	Standard Deviation 0.00127986
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 105	0.0047467 percentage of CD4+ T cells	Standard Deviation 0.00638064
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.0116667 percentage of CD4+ T cells	Standard Deviation 0.01386843
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0011827 percentage of CD4+ T cells	Standard Deviation 0.00198127
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 15	0.0476667 percentage of CD4+ T cells	Standard Deviation 0.06368935
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0040000 percentage of CD4+ T cells	Standard Deviation 0.00565685
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0016910 percentage of CD4+ T cells	Standard Deviation 0.00108924
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0053333 percentage of CD4+ T cells	Standard Deviation 0.0092376
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 15	0.0082367 percentage of CD4+ T cells	Standard Deviation 0.01120795
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 15	0.0027067 percentage of CD4+ T cells	Standard Deviation 0.002045
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0043733 percentage of CD4+ T cells	Standard Deviation 0.00330736
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.0030000 percentage of CD4+ T cells	Standard Deviation 0.003
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0065440 percentage of CD4+ T cells	Standard Deviation 0.00147927
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 105	0.0013333 percentage of CD4+ T cells	Standard Deviation 0.0023094
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.0063333 percentage of CD4+ T cells	Standard Deviation 0.0070946
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0087367 percentage of CD4+ T cells	Standard Deviation 0.01165157
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 15	0.0010800 percentage of CD4+ T cells	Standard Deviation 0.00175923
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 105	0.0010000 percentage of CD4+ T cells	Standard Deviation 0.00173205
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 105	0.0065467 percentage of CD4+ T cells	Standard Deviation 0.00607425
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0045693 percentage of CD4+ T cells	Standard Deviation 0.00367278
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.0003333 percentage of CD4+ T cells	Standard Deviation 0.00057735
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0066433 percentage of CD4+ T cells	Standard Deviation 0.00434298
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0020133 percentage of CD4+ T cells	Standard Deviation 0.0034872
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0155000 percentage of CD4+ T cells	Standard Deviation 0.02192031
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0166927 percentage of CD4+ T cells	Standard Deviation 0.02121306
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 15	0.0126667 percentage of CD4+ T cells	Standard Deviation 0.02193931
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 15	0.0140067 percentage of CD4+ T cells	Standard Deviation 0.02424294
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.1373333 percentage of CD4+ T cells	Standard Deviation 0.0824702
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0056667 percentage of CD4+ T cells	Standard Deviation 0.0051316
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0906667 percentage of CD4+ T cells	Standard Deviation 0.05138417
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 15	0.0024367 percentage of CD4+ T cells	Standard Deviation 0.00211519
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0031343 percentage of CD4+ T cells	Standard Deviation 0.00307798
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0019185 percentage of CD4+ T cells	Standard Deviation 0.00261842
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0035200 percentage of CD4+ T cells	Standard Deviation 0.0030521
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0001920 percentage of CD4+ T cells	Standard Deviation 0.00033255
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0100000 percentage of CD4+ T cells	Standard Deviation 0.00916515
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0014500 percentage of CD4+ T cells	Standard Deviation 0.0014601
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0022035 percentage of CD4+ T cells	Standard Deviation 0.00064559
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0233333 percentage of CD4+ T cells	Standard Deviation 0.04041452
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0048743 percentage of CD4+ T cells	Standard Deviation 0.00332532
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 30 (Month 1)	0.1506667 percentage of CD4+ T cells	Standard Deviation 0.07759725
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0078667 percentage of CD4+ T cells	Standard Deviation 0.00525903
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0255367 percentage of CD4+ T cells	Standard Deviation 0.02610415
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0250400 percentage of CD4+ T cells	Standard Deviation 0.0305544
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.0013160 percentage of CD4+ T cells	Standard Deviation 0.00044863
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 105	0.0018267 percentage of CD4+ T cells	Standard Deviation 0.00165908
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 105	0.0026667 percentage of CD4+ T cells	Standard Deviation 0.0046188
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.0002120 percentage of CD4+ T cells	Standard Deviation 0.00036719
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0002240 percentage of CD4+ T cells	Standard Deviation 0.00038798
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 105	0.0005267 percentage of CD4+ T cells	Standard Deviation 0.00091221
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0027843 percentage of CD4+ T cells	Standard Deviation 0.00263947
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 15	0.0976667 percentage of CD4+ T cells	Standard Deviation 0.05173329
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.0011733 percentage of CD4+ T cells	Standard Deviation 0.00203227
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 105	0.0056000 percentage of CD4+ T cells	Standard Deviation 0.00592666
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0116667 percentage of CD4+ T cells	Standard Deviation 0.00776745
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0004310 percentage of CD4+ T cells	Standard Deviation 0.00060953
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0057033 percentage of CD4+ T cells	Standard Deviation 0.00286514
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0846667 percentage of CD4+ T cells	Standard Deviation 0.10346658
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 15	0.0062000 percentage of CD4+ T cells	Standard Deviation 0.00563205
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0079800 percentage of CD4+ T cells	Standard Deviation 0.0057549
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0336667 percentage of CD4+ T cells	Standard Deviation 0.0414769
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0015410 percentage of CD4+ T cells	Standard Deviation 0.00085791
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 15	0.0240633 percentage of CD4+ T cells	Standard Deviation 0.03025849
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0060000 percentage of CD4+ T cells	Standard Deviation 0.0087178
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0011100 percentage of CD4+ T cells	Standard Deviation 0.00192258
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0004275 percentage of CD4+ T cells	Standard Deviation 0.00058336
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0360000 percentage of CD4+ T cells	Standard Deviation 0.01272792
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 105	0.0010400 percentage of CD4+ T cells	Standard Deviation 0.00180133
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0012343 percentage of CD4+ T cells	Standard Deviation 0.00133427
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0996667 percentage of CD4+ T cells	Standard Deviation 0.11571661
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0003600 percentage of CD4+ T cells	Standard Deviation 0.00062354
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 105	0.0020167 percentage of CD4+ T cells	Standard Deviation 0.00116453
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0173333 percentage of CD4+ T cells	Standard Deviation 0.03002221
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0005985 percentage of CD4+ T cells	Standard Deviation 0.00084641
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0034137 percentage of CD4+ T cells	Standard Deviation 0.00278951
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 15	0.0094100 percentage of CD4+ T cells	Standard Deviation 0.0152458
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 15	0.0442107 percentage of CD4+ T cells	Standard Deviation 0.04821126
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0044700 percentage of CD4+ T cells	Standard Deviation 0.00201167
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0092893 percentage of CD4+ T cells	Standard Deviation 0.009507
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 15	0.0049867 percentage of CD4+ T cells	Standard Deviation 0.0055714
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 15	0.0710000 percentage of CD4+ T cells	Standard Deviation 0.05179768
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0020720 percentage of CD4+ T cells	Standard Deviation 0.00091517
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0013275 percentage of CD4+ T cells	Standard Deviation 0.00066397
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 15	0.0156033 percentage of CD4+ T cells	Standard Deviation 0.01522844
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 105	0.0022200 percentage of CD4+ T cells	Standard Deviation 0.00384515
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0060000 percentage of CD4+ T cells	Standard Deviation 0.00519615
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0004200 percentage of CD4+ T cells	Standard Deviation 0.00059397
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0006143 percentage of CD4+ T cells	Standard Deviation 0.00065878
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 105	0.0133333 percentage of CD4+ T cells	Standard Deviation 0.02309401
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 15	0.0064967 percentage of CD4+ T cells	Standard Deviation 0.0080985
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0004767 percentage of CD4+ T cells	Standard Deviation 0.00082561
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 105	0.0015767 percentage of CD4+ T cells	Standard Deviation 0.00273087
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0113333 percentage of CD4+ T cells	Standard Deviation 0.01962991
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0303333 percentage of CD4+ T cells	Standard Deviation 0.05253887
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0009733 percentage of CD4+ T cells	Standard Deviation 0.00168586
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0020000 percentage of CD4+ T cells	Standard Deviation 0.0034641
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 105	0.0096600 percentage of CD4+ T cells	Standard Deviation 0.01002032
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0025633 percentage of CD4+ T cells	Standard Deviation 0.00102627
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0340000 percentage of CD4+ T cells	Standard Deviation 0.02404163
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0101467 percentage of CD4+ T cells	Standard Deviation 0.0171949
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 15	0.0023867 percentage of CD4+ T cells	Standard Deviation 0.00266356
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 105	0.0010000 percentage of CD4+ T cells	Standard Deviation 0.00173205
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0003085 percentage of CD4+ T cells	Standard Deviation 0.00043628
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 105	0.0466667 percentage of CD4+ T cells	Standard Deviation 0.07234178
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 15	0.0019433 percentage of CD4+ T cells	Standard Deviation 0.00336595
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.0001777 percentage of CD4+ T cells	Standard Deviation 0.00030773
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0600000 percentage of CD4+ T cells	Standard Deviation 0.08485281
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0010000 percentage of CD4+ T cells	Standard Deviation 0.00173205
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 105	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.0001920 percentage of CD4+ T cells	Standard Deviation 0.00033255
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0026667 percentage of CD4+ T cells	Standard Deviation 0.0046188
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 105	0.0003333 percentage of CD4+ T cells	Standard Deviation 0.00057735
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.0020900 percentage of CD4+ T cells	Standard Deviation 0.00092677
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0026467 percentage of CD4+ T cells	Standard Deviation 0.00458416
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 15	0.0062000 percentage of CD4+ T cells	Standard Deviation 0.00507572
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0080000 percentage of CD4+ T cells	Standard Deviation 0.00608276
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0175000 percentage of CD4+ T cells	Standard Deviation 0.00070711
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0016115 percentage of CD4+ T cells	Standard Deviation 0.00102601
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0595000 percentage of CD4+ T cells	Standard Deviation 0.01343503
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 15	0.0045367 percentage of CD4+ T cells	Standard Deviation 0.00785774
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.0052677 percentage of CD4+ T cells	Standard Deviation 0.00341188
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0500000 percentage of CD4+ T cells	Standard Deviation 0.07
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0050000 percentage of CD4+ T cells	Standard Deviation 0.00866025
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 105	0.0040567 percentage of CD4+ T cells	Standard Deviation 0.00418584
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0050000 percentage of CD4+ T cells	Standard Deviation 0.00707107
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.0016000 percentage of CD4+ T cells	Standard Deviation 0.00277128
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 15	0.0210000 percentage of CD4+ T cells	Standard Deviation 0.03637307
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 105	0.0016667 percentage of CD4+ T cells	Standard Deviation 0.00152753
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 15	0.0176667 percentage of CD4+ T cells	Standard Deviation 0.01078579
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 105	0.0063267 percentage of CD4+ T cells	Standard Deviation 0.01095811
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0009033 percentage of CD4+ T cells	Standard Deviation 0.00078932
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	FNg-, IL2+, TNFa-, DENV-1, prME, Day 105	0.0040000 percentage of CD4+ T cells	Standard Deviation 0.00608276
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	FNg-, IL2+, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0030000 percentage of CD4+ T cells	Standard Deviation 0.00519615
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 15	0.0376667 percentage of CD4+ T cells	Standard Deviation 0.01569501
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0700000 percentage of CD4+ T cells	Standard Deviation 0.10440307
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0350000 percentage of CD4+ T cells	Standard Deviation 0.0212132
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0596667 percentage of CD4+ T cells	Standard Deviation 0.06961561
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 105	0.0026967 percentage of CD4+ T cells	Standard Deviation 0.00223813
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0003635 percentage of CD4+ T cells	Standard Deviation 0.00051407
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0055467 percentage of CD4+ T cells	Standard Deviation 0.00026764
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	FNg-, IL2+, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0205000 percentage of CD4+ T cells	Standard Deviation 0.0106066
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0020875 percentage of CD4+ T cells	Standard Deviation 0.00290267
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0370000 percentage of CD4+ T cells	Standard Deviation 0.03517101
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 15	0.0010800 percentage of CD4+ T cells	Standard Deviation 0.00175923
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 15	0.0016633 percentage of CD4+ T cells	Standard Deviation 0.00144057
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0042860 percentage of CD4+ T cells	Standard Deviation 0.00392989
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 105	0.0021767 percentage of CD4+ T cells	Standard Deviation 0.00293742
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 105	0.0043267 percentage of CD4+ T cells	Standard Deviation 0.00749401
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0099800 percentage of CD4+ T cells	Standard Deviation 0.01728587
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0039667 percentage of CD4+ T cells	Standard Deviation 0.00308171
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 105	0.0733333 percentage of CD4+ T cells	Standard Deviation 0.08736895
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0193333 percentage of CD4+ T cells	Standard Deviation 0.03348632
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0032340 percentage of CD4+ T cells	Standard Deviation 0.00314804
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0013000 percentage of CD4+ T cells	Standard Deviation 0.00162631
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0485000 percentage of CD4+ T cells	Standard Deviation 0.03181981
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 15	0.0396233 percentage of CD4+ T cells	Standard Deviation 0.02896264
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 105	0.0004667 percentage of CD4+ T cells	Standard Deviation 0.00080829
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0466667 percentage of CD4+ T cells	Standard Deviation 0.08082904
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 105	0.0005800 percentage of CD4+ T cells	Standard Deviation 0.00100459
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0150933 percentage of CD4+ T cells	Standard Deviation 0.00694661
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 15	0.0346667 percentage of CD4+ T cells	Standard Deviation 0.01833939
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0009135 percentage of CD4+ T cells	Standard Deviation 0.00126784
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 105	0.0109133 percentage of CD4+ T cells	Standard Deviation 0.00335871
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0018300 percentage of CD4+ T cells	Standard Deviation 0.00189834
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0039300 percentage of CD4+ T cells	Standard Deviation 0.00413312
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0021353 percentage of CD4+ T cells	Standard Deviation 0.00311525
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0063440 percentage of CD4+ T cells	Standard Deviation 0.00014991
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0043133 percentage of CD4+ T cells	Standard Deviation 0.00447823
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 15	0.0018700 percentage of CD4+ T cells	Standard Deviation 0.00323894
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 15	0.0158833 percentage of CD4+ T cells	Standard Deviation 0.01526418
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 15	0.0500000 percentage of CD4+ T cells	Standard Deviation 0.0781025
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0008220 percentage of CD4+ T cells	Standard Deviation 0.00084058
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0049393 percentage of CD4+ T cells	Standard Deviation 0.00441403
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 15	0.0156567 percentage of CD4+ T cells	Standard Deviation 0.01987399
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0140527 percentage of CD4+ T cells	Standard Deviation 0.01124558
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 105	0.0003333 percentage of CD4+ T cells	Standard Deviation 0.00057735
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0037833 percentage of CD4+ T cells	Standard Deviation 0.00366041
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0005700 percentage of CD4+ T cells	Standard Deviation 0.00098727
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.0117927 percentage of CD4+ T cells	Standard Deviation 0.00809815
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0012250 percentage of CD4+ T cells	Standard Deviation 0.00173241
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0055893 percentage of CD4+ T cells	Standard Deviation 0.00486565
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 105	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0015433 percentage of CD4+ T cells	Standard Deviation 0.00167828
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 15	0.0002150 percentage of CD4+ T cells	Standard Deviation 0.00037239
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0040000 percentage of CD4+ T cells	Standard Deviation 0.0069282
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 105	0.0010267 percentage of CD4+ T cells	Standard Deviation 0.00177824
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0113333 percentage of CD4+ T cells	Standard Deviation 0.01001665
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0046400 percentage of CD4+ T cells	Standard Deviation 0.0064317
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0009263 percentage of CD4+ T cells	Standard Deviation 0.00157941
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0038167 percentage of CD4+ T cells	Standard Deviation 0.00109573
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 105	0.0074700 percentage of CD4+ T cells	Standard Deviation 0.0086852
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0004867 percentage of CD4+ T cells	Standard Deviation 0.00084293
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0570000 percentage of CD4+ T cells	Standard Deviation 0.06408588
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0060967 percentage of CD4+ T cells	Standard Deviation 0.00653743
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0120000 percentage of CD4+ T cells	Standard Deviation 0.01697056
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0012700 percentage of CD4+ T cells	Standard Deviation 0.00179605
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.0057620 percentage of CD4+ T cells	Standard Deviation 0.00888965
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0074967 percentage of CD4+ T cells	Standard Deviation 0.00705266
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 15	0.0032200 percentage of CD4+ T cells	Standard Deviation 0.0040449
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 15	0.0061433 percentage of CD4+ T cells	Standard Deviation 0.00488514
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0030600 percentage of CD4+ T cells	Standard Deviation 0.00204404
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0002013 percentage of CD4+ T cells	Standard Deviation 0.00034872
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 15	0.0182233 percentage of CD4+ T cells	Standard Deviation 0.01991388
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0007633 percentage of CD4+ T cells	Standard Deviation 0.00085043
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.1056667 percentage of CD4+ T cells	Standard Deviation 0.10390541
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0194627 percentage of CD4+ T cells	Standard Deviation 0.01535958
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 105	0.0043500 percentage of CD4+ T cells	Standard Deviation 0.00284628
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0075220 percentage of CD4+ T cells	Standard Deviation 0.00887617
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0142633 percentage of CD4+ T cells	Standard Deviation 0.00845533
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 105	0.0012300 percentage of CD4+ T cells	Standard Deviation 0.00111665
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 105	0.0009600 percentage of CD4+ T cells	Standard Deviation 0.00088386
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 15	0.0004667 percentage of CD4+ T cells	Standard Deviation 0.00080829
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0049000 percentage of CD4+ T cells	Standard Deviation 0.00652393
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 105	0.0025567 percentage of CD4+ T cells	Standard Deviation 0.00157912
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0005833 percentage of CD4+ T cells	Standard Deviation 0.00101036
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0017500 percentage of CD4+ T cells	Standard Deviation 0.00303109
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 105	0.0069667 percentage of CD4+ T cells	Standard Deviation 0.0107357
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0008543 percentage of CD4+ T cells	Standard Deviation 0.00093306
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0010277 percentage of CD4+ T cells	Standard Deviation 0.00133012
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 105	0.0015733 percentage of CD4+ T cells	Standard Deviation 0.00166677
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0010335 percentage of CD4+ T cells	Standard Deviation 0.00146159
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 15	0.0032367 percentage of CD4+ T cells	Standard Deviation 0.00336125
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0133333 percentage of CD4+ T cells	Standard Deviation 0.02309401
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0016035 percentage of CD4+ T cells	Standard Deviation 0.00145169
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0031500 percentage of CD4+ T cells	Standard Deviation 0.00279426
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 105	0.0500000 percentage of CD4+ T cells	Standard Deviation 0.07
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 15	0.0034600 percentage of CD4+ T cells	Standard Deviation 0.00072547
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0000010 percentage of CD4+ T cells	Standard Deviation 0.00000141
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 105	0.0700000 percentage of CD4+ T cells	Standard Deviation 0.12124356
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0009560 percentage of CD4+ T cells	Standard Deviation 0.00076228
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0024485 percentage of CD4+ T cells	Standard Deviation 0.00167089
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.0034733 percentage of CD4+ T cells	Standard Deviation 0.00388177
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0015343 percentage of CD4+ T cells	Standard Deviation 0.00028065
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0010335 percentage of CD4+ T cells	Standard Deviation 0.00146159
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 105	0.0069933 percentage of CD4+ T cells	Standard Deviation 0.00607619
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 15	0.0132000 percentage of CD4+ T cells	Standard Deviation 0.00930161
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 15	0.0473333 percentage of CD4+ T cells	Standard Deviation 0.03165965
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 15	0.0026567 percentage of CD4+ T cells	Standard Deviation 0.00243097
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0346667 percentage of CD4+ T cells	Standard Deviation 0.03500476
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0190567 percentage of CD4+ T cells	Standard Deviation 0.01080034
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 105	0.0076500 percentage of CD4+ T cells	Standard Deviation 0.0052643
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0021460 percentage of CD4+ T cells	Standard Deviation 0.00082412
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0000010 percentage of CD4+ T cells	Standard Deviation 0.00000141
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 15	0.0097900 percentage of CD4+ T cells	Standard Deviation 0.01084422
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0028800 percentage of CD4+ T cells	Standard Deviation 0.00258519
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0170000 percentage of CD4+ T cells	Standard Deviation 0.02404163
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0018733 percentage of CD4+ T cells	Standard Deviation 0.0003876
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 105	0.0013200 percentage of CD4+ T cells	Standard Deviation 0.00117235
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0073333 percentage of CD4+ T cells	Standard Deviation 0.01021437
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0029385 percentage of CD4+ T cells	Standard Deviation 0.00085065
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 15	0.1576667 percentage of CD4+ T cells	Standard Deviation 0.05173329
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0003085 percentage of CD4+ T cells	Standard Deviation 0.00043628
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 105	0.0022467 percentage of CD4+ T cells	Standard Deviation 0.00267792
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 105	0.0016133 percentage of CD4+ T cells	Standard Deviation 0.00163026
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0006033 percentage of CD4+ T cells	Standard Deviation 0.001045
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 15	0.1443333 percentage of CD4+ T cells	Standard Deviation 0.09152231
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0032910 percentage of CD4+ T cells	Standard Deviation 0.00127837
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0022325 percentage of CD4+ T cells	Standard Deviation 0.00194384
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 15	0.0520867 percentage of CD4+ T cells	Standard Deviation 0.05471529
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0070000 percentage of CD4+ T cells	Standard Deviation 0.01212436
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0034967 percentage of CD4+ T cells	Standard Deviation 0.0030381
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0000833 percentage of CD4+ T cells	Standard Deviation 0.00014434
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0003185 percentage of CD4+ T cells	Standard Deviation 0.00045043
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0107867 percentage of CD4+ T cells	Standard Deviation 0.01190998
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 105	0.0014633 percentage of CD4+ T cells	Standard Deviation 0.00168138
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0051633 percentage of CD4+ T cells	Standard Deviation 0.0069
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 105	0.0098533 percentage of CD4+ T cells	Standard Deviation 0.00613096
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 105	0.0038967 percentage of CD4+ T cells	Standard Deviation 0.004004
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 15	0.0029133 percentage of CD4+ T cells	Standard Deviation 0.00493389
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0126110 percentage of CD4+ T cells	Standard Deviation 0.01695829
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 15	0.0065773 percentage of CD4+ T cells	Standard Deviation 0.0061934
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0021167 percentage of CD4+ T cells	Standard Deviation 0.00171704
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0004275 percentage of CD4+ T cells	Standard Deviation 0.00058336
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 15	0.0096033 percentage of CD4+ T cells	Standard Deviation 0.00523661
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0021233 percentage of CD4+ T cells	Standard Deviation 0.00266215
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0050000 percentage of CD4+ T cells	Standard Deviation 0.00866025
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0057660 percentage of CD4+ T cells	Standard Deviation 0.0037094
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0006533 percentage of CD4+ T cells	Standard Deviation 0.00106308
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 15	0.0222033 percentage of CD4+ T cells	Standard Deviation 0.03371578
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0020620 percentage of CD4+ T cells	Standard Deviation 0.00178653
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0145000 percentage of CD4+ T cells	Standard Deviation 0.0205061
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 105	0.0036733 percentage of CD4+ T cells	Standard Deviation 0.00290569
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0003085 percentage of CD4+ T cells	Standard Deviation 0.00043628
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 105	0.1556667 percentage of CD4+ T cells	Standard Deviation 0.14424401
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0010100 percentage of CD4+ T cells	Standard Deviation 0.00156272
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 105	0.0000000 percentage of CD4+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0049800 percentage of CD4+ T cells	Standard Deviation 0.00862561
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0029585 percentage of CD4+ T cells	Standard Deviation 0.00170908
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0062267 percentage of CD4+ T cells	Standard Deviation 0.00469696
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0480000 percentage of CD4+ T cells	Standard Deviation 0.02828427
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 15	0.0026533 percentage of CD4+ T cells	Standard Deviation 0.00089891
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 15	0.0010083 percentage of CD4+ T cells	Standard Deviation 0.0012309
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0060000 percentage of CD4+ T cells	Standard Deviation 0.0103923
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0014793 percentage of CD4+ T cells	Standard Deviation 0.00041333
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0540000 percentage of CD4+ T cells	Standard Deviation 0.03751
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0043333 percentage of CD4+ T cells	Standard Deviation 0.00585947
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0013687 percentage of CD4+ T cells	Standard Deviation 0.00170601
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 120 (Month 4)	0.1313333 percentage of CD4+ T cells	Standard Deviation 0.16341767
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0176733 percentage of CD4+ T cells	Standard Deviation 0.02887941
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 105	0.0005433 percentage of CD4+ T cells	Standard Deviation 0.00094108
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0018260 percentage of CD4+ T cells	Standard Deviation 0.00126872
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0134067 percentage of CD4+ T cells	Standard Deviation 0.02049576
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0004800 percentage of CD4+ T cells	Standard Deviation 0.00083138

Secondary

Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)

Phenotype characterization of cellular immune response was performed in a subset of participants with IFN- γ ELISPOT responses \>50 SFC/10\^6 cells and availability of sufficient cells. Markers included CD4, CD8, IFN-γ, tumor necrosis factor-alpha (TNF-α) and interleukin-2 (IL-2). The peptide pools included C, NS1, NS2/4, NS3, NS5 for DENV-2 and prME for DENV-1, DENV-2, DENV-3 and DENV-4.

Time frame: Days 15, 30 (Month 1), 90 (Month 3), 105, 120 (Month 4), and 360 (Month 12)

Population: ICS Subset included participants from PPS (all participants in the FAS who had no major protocol violations) who had IFN-γ ELISPOT responses \>50 SFC/10\^6 PBMCs and availability of sufficient cells for analysis. Number analyzed is the number of participants with data available for analysis for the specified timepoint.

Arm	Measure	Group	Value (MEAN)	Dispersion
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0037833 percentage of CD8+ T cells	Standard Deviation 0.01041435
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.1106415 percentage of CD8+ T cells	Standard Deviation 0.28502664
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 15	0.0559643 percentage of CD8+ T cells	Standard Deviation 0.06460712
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0074013 percentage of CD8+ T cells	Standard Deviation 0.01825981
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0044441 percentage of CD8+ T cells	Standard Deviation 0.00551617
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.1805500 percentage of CD8+ T cells	Standard Deviation 0.26929623
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 15	0.0004090 percentage of CD8+ T cells	Standard Deviation 0.00081029
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0034878 percentage of CD8+ T cells	Standard Deviation 0.00469261
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 105	0.1034720 percentage of CD8+ T cells	Standard Deviation 0.10489211
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0004844 percentage of CD8+ T cells	Standard Deviation 0.00107834
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0295267 percentage of CD8+ T cells	Standard Deviation 0.04211372
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.1737812 percentage of CD8+ T cells	Standard Deviation 0.29061637
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0003021 percentage of CD8+ T cells	Standard Deviation 0.00109132
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 105	0.0078000 percentage of CD8+ T cells	Standard Deviation 0.01744133
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 105	0.0113983 percentage of CD8+ T cells	Standard Deviation 0.01184397
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.1922011 percentage of CD8+ T cells	Standard Deviation 0.3257894
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 15	0.0509037 percentage of CD8+ T cells	Standard Deviation 0.10340779
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0011589 percentage of CD8+ T cells	Standard Deviation 0.00257448
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0076250 percentage of CD8+ T cells	Standard Deviation 0.01245492
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.1513091 percentage of CD8+ T cells	Standard Deviation 0.21942879
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 15	0.0028214 percentage of CD8+ T cells	Standard Deviation 0.00421069
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0023636 percentage of CD8+ T cells	Standard Deviation 0.0027303
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0899900 percentage of CD8+ T cells	Standard Deviation 0.1284017
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0046852 percentage of CD8+ T cells	Standard Deviation 0.0062211
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 105	0.0012082 percentage of CD8+ T cells	Standard Deviation 0.00231967
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 105	0.0423867 percentage of CD8+ T cells	Standard Deviation 0.04081753
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0014295 percentage of CD8+ T cells	Standard Deviation 0.00279758
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0159263 percentage of CD8+ T cells	Standard Deviation 0.01687248
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0778682 percentage of CD8+ T cells	Standard Deviation 0.14369053
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 105	0.0010000 percentage of CD8+ T cells	Standard Deviation 0.002
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0059764 percentage of CD8+ T cells	Standard Deviation 0.00713827
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.1050295 percentage of CD8+ T cells	Standard Deviation 0.20473645
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0030000 percentage of CD8+ T cells	Standard Deviation 0.00441073
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0023789 percentage of CD8+ T cells	Standard Deviation 0.00539609
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 15	0.0127219 percentage of CD8+ T cells	Standard Deviation 0.01763276
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0044918 percentage of CD8+ T cells	Standard Deviation 0.00731866
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0007944 percentage of CD8+ T cells	Standard Deviation 0.00238333
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 15	0.0058100 percentage of CD8+ T cells	Standard Deviation 0.00997299
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0652592 percentage of CD8+ T cells	Standard Deviation 0.1148535
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0027273 percentage of CD8+ T cells	Standard Deviation 0.00904534
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0049679 percentage of CD8+ T cells	Standard Deviation 0.00700541
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0076840 percentage of CD8+ T cells	Standard Deviation 0.0165777
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 105	0.0001374 percentage of CD8+ T cells	Standard Deviation 0.00030724
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0030861 percentage of CD8+ T cells	Standard Deviation 0.00437015
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0032727 percentage of CD8+ T cells	Standard Deviation 0.0039266
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0020895 percentage of CD8+ T cells	Standard Deviation 0.00598185
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 105	0.0061340 percentage of CD8+ T cells	Standard Deviation 0.00559455
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0037375 percentage of CD8+ T cells	Standard Deviation 0.01220309
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0040000 percentage of CD8+ T cells	Standard Deviation 0.00418994
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 15	0.0033314 percentage of CD8+ T cells	Standard Deviation 0.01348231
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0084900 percentage of CD8+ T cells	Standard Deviation 0.00839871
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 15	0.0030476 percentage of CD8+ T cells	Standard Deviation 0.01094264
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0076211 percentage of CD8+ T cells	Standard Deviation 0.0127181
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0003888 percentage of CD8+ T cells	Standard Deviation 0.00109955
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0016822 percentage of CD8+ T cells	Standard Deviation 0.00344548
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0010313 percentage of CD8+ T cells	Standard Deviation 0.00198803
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0082836 percentage of CD8+ T cells	Standard Deviation 0.01892632
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 15	0.0058029 percentage of CD8+ T cells	Standard Deviation 0.015533
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 105	0.0032000 percentage of CD8+ T cells	Standard Deviation 0.00715542
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0016900 percentage of CD8+ T cells	Standard Deviation 0.00330848
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0866393 percentage of CD8+ T cells	Standard Deviation 0.13212126
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0009306 percentage of CD8+ T cells	Standard Deviation 0.00314498
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 15	0.0024200 percentage of CD8+ T cells	Standard Deviation 0.00800006
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0237878 percentage of CD8+ T cells	Standard Deviation 0.03150909
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0004506 percentage of CD8+ T cells	Standard Deviation 0.00101312
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0011563 percentage of CD8+ T cells	Standard Deviation 0.00285872
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0103476 percentage of CD8+ T cells	Standard Deviation 0.01374186
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 15	0.0004213 percentage of CD8+ T cells	Standard Deviation 0.00110644
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 105	0.0014160 percentage of CD8+ T cells	Standard Deviation 0.00316627
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 15	0.0148095 percentage of CD8+ T cells	Standard Deviation 0.02511227
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0123264 percentage of CD8+ T cells	Standard Deviation 0.024866
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0039800 percentage of CD8+ T cells	Standard Deviation 0.01170301
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0141552 percentage of CD8+ T cells	Standard Deviation 0.02722292
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 15	0.0059200 percentage of CD8+ T cells	Standard Deviation 0.01028071
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.0185150 percentage of CD8+ T cells	Standard Deviation 0.03662069
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 15	0.0144803 percentage of CD8+ T cells	Standard Deviation 0.0273044
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0141164 percentage of CD8+ T cells	Standard Deviation 0.0228246
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 105	0.0066317 percentage of CD8+ T cells	Standard Deviation 0.00614863
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0370610 percentage of CD8+ T cells	Standard Deviation 0.11025384
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 105	0.0141667 percentage of CD8+ T cells	Standard Deviation 0.02123598
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.0375398 percentage of CD8+ T cells	Standard Deviation 0.08260377
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0241643 percentage of CD8+ T cells	Standard Deviation 0.03587491
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 105	0.0439383 percentage of CD8+ T cells	Standard Deviation 0.0577916
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 15	0.0046910 percentage of CD8+ T cells	Standard Deviation 0.00688923
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0047727 percentage of CD8+ T cells	Standard Deviation 0.00882216
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0602155 percentage of CD8+ T cells	Standard Deviation 0.15407711
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0091942 percentage of CD8+ T cells	Standard Deviation 0.01593313
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 105	0.0045183 percentage of CD8+ T cells	Standard Deviation 0.00427166
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0112811 percentage of CD8+ T cells	Standard Deviation 0.01654078
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0327508 percentage of CD8+ T cells	Standard Deviation 0.05413463
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.0169390 percentage of CD8+ T cells	Standard Deviation 0.0307426
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 15	0.0159699 percentage of CD8+ T cells	Standard Deviation 0.04359877
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.1042408 percentage of CD8+ T cells	Standard Deviation 0.16997426
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.0233062 percentage of CD8+ T cells	Standard Deviation 0.0400272
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0707734 percentage of CD8+ T cells	Standard Deviation 0.25211961
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 15	0.0054286 percentage of CD8+ T cells	Standard Deviation 0.00981311
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 15	0.0041307 percentage of CD8+ T cells	Standard Deviation 0.00810849
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0288527 percentage of CD8+ T cells	Standard Deviation 0.08127031
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0594618 percentage of CD8+ T cells	Standard Deviation 0.09358403
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0022100 percentage of CD8+ T cells	Standard Deviation 0.00348368
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 105	0.0070820 percentage of CD8+ T cells	Standard Deviation 0.01452614
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 105	0.0238000 percentage of CD8+ T cells	Standard Deviation 0.02763512
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0560967 percentage of CD8+ T cells	Standard Deviation 0.15418829
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0198388 percentage of CD8+ T cells	Standard Deviation 0.04371084
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0050200 percentage of CD8+ T cells	Standard Deviation 0.00831467
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0019478 percentage of CD8+ T cells	Standard Deviation 0.00186916
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 15	0.0188947 percentage of CD8+ T cells	Standard Deviation 0.02597596
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 105	0.0031980 percentage of CD8+ T cells	Standard Deviation 0.00289504
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 15	0.0003281 percentage of CD8+ T cells	Standard Deviation 0.00087119
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0149633 percentage of CD8+ T cells	Standard Deviation 0.02271217
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0014660 percentage of CD8+ T cells	Standard Deviation 0.00368403
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0085812 percentage of CD8+ T cells	Standard Deviation 0.01180887
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0018853 percentage of CD8+ T cells	Standard Deviation 0.00779198
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0218395 percentage of CD8+ T cells	Standard Deviation 0.03032141
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0106266 percentage of CD8+ T cells	Standard Deviation 0.01670632
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 105	0.0008120 percentage of CD8+ T cells	Standard Deviation 0.00181569
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0624582 percentage of CD8+ T cells	Standard Deviation 0.07686613
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0165321 percentage of CD8+ T cells	Standard Deviation 0.03349865
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0004069 percentage of CD8+ T cells	Standard Deviation 0.00077459
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 15	0.0021547 percentage of CD8+ T cells	Standard Deviation 0.00463731
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0017656 percentage of CD8+ T cells	Standard Deviation 0.00266025
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 15	0.0103350 percentage of CD8+ T cells	Standard Deviation 0.01602034
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0012100 percentage of CD8+ T cells	Standard Deviation 0.00158071
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 15	0.0030481 percentage of CD8+ T cells	Standard Deviation 0.00520443
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0217506 percentage of CD8+ T cells	Standard Deviation 0.03474512
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0041225 percentage of CD8+ T cells	Standard Deviation 0.00963517
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0029060 percentage of CD8+ T cells	Standard Deviation 0.00436453
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0150073 percentage of CD8+ T cells	Standard Deviation 0.01487729
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 105	0.0010662 percentage of CD8+ T cells	Standard Deviation 0.00230033
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0040816 percentage of CD8+ T cells	Standard Deviation 0.00613449
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0063789 percentage of CD8+ T cells	Standard Deviation 0.00762607
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0036457 percentage of CD8+ T cells	Standard Deviation 0.01124294
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 105	0.0232000 percentage of CD8+ T cells	Standard Deviation 0.01003494
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0085133 percentage of CD8+ T cells	Standard Deviation 0.03027644
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0020000 percentage of CD8+ T cells	Standard Deviation 0.003
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 105	0.0066820 percentage of CD8+ T cells	Standard Deviation 0.00839444
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 15	0.0015550 percentage of CD8+ T cells	Standard Deviation 0.00250835
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0115435 percentage of CD8+ T cells	Standard Deviation 0.01646364
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0037368 percentage of CD8+ T cells	Standard Deviation 0.00647081
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0016022 percentage of CD8+ T cells	Standard Deviation 0.00296454
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0093311 percentage of CD8+ T cells	Standard Deviation 0.01492871
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0698280 percentage of CD8+ T cells	Standard Deviation 0.11664297
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0064197 percentage of CD8+ T cells	Standard Deviation 0.01469896
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 105	0.0246000 percentage of CD8+ T cells	Standard Deviation 0.0281567
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 105	0.0180160 percentage of CD8+ T cells	Standard Deviation 0.04024029
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 105	0.0000094 percentage of CD8+ T cells	Standard Deviation 0.00002102
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0250255 percentage of CD8+ T cells	Standard Deviation 0.03675944
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0042890 percentage of CD8+ T cells	Standard Deviation 0.00519741
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0056398 percentage of CD8+ T cells	Standard Deviation 0.01706862
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0386067 percentage of CD8+ T cells	Standard Deviation 0.03656897
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0789200 percentage of CD8+ T cells	Standard Deviation 0.08581529
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 15	0.0032181 percentage of CD8+ T cells	Standard Deviation 0.0108589
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 105	0.0006717 percentage of CD8+ T cells	Standard Deviation 0.00164524
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 15	0.0103743 percentage of CD8+ T cells	Standard Deviation 0.01256981
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0023250 percentage of CD8+ T cells	Standard Deviation 0.00398039
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0090928 percentage of CD8+ T cells	Standard Deviation 0.01602139
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 15	0.0039386 percentage of CD8+ T cells	Standard Deviation 0.00920362
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0042550 percentage of CD8+ T cells	Standard Deviation 0.00972955
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0115891 percentage of CD8+ T cells	Standard Deviation 0.01525538
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 15	0.0101905 percentage of CD8+ T cells	Standard Deviation 0.01632825
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0009700 percentage of CD8+ T cells	Standard Deviation 0.00213416
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 15	0.0115911 percentage of CD8+ T cells	Standard Deviation 0.02556364
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0027321 percentage of CD8+ T cells	Standard Deviation 0.00433336
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0009874 percentage of CD8+ T cells	Standard Deviation 0.00211314
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0331987 percentage of CD8+ T cells	Standard Deviation 0.06119374
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 105	0.0246240 percentage of CD8+ T cells	Standard Deviation 0.03733209
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.0020010 percentage of CD8+ T cells	Standard Deviation 0.0038593
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 15	0.0008767 percentage of CD8+ T cells	Standard Deviation 0.00230893
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0097230 percentage of CD8+ T cells	Standard Deviation 0.01765134
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0269048 percentage of CD8+ T cells	Standard Deviation 0.03805993
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0944508 percentage of CD8+ T cells	Standard Deviation 0.21411201
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 15	0.0188293 percentage of CD8+ T cells	Standard Deviation 0.02998412
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0598512 percentage of CD8+ T cells	Standard Deviation 0.09417635
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0002267 percentage of CD8+ T cells	Standard Deviation 0.00068
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0482255 percentage of CD8+ T cells	Standard Deviation 0.06448748
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.0043576 percentage of CD8+ T cells	Standard Deviation 0.00713583
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0510614 percentage of CD8+ T cells	Standard Deviation 0.06214111
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 15	0.0042606 percentage of CD8+ T cells	Standard Deviation 0.00562943
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 15	0.0020662 percentage of CD8+ T cells	Standard Deviation 0.00415237
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 105	0.0508333 percentage of CD8+ T cells	Standard Deviation 0.05468242
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0494400 percentage of CD8+ T cells	Standard Deviation 0.0552383
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0002582 percentage of CD8+ T cells	Standard Deviation 0.00058436
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0050373 percentage of CD8+ T cells	Standard Deviation 0.00755522
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0526782 percentage of CD8+ T cells	Standard Deviation 0.05324075
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0021729 percentage of CD8+ T cells	Standard Deviation 0.00454334
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.0011667 percentage of CD8+ T cells	Standard Deviation 0.00251661
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 15	0.0088638 percentage of CD8+ T cells	Standard Deviation 0.01482118
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0344576 percentage of CD8+ T cells	Standard Deviation 0.03851547
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0130950 percentage of CD8+ T cells	Standard Deviation 0.01958094
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 105	0.0010000 percentage of CD8+ T cells	Standard Deviation 0.00244949
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0603471 percentage of CD8+ T cells	Standard Deviation 0.11313845
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 105	0.0643333 percentage of CD8+ T cells	Standard Deviation 0.09686004
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 15	0.0003738 percentage of CD8+ T cells	Standard Deviation 0.00092592
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0471067 percentage of CD8+ T cells	Standard Deviation 0.06000386
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0018358 percentage of CD8+ T cells	Standard Deviation 0.00385801
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.0029057 percentage of CD8+ T cells	Standard Deviation 0.00488854
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0758600 percentage of CD8+ T cells	Standard Deviation 0.11250364
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 15	0.0031157 percentage of CD8+ T cells	Standard Deviation 0.00523026
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 105	0.0380000 percentage of CD8+ T cells	Standard Deviation 0.0525119
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.0146317 percentage of CD8+ T cells	Standard Deviation 0.02786861
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 105	0.0007740 percentage of CD8+ T cells	Standard Deviation 0.00154767
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0123363 percentage of CD8+ T cells	Standard Deviation 0.0151456
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0427178 percentage of CD8+ T cells	Standard Deviation 0.0762646
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0004906 percentage of CD8+ T cells	Standard Deviation 0.0009967
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0363138 percentage of CD8+ T cells	Standard Deviation 0.05384733
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.0233700 percentage of CD8+ T cells	Standard Deviation 0.04004137
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 15	0.0048171 percentage of CD8+ T cells	Standard Deviation 0.00860057
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0005805 percentage of CD8+ T cells	Standard Deviation 0.00114013
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0054275 percentage of CD8+ T cells	Standard Deviation 0.00814845
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0142545 percentage of CD8+ T cells	Standard Deviation 0.01922025
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 15	0.0008511 percentage of CD8+ T cells	Standard Deviation 0.00168955
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 105	0.0174000 percentage of CD8+ T cells	Standard Deviation 0.01399286
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 105	0.0202000 percentage of CD8+ T cells	Standard Deviation 0.02198181
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0005464 percentage of CD8+ T cells	Standard Deviation 0.00126041
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 15	0.0066860 percentage of CD8+ T cells	Standard Deviation 0.01511548
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0194350 percentage of CD8+ T cells	Standard Deviation 0.06157246
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0017572 percentage of CD8+ T cells	Standard Deviation 0.00350183
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0120563 percentage of CD8+ T cells	Standard Deviation 0.02306468
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0025821 percentage of CD8+ T cells	Standard Deviation 0.00448167
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.1934944 percentage of CD8+ T cells	Standard Deviation 0.22273972
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 105	0.0009780 percentage of CD8+ T cells	Standard Deviation 0.00177382
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.3096533 percentage of CD8+ T cells	Standard Deviation 0.30258266
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0002343 percentage of CD8+ T cells	Standard Deviation 0.00074914
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0114040 percentage of CD8+ T cells	Standard Deviation 0.01887834
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 15	0.0157619 percentage of CD8+ T cells	Standard Deviation 0.02615375
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0012376 percentage of CD8+ T cells	Standard Deviation 0.00387489
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0107505 percentage of CD8+ T cells	Standard Deviation 0.01922024
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 15	0.0003586 percentage of CD8+ T cells	Standard Deviation 0.00095429
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0042031 percentage of CD8+ T cells	Standard Deviation 0.01075305
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0005133 percentage of CD8+ T cells	Standard Deviation 0.00152134
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0090167 percentage of CD8+ T cells	Standard Deviation 0.0215953
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0001489 percentage of CD8+ T cells	Standard Deviation 0.00044667
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0105474 percentage of CD8+ T cells	Standard Deviation 0.02561865
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 105	0.0072940 percentage of CD8+ T cells	Standard Deviation 0.00965853
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 15	0.0184242 percentage of CD8+ T cells	Standard Deviation 0.02939174
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0340990 percentage of CD8+ T cells	Standard Deviation 0.08904184
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0591005 percentage of CD8+ T cells	Standard Deviation 0.11403676
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0106618 percentage of CD8+ T cells	Standard Deviation 0.01504292
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 15	0.0178773 percentage of CD8+ T cells	Standard Deviation 0.06036485
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0313922 percentage of CD8+ T cells	Standard Deviation 0.04328981
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.1276062 percentage of CD8+ T cells	Standard Deviation 0.23983604
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0023488 percentage of CD8+ T cells	Standard Deviation 0.00154967
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 105	0.0078900 percentage of CD8+ T cells	Standard Deviation 0.00938985
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0031775 percentage of CD8+ T cells	Standard Deviation 0.006638
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0976318 percentage of CD8+ T cells	Standard Deviation 0.16524353
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0235620 percentage of CD8+ T cells	Standard Deviation 0.03383365
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0476683 percentage of CD8+ T cells	Standard Deviation 0.19290073
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 15	0.0220818 percentage of CD8+ T cells	Standard Deviation 0.05553037
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0099805 percentage of CD8+ T cells	Standard Deviation 0.01591483
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0004426 percentage of CD8+ T cells	Standard Deviation 0.00153225
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 15	0.0090000 percentage of CD8+ T cells	Standard Deviation 0.01403916
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0057029 percentage of CD8+ T cells	Standard Deviation 0.01291375
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0067122 percentage of CD8+ T cells	Standard Deviation 0.00782834
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 15	0.0020544 percentage of CD8+ T cells	Standard Deviation 0.00530875
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 15	0.0470239 percentage of CD8+ T cells	Standard Deviation 0.06626524
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.1124982 percentage of CD8+ T cells	Standard Deviation 0.16603829
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0043447 percentage of CD8+ T cells	Standard Deviation 0.00780649
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 105	0.0052000 percentage of CD8+ T cells	Standard Deviation 0.00589067
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.2221475 percentage of CD8+ T cells	Standard Deviation 0.32806338
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0027273 percentage of CD8+ T cells	Standard Deviation 0.00405194
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.2820981 percentage of CD8+ T cells	Standard Deviation 0.37844969
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 15	0.0014671 percentage of CD8+ T cells	Standard Deviation 0.0026363
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.1878077 percentage of CD8+ T cells	Standard Deviation 0.16247089
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.4990933 percentage of CD8+ T cells	Standard Deviation 0.64014167
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0026483 percentage of CD8+ T cells	Standard Deviation 0.00397803
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 105	0.0077060 percentage of CD8+ T cells	Standard Deviation 0.00514342
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0857582 percentage of CD8+ T cells	Standard Deviation 0.08578152
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0008555 percentage of CD8+ T cells	Standard Deviation 0.00283722
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0039322 percentage of CD8+ T cells	Standard Deviation 0.0091671
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 105	0.2131617 percentage of CD8+ T cells	Standard Deviation 0.2629006
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0009323 percentage of CD8+ T cells	Standard Deviation 0.0020502
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0049365 percentage of CD8+ T cells	Standard Deviation 0.00709962
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.3655695 percentage of CD8+ T cells	Standard Deviation 0.32065242
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0003679 percentage of CD8+ T cells	Standard Deviation 0.00110265
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0614767 percentage of CD8+ T cells	Standard Deviation 0.11059188
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.2064808 percentage of CD8+ T cells	Standard Deviation 0.20421574
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.1580330 percentage of CD8+ T cells	Standard Deviation 0.28256426
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 15	0.0506306 percentage of CD8+ T cells	Standard Deviation 0.07605994
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 105	0.1067160 percentage of CD8+ T cells	Standard Deviation 0.18769742
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0138195 percentage of CD8+ T cells	Standard Deviation 0.01653836
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 105	0.1576200 percentage of CD8+ T cells	Standard Deviation 0.17541417
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.1645845 percentage of CD8+ T cells	Standard Deviation 0.33473334
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0082212 percentage of CD8+ T cells	Standard Deviation 0.01488787
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 105	0.0042000 percentage of CD8+ T cells	Standard Deviation 0.00939149
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0154140 percentage of CD8+ T cells	Standard Deviation 0.02895635
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 15	0.0031952 percentage of CD8+ T cells	Standard Deviation 0.00507926
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.3801521 percentage of CD8+ T cells	Standard Deviation 0.67068473
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0834539 percentage of CD8+ T cells	Standard Deviation 0.27160793
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 15	0.0444316 percentage of CD8+ T cells	Standard Deviation 0.07748289
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0003618 percentage of CD8+ T cells	Standard Deviation 0.00078989
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0296555 percentage of CD8+ T cells	Standard Deviation 0.03699595
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0605858 percentage of CD8+ T cells	Standard Deviation 0.09889217
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0005989 percentage of CD8+ T cells	Standard Deviation 0.0012275
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 105	0.0434533 percentage of CD8+ T cells	Standard Deviation 0.063151
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0012515 percentage of CD8+ T cells	Standard Deviation 0.00280308
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0016056 percentage of CD8+ T cells	Standard Deviation 0.00247607
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0588364 percentage of CD8+ T cells	Standard Deviation 0.17313721
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0542124 percentage of CD8+ T cells	Standard Deviation 0.1150339
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0068115 percentage of CD8+ T cells	Standard Deviation 0.0078267
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0006105 percentage of CD8+ T cells	Standard Deviation 0.00166994
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 105	0.0001760 percentage of CD8+ T cells	Standard Deviation 0.00039355
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 15	0.0122389 percentage of CD8+ T cells	Standard Deviation 0.01635494
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0308133 percentage of CD8+ T cells	Standard Deviation 0.07834697
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0124347 percentage of CD8+ T cells	Standard Deviation 0.01836407
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0512582 percentage of CD8+ T cells	Standard Deviation 0.13375503
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 105	0.0108580 percentage of CD8+ T cells	Standard Deviation 0.01167522
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0337200 percentage of CD8+ T cells	Standard Deviation 0.04946269
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0008947 percentage of CD8+ T cells	Standard Deviation 0.00141229
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 15	0.0056604 percentage of CD8+ T cells	Standard Deviation 0.01627332
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0006700 percentage of CD8+ T cells	Standard Deviation 0.00147478
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0304975 percentage of CD8+ T cells	Standard Deviation 0.07184977
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0047007 percentage of CD8+ T cells	Standard Deviation 0.01502896
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0004136 percentage of CD8+ T cells	Standard Deviation 0.00137188
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0400210 percentage of CD8+ T cells	Standard Deviation 0.12804631
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0014703 percentage of CD8+ T cells	Standard Deviation 0.00267161
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0011780 percentage of CD8+ T cells	Standard Deviation 0.00287673
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0127111 percentage of CD8+ T cells	Standard Deviation 0.01056931
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 15	0.0084024 percentage of CD8+ T cells	Standard Deviation 0.02103704
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0023900 percentage of CD8+ T cells	Standard Deviation 0.00325169
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0080456 percentage of CD8+ T cells	Standard Deviation 0.00651373
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0078913 percentage of CD8+ T cells	Standard Deviation 0.01390167
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 15	0.0004690 percentage of CD8+ T cells	Standard Deviation 0.00108044
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.0031300 percentage of CD8+ T cells	Standard Deviation 0.00536305
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0212825 percentage of CD8+ T cells	Standard Deviation 0.04543103
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0008031 percentage of CD8+ T cells	Standard Deviation 0.00199994
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 15	0.0006238 percentage of CD8+ T cells	Standard Deviation 0.00118351
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 105	0.0321340 percentage of CD8+ T cells	Standard Deviation 0.06596445
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0010852 percentage of CD8+ T cells	Standard Deviation 0.0017637
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 15	0.0001975 percentage of CD8+ T cells	Standard Deviation 0.00067344
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0365866 percentage of CD8+ T cells	Standard Deviation 0.13503691
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 105	0.0016667 percentage of CD8+ T cells	Standard Deviation 0.00265832
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0043176 percentage of CD8+ T cells	Standard Deviation 0.00745474
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0003138 percentage of CD8+ T cells	Standard Deviation 0.00073427
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 15	0.0173215 percentage of CD8+ T cells	Standard Deviation 0.02522769
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 15	0.0018039 percentage of CD8+ T cells	Standard Deviation 0.00272657
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0009045 percentage of CD8+ T cells	Standard Deviation 0.00166618
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0047733 percentage of CD8+ T cells	Standard Deviation 0.0036927
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.5487509 percentage of CD8+ T cells	Standard Deviation 0.61534681
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 15	0.0010010 percentage of CD8+ T cells	Standard Deviation 0.00144763
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.0040000 percentage of CD8+ T cells	Standard Deviation 0.0052915
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.6520608 percentage of CD8+ T cells	Standard Deviation 1.02666427
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0012721 percentage of CD8+ T cells	Standard Deviation 0.00302348
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0668900 percentage of CD8+ T cells	Standard Deviation 0.14991991
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 105	0.3420600 percentage of CD8+ T cells	Standard Deviation 0.3521604
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0018919 percentage of CD8+ T cells	Standard Deviation 0.00612723
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0015591 percentage of CD8+ T cells	Standard Deviation 0.00239132
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.4983025 percentage of CD8+ T cells	Standard Deviation 0.59609158
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 105	0.0000050 percentage of CD8+ T cells	Standard Deviation 0.00001225
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0062678 percentage of CD8+ T cells	Standard Deviation 0.01052641
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.4733376 percentage of CD8+ T cells	Standard Deviation 0.74274218
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0005142 percentage of CD8+ T cells	Standard Deviation 0.00121641
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 105	0.0047020 percentage of CD8+ T cells	Standard Deviation 0.00507315
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 15	0.0577929 percentage of CD8+ T cells	Standard Deviation 0.07400744
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0016991 percentage of CD8+ T cells	Standard Deviation 0.00376328
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 15	0.0152389 percentage of CD8+ T cells	Standard Deviation 0.04708044
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.3919327 percentage of CD8+ T cells	Standard Deviation 0.07020651
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 15	0.0003723 percentage of CD8+ T cells	Standard Deviation 0.00107549
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0582231 percentage of CD8+ T cells	Standard Deviation 0.09890918
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0434985 percentage of CD8+ T cells	Standard Deviation 0.10671828
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.4698942 percentage of CD8+ T cells	Standard Deviation 0.59554812
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0001547 percentage of CD8+ T cells	Standard Deviation 0.00044269
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0052506 percentage of CD8+ T cells	Standard Deviation 0.0058523
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 105	0.1848933 percentage of CD8+ T cells	Standard Deviation 0.10624645
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 105	0.0108000 percentage of CD8+ T cells	Standard Deviation 0.0181989
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0055525 percentage of CD8+ T cells	Standard Deviation 0.02087829
TDV: Flavivirus-naïve	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.3367906 percentage of CD8+ T cells	Standard Deviation 0.391997
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.1045000 percentage of CD8+ T cells	Standard Deviation 0.12091526
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 105	0.0013600 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0030000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 15	0.0025550 percentage of CD8+ T cells	Standard Deviation 0.00361332
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0088700 percentage of CD8+ T cells	Standard Deviation 0.01254407
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0022800 percentage of CD8+ T cells	Standard Deviation 0.00322441
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0034850 percentage of CD8+ T cells	Standard Deviation 0.00492853
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0030800 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 15	0.0258900 percentage of CD8+ T cells	Standard Deviation 0.03126826
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0672150 percentage of CD8+ T cells	Standard Deviation 0.0887914
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 105	0.0036900 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0516100 percentage of CD8+ T cells	Standard Deviation 0.06701958
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0430000 percentage of CD8+ T cells	Standard Deviation 0.06081118
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0012400 percentage of CD8+ T cells	Standard Deviation 0.00135765
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.0054650 percentage of CD8+ T cells	Standard Deviation 0.0017607
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.1272350 percentage of CD8+ T cells	Standard Deviation 0.17361593
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0840000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 105	0.0250000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 105	0.0027500 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0078650 percentage of CD8+ T cells	Standard Deviation 0.01112279
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0304150 percentage of CD8+ T cells	Standard Deviation 0.0400576
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.3366500 percentage of CD8+ T cells	Standard Deviation 0.37002898
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0172600 percentage of CD8+ T cells	Standard Deviation 0.01199253
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 15	0.0090000 percentage of CD8+ T cells	Standard Deviation 0.01272792
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0195000 percentage of CD8+ T cells	Standard Deviation 0.0106066
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 105	0.0090000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0020000 percentage of CD8+ T cells	Standard Deviation 0.00282843
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 15	0.0060000 percentage of CD8+ T cells	Standard Deviation 0.00848528
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0090000 percentage of CD8+ T cells	Standard Deviation 0.00848528
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0070000 percentage of CD8+ T cells	Standard Deviation 0.00989949
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 105	0.0270000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0385000 percentage of CD8+ T cells	Standard Deviation 0.01484924
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0030000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 15	0.1070000 percentage of CD8+ T cells	Standard Deviation 0.13293607
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0555000 percentage of CD8+ T cells	Standard Deviation 0.06010408
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0770000 percentage of CD8+ T cells	Standard Deviation 0.10889444
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 105	0.0150000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.1095000 percentage of CD8+ T cells	Standard Deviation 0.13930004
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0180000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 15	0.0415000 percentage of CD8+ T cells	Standard Deviation 0.02616295
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.3430000 percentage of CD8+ T cells	Standard Deviation 0.33234019
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.3680000 percentage of CD8+ T cells	Standard Deviation 0.5176021
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.5175000 percentage of CD8+ T cells	Standard Deviation 0.67952962
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0530000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0780000 percentage of CD8+ T cells	Standard Deviation 0.05656854
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 105	0.0410000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0940000 percentage of CD8+ T cells	Standard Deviation 0.11879394
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 105	0.0100000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0440000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 15	0.0110000 percentage of CD8+ T cells	Standard Deviation 0.00141421
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0130000 percentage of CD8+ T cells	Standard Deviation 0.00141421
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 105	0.0080000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0210900 percentage of CD8+ T cells	Standard Deviation 0.02391435
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0190000 percentage of CD8+ T cells	Standard Deviation 0.02687006
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0029900 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 15	0.0025100 percentage of CD8+ T cells	Standard Deviation 0.00083439
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 105	0.0027000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 105	0.0027000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0125800 percentage of CD8+ T cells	Standard Deviation 0.01190768
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0048250 percentage of CD8+ T cells	Standard Deviation 0.00682358
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0261500 percentage of CD8+ T cells	Standard Deviation 0.02807214
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 105	0.0081100 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0029200 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0014600 percentage of CD8+ T cells	Standard Deviation 0.00206475
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 105	0.0080000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0000750 percentage of CD8+ T cells	Standard Deviation 0.00010607
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0047450 percentage of CD8+ T cells	Standard Deviation 0.00671044
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0022150 percentage of CD8+ T cells	Standard Deviation 0.00313248
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0000450 percentage of CD8+ T cells	Standard Deviation 0.00006364
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0016550 percentage of CD8+ T cells	Standard Deviation 0.00234052
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0015450 percentage of CD8+ T cells	Standard Deviation 0.00218496
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0000400 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0065000 percentage of CD8+ T cells	Standard Deviation 0.00919239
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0000400 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0007600 percentage of CD8+ T cells	Standard Deviation 0.0010748
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 15	0.0020000 percentage of CD8+ T cells	Standard Deviation 0.00282843
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0040000 percentage of CD8+ T cells	Standard Deviation 0.00565685
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0010000 percentage of CD8+ T cells	Standard Deviation 0.00141421
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 15	0.0025000 percentage of CD8+ T cells	Standard Deviation 0.00353553
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0015000 percentage of CD8+ T cells	Standard Deviation 0.00212132
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0010000 percentage of CD8+ T cells	Standard Deviation 0.00141421
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0060000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0026650 percentage of CD8+ T cells	Standard Deviation 0.00376888
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 105	0.0013600 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0008700 percentage of CD8+ T cells	Standard Deviation 0.00123037
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 15	0.0025450 percentage of CD8+ T cells	Standard Deviation 0.00359917
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0332550 percentage of CD8+ T cells	Standard Deviation 0.03782314
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0205000 percentage of CD8+ T cells	Standard Deviation 0.02899138
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0198650 percentage of CD8+ T cells	Standard Deviation 0.02809335
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0031000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 15	0.0017000 percentage of CD8+ T cells	Standard Deviation 0.00240416
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0278700 percentage of CD8+ T cells	Standard Deviation 0.01820093
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0117600 percentage of CD8+ T cells	Standard Deviation 0.01066317
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 105	0.0040800 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0060000 percentage of CD8+ T cells	Standard Deviation 0.00848528
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 15	0.0008500 percentage of CD8+ T cells	Standard Deviation 0.00120208
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0070000 percentage of CD8+ T cells	Standard Deviation 0.00989949
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 105	0.0018800 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0085000 percentage of CD8+ T cells	Standard Deviation 0.01202082
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 105	0.0110000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 15	0.0195000 percentage of CD8+ T cells	Standard Deviation 0.01767767
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0235000 percentage of CD8+ T cells	Standard Deviation 0.01343503
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0250000 percentage of CD8+ T cells	Standard Deviation 0.03535534
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 105	0.0110000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0295000 percentage of CD8+ T cells	Standard Deviation 0.03323402
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0055000 percentage of CD8+ T cells	Standard Deviation 0.00777817
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 15	0.0034050 percentage of CD8+ T cells	Standard Deviation 0.0048154
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0025150 percentage of CD8+ T cells	Standard Deviation 0.00355675
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.1423700 percentage of CD8+ T cells	Standard Deviation 0.17729995
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0815250 percentage of CD8+ T cells	Standard Deviation 0.11098041
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 15	0.0054950 percentage of CD8+ T cells	Standard Deviation 0.00047376
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0699200 percentage of CD8+ T cells	Standard Deviation 0.09591196
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 105	0.0039700 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0062300 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0008200 percentage of CD8+ T cells	Standard Deviation 0.00115966
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0011350 percentage of CD8+ T cells	Standard Deviation 0.00160513
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0030800 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 15	0.0025350 percentage of CD8+ T cells	Standard Deviation 0.00091217
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.0185000 percentage of CD8+ T cells	Standard Deviation 0.00777817
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.0085000 percentage of CD8+ T cells	Standard Deviation 0.01202082
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.0055000 percentage of CD8+ T cells	Standard Deviation 0.00777817
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0089800 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.0105000 percentage of CD8+ T cells	Standard Deviation 0.01484924
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 105	0.0026400 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.0045000 percentage of CD8+ T cells	Standard Deviation 0.00636396
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0031200 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 15	0.0130000 percentage of CD8+ T cells	Standard Deviation 0.01838478
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0500000 percentage of CD8+ T cells	Standard Deviation 0.07071068
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0325000 percentage of CD8+ T cells	Standard Deviation 0.04596194
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 105	0.0013300 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0433650 percentage of CD8+ T cells	Standard Deviation 0.06132737
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 15	0.0475000 percentage of CD8+ T cells	Standard Deviation 0.06717514
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0861200 percentage of CD8+ T cells	Standard Deviation 0.11862423
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 105	0.0026600 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.1188100 percentage of CD8+ T cells	Standard Deviation 0.16393564
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0030800 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 15	0.3345000 percentage of CD8+ T cells	Standard Deviation 0.38961584
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 30 (Month 1)	1.7050000 percentage of CD8+ T cells	Standard Deviation 2.10010714
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 90 (Month 3)	1.3950000 percentage of CD8+ T cells	Standard Deviation 1.81726443
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 105	0.1200000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 120 (Month 4)	1.4208650 percentage of CD8+ T cells	Standard Deviation 1.91465424
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 15	0.1345000 percentage of CD8+ T cells	Standard Deviation 0.16334167
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.8520000 percentage of CD8+ T cells	Standard Deviation 1.15682669
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.8565000 percentage of CD8+ T cells	Standard Deviation 1.19288914
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.9169950 percentage of CD8+ T cells	Standard Deviation 1.28373115
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0370000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 15	0.0009250 percentage of CD8+ T cells	Standard Deviation 0.00130815
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0086150 percentage of CD8+ T cells	Standard Deviation 0.0033729
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0105000 percentage of CD8+ T cells	Standard Deviation 0.01484924
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0087300 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 15	0.0042950 percentage of CD8+ T cells	Standard Deviation 0.00607405
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0171950 percentage of CD8+ T cells	Standard Deviation 0.018109
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0080000 percentage of CD8+ T cells	Standard Deviation 0.01131371
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0030300 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 15	0.0070000 percentage of CD8+ T cells	Standard Deviation 0.00989949
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0071500 percentage of CD8+ T cells	Standard Deviation 0.01011163
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0070000 percentage of CD8+ T cells	Standard Deviation 0.00989949
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 15	0.0130000 percentage of CD8+ T cells	Standard Deviation 0.01838478
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0512350 percentage of CD8+ T cells	Standard Deviation 0.06293957
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0448850 percentage of CD8+ T cells	Standard Deviation 0.05715544
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0249450 percentage of CD8+ T cells	Standard Deviation 0.03119048
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0030800 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 15	0.1770000 percentage of CD8+ T cells	Standard Deviation 0.11737973
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.7938700 percentage of CD8+ T cells	Standard Deviation 0.68429552
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 105	0.0650000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.2475000 percentage of CD8+ T cells	Standard Deviation 0.27223611
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0630000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 15	0.0575000 percentage of CD8+ T cells	Standard Deviation 0.05727565
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.3928700 percentage of CD8+ T cells	Standard Deviation 0.50186197
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.1433750 percentage of CD8+ T cells	Standard Deviation 0.19081276
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 105	0.0092500 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0062300 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0010400 percentage of CD8+ T cells	Standard Deviation 0.00147078
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 105	0.0011900 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0062500 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 15	0.0035250 percentage of CD8+ T cells	Standard Deviation 0.0022981
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0061500 percentage of CD8+ T cells	Standard Deviation 0.00281428
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 105	0.0055000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0000400 percentage of CD8+ T cells	Standard Deviation 0.00005657
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0009350 percentage of CD8+ T cells	Standard Deviation 0.00132229
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 15	0.0008500 percentage of CD8+ T cells	Standard Deviation 0.00120208
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0023600 percentage of CD8+ T cells	Standard Deviation 0.00333754
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 15	0.0010000 percentage of CD8+ T cells	Standard Deviation 0.00141421
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.0075000 percentage of CD8+ T cells	Standard Deviation 0.0106066
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 15	0.0025000 percentage of CD8+ T cells	Standard Deviation 0.00353553
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.0035000 percentage of CD8+ T cells	Standard Deviation 0.00494975
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.0040000 percentage of CD8+ T cells	Standard Deviation 0.00565685
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 105	0.1040000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 15	0.0350000 percentage of CD8+ T cells	Standard Deviation 0.02262742
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0870000 percentage of CD8+ T cells	Standard Deviation 0.12303658
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0090000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 15	0.0230000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0285000 percentage of CD8+ T cells	Standard Deviation 0.00777817
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0065000 percentage of CD8+ T cells	Standard Deviation 0.00919239
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0165000 percentage of CD8+ T cells	Standard Deviation 0.02333452
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0350000 percentage of CD8+ T cells	Standard Deviation 0.03818377
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0080000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0000650 percentage of CD8+ T cells	Standard Deviation 0.00009192
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0008900 percentage of CD8+ T cells	Standard Deviation 0.00125865
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 15	0.0089250 percentage of CD8+ T cells	Standard Deviation 0.00717713
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0153650 percentage of CD8+ T cells	Standard Deviation 0.02172939
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0203700 percentage of CD8+ T cells	Standard Deviation 0.01466539
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0063250 percentage of CD8+ T cells	Standard Deviation 0.00279307
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 105	0.0052300 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0060000 percentage of CD8+ T cells	Standard Deviation 0.00848528
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 15	0.0015500 percentage of CD8+ T cells	Standard Deviation 0.00219203
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0011950 percentage of CD8+ T cells	Standard Deviation 0.00168999
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0014550 percentage of CD8+ T cells	Standard Deviation 0.00205768
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0040000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0065000 percentage of CD8+ T cells	Standard Deviation 0.00919239
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 15	0.0255000 percentage of CD8+ T cells	Standard Deviation 0.00494975
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0205000 percentage of CD8+ T cells	Standard Deviation 0.01343503
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0205000 percentage of CD8+ T cells	Standard Deviation 0.02899138
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 105	0.0070000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0440000 percentage of CD8+ T cells	Standard Deviation 0.0622254
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0050000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0020800 percentage of CD8+ T cells	Standard Deviation 0.00294156
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0016100 percentage of CD8+ T cells	Standard Deviation 0.00227688
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0008400 percentage of CD8+ T cells	Standard Deviation 0.00118794
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 15	0.0017750 percentage of CD8+ T cells	Standard Deviation 0.00019092
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 105	0.0150000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0162450 percentage of CD8+ T cells	Standard Deviation 0.01058539
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0058400 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 15	0.0036850 percentage of CD8+ T cells	Standard Deviation 0.00289207
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0046900 percentage of CD8+ T cells	Standard Deviation 0.00005657
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0037600 percentage of CD8+ T cells	Standard Deviation 0.00294156
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 15	0.0016350 percentage of CD8+ T cells	Standard Deviation 0.00231224
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0000350 percentage of CD8+ T cells	Standard Deviation 0.0000495
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 105	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 15	0.0060000 percentage of CD8+ T cells	Standard Deviation 0.00848528
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0050000 percentage of CD8+ T cells	Standard Deviation 0.00707107
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0060000 percentage of CD8+ T cells	Standard Deviation 0.00848528
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 15	0.0595000 percentage of CD8+ T cells	Standard Deviation 0.05868986
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0180000 percentage of CD8+ T cells	Standard Deviation 0.02545584
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0125000 percentage of CD8+ T cells	Standard Deviation 0.01767767
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 105	0.0240000 percentage of CD8+ T cells	—
TDV: DENV Immune: DENV-1 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0300000 percentage of CD8+ T cells	Standard Deviation 0.03535534
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0000467 percentage of CD8+ T cells	Standard Deviation 0.00008083
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 105	0.0825367 percentage of CD8+ T cells	Standard Deviation 0.07078845
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0043667 percentage of CD8+ T cells	Standard Deviation 0.00583981
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.1260100 percentage of CD8+ T cells	Standard Deviation 0.08686409
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0070000 percentage of CD8+ T cells	Standard Deviation 0.00848528
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0216435 percentage of CD8+ T cells	Standard Deviation 0.00898945
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0113500 percentage of CD8+ T cells	Standard Deviation 0.01026974
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0180433 percentage of CD8+ T cells	Standard Deviation 0.02775222
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 15	0.0011667 percentage of CD8+ T cells	Standard Deviation 0.00202073
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 105	0.0007067 percentage of CD8+ T cells	Standard Deviation 0.00122398
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 105	0.0020467 percentage of CD8+ T cells	Standard Deviation 0.00354493
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0041833 percentage of CD8+ T cells	Standard Deviation 0.00218836
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.0066667 percentage of CD8+ T cells	Standard Deviation 0.01154701
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0013533 percentage of CD8+ T cells	Standard Deviation 0.00117309
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0028333 percentage of CD8+ T cells	Standard Deviation 0.00490748
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0010000 percentage of CD8+ T cells	Standard Deviation 0.00173205
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 105	0.0021467 percentage of CD8+ T cells	Standard Deviation 0.00199362
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS3, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0072167 percentage of CD8+ T cells	Standard Deviation 0.00913589
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0020933 percentage of CD8+ T cells	Standard Deviation 0.0031369
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0102150 percentage of CD8+ T cells	Standard Deviation 0.00596091
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 105	0.0053333 percentage of CD8+ T cells	Standard Deviation 0.00404145
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0025400 percentage of CD8+ T cells	Standard Deviation 0.0035921
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0035633 percentage of CD8+ T cells	Standard Deviation 0.0046325
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0020187 percentage of CD8+ T cells	Standard Deviation 0.00116433
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 15	0.0026897 percentage of CD8+ T cells	Standard Deviation 0.00335374
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0008833 percentage of CD8+ T cells	Standard Deviation 0.00152998
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0007200 percentage of CD8+ T cells	Standard Deviation 0.00101823
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0093150 percentage of CD8+ T cells	Standard Deviation 0.01317661
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.0023333 percentage of CD8+ T cells	Standard Deviation 0.00404145
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0027633 percentage of CD8+ T cells	Standard Deviation 0.00478623
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0293333 percentage of CD8+ T cells	Standard Deviation 0.05080682
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 105	0.0049600 percentage of CD8+ T cells	Standard Deviation 0.00751799
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0330000 percentage of CD8+ T cells	Standard Deviation 0.02868798
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0045967 percentage of CD8+ T cells	Standard Deviation 0.00557157
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0733333 percentage of CD8+ T cells	Standard Deviation 0.09451631
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0038600 percentage of CD8+ T cells	Standard Deviation 0.00397394
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0026885 percentage of CD8+ T cells	Standard Deviation 0.00176989
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 105	0.0076667 percentage of CD8+ T cells	Standard Deviation 0.00929157
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 15	0.0064300 percentage of CD8+ T cells	Standard Deviation 0.00844954
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 15	0.0557333 percentage of CD8+ T cells	Standard Deviation 0.06982874
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0969917 percentage of CD8+ T cells	Standard Deviation 0.10487019
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0047150 percentage of CD8+ T cells	Standard Deviation 0.00666802
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0118367 percentage of CD8+ T cells	Standard Deviation 0.01821354
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0521167 percentage of CD8+ T cells	Standard Deviation 0.0764146
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 105	0.0259533 percentage of CD8+ T cells	Standard Deviation 0.0327605
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 105	0.0410800 percentage of CD8+ T cells	Standard Deviation 0.06836592
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0004985 percentage of CD8+ T cells	Standard Deviation 0.00070499
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0032750 percentage of CD8+ T cells	Standard Deviation 0.00269408
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 15	0.0010000 percentage of CD8+ T cells	Standard Deviation 0.00173205
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0023900 percentage of CD8+ T cells	Standard Deviation 0.00272666
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0004017 percentage of CD8+ T cells	Standard Deviation 0.00055503
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0101350 percentage of CD8+ T cells	Standard Deviation 0.00905302
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 105	0.0012633 percentage of CD8+ T cells	Standard Deviation 0.00114718
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0257167 percentage of CD8+ T cells	Standard Deviation 0.01956887
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0050000 percentage of CD8+ T cells	Standard Deviation 0.00556776
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 105	0.0320700 percentage of CD8+ T cells	Standard Deviation 0.03599368
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 105	0.0006200 percentage of CD8+ T cells	Standard Deviation 0.00107387
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0141700 percentage of CD8+ T cells	Standard Deviation 0.01698637
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0097150 percentage of CD8+ T cells	Standard Deviation 0.01373908
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0240000 percentage of CD8+ T cells	Standard Deviation 0.03394113
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 105	0.0004167 percentage of CD8+ T cells	Standard Deviation 0.00072169
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 15	0.1204000 percentage of CD8+ T cells	Standard Deviation 0.08449249
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0009700 percentage of CD8+ T cells	Standard Deviation 0.00149362
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 15	0.0056667 percentage of CD8+ T cells	Standard Deviation 0.00550757
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 105	0.0487367 percentage of CD8+ T cells	Standard Deviation 0.03451214
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.0923333 percentage of CD8+ T cells	Standard Deviation 0.09666609
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.0493700 percentage of CD8+ T cells	Standard Deviation 0.03374277
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.0477333 percentage of CD8+ T cells	Standard Deviation 0.07132611
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0191600 percentage of CD8+ T cells	Standard Deviation 0.01674429
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.0370000 percentage of CD8+ T cells	Standard Deviation 0.0523259
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 15	0.0524000 percentage of CD8+ T cells	Standard Deviation 0.01247678
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0046667 percentage of CD8+ T cells	Standard Deviation 0.00568624
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.1050550 percentage of CD8+ T cells	Standard Deviation 0.03026614
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0150000 percentage of CD8+ T cells	Standard Deviation 0.0212132
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.1697217 percentage of CD8+ T cells	Standard Deviation 0.15709417
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.0326667 percentage of CD8+ T cells	Standard Deviation 0.01106044
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 360 (Month 12)	0.0050000 percentage of CD8+ T cells	Standard Deviation 0.00565685
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 105	0.0218933 percentage of CD8+ T cells	Standard Deviation 0.02273292
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 105	0.0050000 percentage of CD8+ T cells	Standard Deviation 0.006245
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 15	0.0025900 percentage of CD8+ T cells	Standard Deviation 0.00448601
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.0220367 percentage of CD8+ T cells	Standard Deviation 0.00571385
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0036667 percentage of CD8+ T cells	Standard Deviation 0.00404145
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0073333 percentage of CD8+ T cells	Standard Deviation 0.00945163
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0027100 percentage of CD8+ T cells	Standard Deviation 0.00186676
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0415883 percentage of CD8+ T cells	Standard Deviation 0.03264917
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 15	0.0033700 percentage of CD8+ T cells	Standard Deviation 0.00583701
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0106033 percentage of CD8+ T cells	Standard Deviation 0.01836551
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0006167 percentage of CD8+ T cells	Standard Deviation 0.0010681
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0051685 percentage of CD8+ T cells	Standard Deviation 0.00321239
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0045000 percentage of CD8+ T cells	Standard Deviation 0.00212132
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0002203 percentage of CD8+ T cells	Standard Deviation 0.00038163
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS2/4, Day 15	0.0280367 percentage of CD8+ T cells	Standard Deviation 0.03627084
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 105	0.0081933 percentage of CD8+ T cells	Standard Deviation 0.00716934
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0246667 percentage of CD8+ T cells	Standard Deviation 0.02247962
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0003180 percentage of CD8+ T cells	Standard Deviation 0.0003386
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0114300 percentage of CD8+ T cells	Standard Deviation 0.01150064
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 15	0.0260000 percentage of CD8+ T cells	Standard Deviation 0.04503332
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0005100 percentage of CD8+ T cells	Standard Deviation 0.00072125
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0164220 percentage of CD8+ T cells	Standard Deviation 0.01587121
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0488133 percentage of CD8+ T cells	Standard Deviation 0.05397085
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 15	0.0024100 percentage of CD8+ T cells	Standard Deviation 0.00301442
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0023883 percentage of CD8+ T cells	Standard Deviation 0.00272227
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 15	0.0051230 percentage of CD8+ T cells	Standard Deviation 0.00771231
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0015217 percentage of CD8+ T cells	Standard Deviation 0.0026356
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0009000 percentage of CD8+ T cells	Standard Deviation 0.00155885
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0383333 percentage of CD8+ T cells	Standard Deviation 0.04645787
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0696435 percentage of CD8+ T cells	Standard Deviation 0.07020651
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0005067 percentage of CD8+ T cells	Standard Deviation 0.00072507
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0800000 percentage of CD8+ T cells	Standard Deviation 0.11313708
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0056667 percentage of CD8+ T cells	Standard Deviation 0.0051316
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 15	0.0003867 percentage of CD8+ T cells	Standard Deviation 0.00066973
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 105	0.0005333 percentage of CD8+ T cells	Standard Deviation 0.00092376
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 105	0.0007567 percentage of CD8+ T cells	Standard Deviation 0.00131059
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0109367 percentage of CD8+ T cells	Standard Deviation 0.01894286
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 105	0.0130000 percentage of CD8+ T cells	Standard Deviation 0.01473092
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 105	0.0038700 percentage of CD8+ T cells	Standard Deviation 0.00670304
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 90 (Month 3)	0.0013300 percentage of CD8+ T cells	Standard Deviation 0.00135044
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0040167 percentage of CD8+ T cells	Standard Deviation 0.00695707
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.0284400 percentage of CD8+ T cells	Standard Deviation 0.02579343
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0266667 percentage of CD8+ T cells	Standard Deviation 0.04618802
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0120000 percentage of CD8+ T cells	Standard Deviation 0.02078461
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 15	0.0033333 percentage of CD8+ T cells	Standard Deviation 0.0057735
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 15	0.0326667 percentage of CD8+ T cells	Standard Deviation 0.04051337
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.0018967 percentage of CD8+ T cells	Standard Deviation 0.00184717
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0233333 percentage of CD8+ T cells	Standard Deviation 0.01527525
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 15	0.1193333 percentage of CD8+ T cells	Standard Deviation 0.06900242
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.0073200 percentage of CD8+ T cells	Standard Deviation 0.01007451
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 105	0.0653333 percentage of CD8+ T cells	Standard Deviation 0.06033517
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0053333 percentage of CD8+ T cells	Standard Deviation 0.0092376
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS2/4, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0120000 percentage of CD8+ T cells	Standard Deviation 0.00707107
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0423333 percentage of CD8+ T cells	Standard Deviation 0.03516153
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 15	0.0010000 percentage of CD8+ T cells	Standard Deviation 0.00173205
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.0070000 percentage of CD8+ T cells	Standard Deviation 0.005
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0090000 percentage of CD8+ T cells	Standard Deviation 0.01558846
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0002230 percentage of CD8+ T cells	Standard Deviation 0.00038625
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.0013333 percentage of CD8+ T cells	Standard Deviation 0.0023094
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.0683333 percentage of CD8+ T cells	Standard Deviation 0.08251263
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0116087 percentage of CD8+ T cells	Standard Deviation 0.01939586
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 105	0.0013333 percentage of CD8+ T cells	Standard Deviation 0.0023094
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0002253 percentage of CD8+ T cells	Standard Deviation 0.00039029
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 120 (Month 4)	0.0036667 percentage of CD8+ T cells	Standard Deviation 0.00635085
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.1460000 percentage of CD8+ T cells	Standard Deviation 0.21915291
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 15	0.0019520 percentage of CD8+ T cells	Standard Deviation 0.00148274
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0080000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.1486667 percentage of CD8+ T cells	Standard Deviation 0.20771455
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 15	0.0050000 percentage of CD8+ T cells	Standard Deviation 0.00458258
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.1503333 percentage of CD8+ T cells	Standard Deviation 0.19894807
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 15	0.0016667 percentage of CD8+ T cells	Standard Deviation 0.00288675
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.0060000 percentage of CD8+ T cells	Standard Deviation 0.006
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.0249567 percentage of CD8+ T cells	Standard Deviation 0.03147802
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.0307000 percentage of CD8+ T cells	Standard Deviation 0.04702863
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 15	0.0160000 percentage of CD8+ T cells	Standard Deviation 0.01969772
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS3, Day 15	0.0195800 percentage of CD8+ T cells	Standard Deviation 0.02908452
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 15	0.0023870 percentage of CD8+ T cells	Standard Deviation 0.00145326
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.0270000 percentage of CD8+ T cells	Standard Deviation 0.03044667
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 105	0.0013333 percentage of CD8+ T cells	Standard Deviation 0.0011547
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 105	0.0182000 percentage of CD8+ T cells	Standard Deviation 0.0301483
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.2550000 percentage of CD8+ T cells	Standard Deviation 0.34648232
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0005050 percentage of CD8+ T cells	Standard Deviation 0.00071418
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 105	0.0220000 percentage of CD8+ T cells	Standard Deviation 0.02029778
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 15	0.0046667 percentage of CD8+ T cells	Standard Deviation 0.00416333
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS2/4, Day 15	0.0230000 percentage of CD8+ T cells	Standard Deviation 0.02523886
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 15	0.0043333 percentage of CD8+ T cells	Standard Deviation 0.00585947
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0003415 percentage of CD8+ T cells	Standard Deviation 0.00048295
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.1763333 percentage of CD8+ T cells	Standard Deviation 0.25602799
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 30 (Month 1)	0.0026667 percentage of CD8+ T cells	Standard Deviation 0.0046188
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0134433 percentage of CD8+ T cells	Standard Deviation 0.02214271
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0040000 percentage of CD8+ T cells	Standard Deviation 0.0069282
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 105	0.0016067 percentage of CD8+ T cells	Standard Deviation 0.00278283
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0080000 percentage of CD8+ T cells	Standard Deviation 0.01385641
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 105	0.1756667 percentage of CD8+ T cells	Standard Deviation 0.14911181
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0080000 percentage of CD8+ T cells	Standard Deviation 0.01385641
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0008933 percentage of CD8+ T cells	Standard Deviation 0.0015473
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0002303 percentage of CD8+ T cells	Standard Deviation 0.00039895
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 105	0.0266667 percentage of CD8+ T cells	Standard Deviation 0.04532475
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0316667 percentage of CD8+ T cells	Standard Deviation 0.0310215
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0033333 percentage of CD8+ T cells	Standard Deviation 0.0057735
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0253333 percentage of CD8+ T cells	Standard Deviation 0.03106981
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.2006667 percentage of CD8+ T cells	Standard Deviation 0.22830097
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 15	0.0060000 percentage of CD8+ T cells	Standard Deviation 0.0103923
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0400000 percentage of CD8+ T cells	Standard Deviation 0.06928203
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 15	0.0012000 percentage of CD8+ T cells	Standard Deviation 0.00207846
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 105	0.0033333 percentage of CD8+ T cells	Standard Deviation 0.00305505
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0016367 percentage of CD8+ T cells	Standard Deviation 0.00283479
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0023333 percentage of CD8+ T cells	Standard Deviation 0.00404145
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS3, Day 105	0.1286667 percentage of CD8+ T cells	Standard Deviation 0.16850618
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0009000 percentage of CD8+ T cells	Standard Deviation 0.00155885
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0023333 percentage of CD8+ T cells	Standard Deviation 0.00404145
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 105	0.0008033 percentage of CD8+ T cells	Standard Deviation 0.00139141
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 15	0.0043333 percentage of CD8+ T cells	Standard Deviation 0.00378594
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 15	0.0426667 percentage of CD8+ T cells	Standard Deviation 0.05021288
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0018367 percentage of CD8+ T cells	Standard Deviation 0.0031812
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0312150 percentage of CD8+ T cells	Standard Deviation 0.02010305
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0120000 percentage of CD8+ T cells	Standard Deviation 0.02078461
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0323333 percentage of CD8+ T cells	Standard Deviation 0.01778576
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 15	0.0034367 percentage of CD8+ T cells	Standard Deviation 0.00324179
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 105	0.0038700 percentage of CD8+ T cells	Standard Deviation 0.00670304
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 105	0.0390000 percentage of CD8+ T cells	Standard Deviation 0.0087178
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0035200 percentage of CD8+ T cells	Standard Deviation 0.00304882
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0038233 percentage of CD8+ T cells	Standard Deviation 0.0033225
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 105	0.0010800 percentage of CD8+ T cells	Standard Deviation 0.00187061
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0022283 percentage of CD8+ T cells	Standard Deviation 0.00320135
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.2116667 percentage of CD8+ T cells	Standard Deviation 0.21159946
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0018300 percentage of CD8+ T cells	Standard Deviation 0.00316965
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0032033 percentage of CD8+ T cells	Standard Deviation 0.00444653
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-4, prME, Day 105	0.0176667 percentage of CD8+ T cells	Standard Deviation 0.01703917
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS2/4, Day 360 (Month 12)	0.0035050 percentage of CD8+ T cells	Standard Deviation 0.00495682
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0029790 percentage of CD8+ T cells	Standard Deviation 0.00433441
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 15	0.0760000 percentage of CD8+ T cells	Standard Deviation 0.06919538
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 15	0.0033267 percentage of CD8+ T cells	Standard Deviation 0.00357693
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-1, prME, Day 15	0.0004900 percentage of CD8+ T cells	Standard Deviation 0.0008487
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS2/4, Day 15	0.2126667 percentage of CD8+ T cells	Standard Deviation 0.24855851
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 30 (Month 1)	0.0058683 percentage of CD8+ T cells	Standard Deviation 0.00636956
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0021250 percentage of CD8+ T cells	Standard Deviation 0.0030052
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 15	0.0052593 percentage of CD8+ T cells	Standard Deviation 0.00613561
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 90 (Month 3)	0.0062367 percentage of CD8+ T cells	Standard Deviation 0.00856318
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0059600 percentage of CD8+ T cells	Standard Deviation 0.00785521
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0773333 percentage of CD8+ T cells	Standard Deviation 0.06971609
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 105	0.0046667 percentage of CD8+ T cells	Standard Deviation 0.0080829
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 105	0.0043933 percentage of CD8+ T cells	Standard Deviation 0.00382467
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 90 (Month 3)	0.0045720 percentage of CD8+ T cells	Standard Deviation 0.00505935
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS3, Day 360 (Month 12)	0.0006650 percentage of CD8+ T cells	Standard Deviation 0.00094045
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0075367 percentage of CD8+ T cells	Standard Deviation 0.01031316
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0050000 percentage of CD8+ T cells	Standard Deviation 0.00707107
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 15	0.0007403 percentage of CD8+ T cells	Standard Deviation 0.00074504
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 30 (Month 1)	0.0102833 percentage of CD8+ T cells	Standard Deviation 0.01232115
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.0526667 percentage of CD8+ T cells	Standard Deviation 0.09122134
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 30 (Month 1)	0.0037760 percentage of CD8+ T cells	Standard Deviation 0.00368127
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-1, prME, Day 15	0.0023033 percentage of CD8+ T cells	Standard Deviation 0.00203952
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 105	0.0533333 percentage of CD8+ T cells	Standard Deviation 0.06880649
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 120 (Month 4)	0.0015990 percentage of CD8+ T cells	Standard Deviation 0.00101474
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 105	0.0004400 percentage of CD8+ T cells	Standard Deviation 0.0007621
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 90 (Month 3)	0.0060000 percentage of CD8+ T cells	Standard Deviation 0.0103923
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, NS5, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 90 (Month 3)	0.0009200 percentage of CD8+ T cells	Standard Deviation 0.00159349
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 105	0.0080000 percentage of CD8+ T cells	Standard Deviation 0.01216553
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 30 (Month 1)	0.0003040 percentage of CD8+ T cells	Standard Deviation 0.00052654
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0426667 percentage of CD8+ T cells	Standard Deviation 0.06379133
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 90 (Month 3)	0.0006667 percentage of CD8+ T cells	Standard Deviation 0.0011547
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 120 (Month 4)	0.0009333 percentage of CD8+ T cells	Standard Deviation 0.00161658
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2-, TNFa+, DENV-2, NS1, Day 15	0.0126667 percentage of CD8+ T cells	Standard Deviation 0.02193931
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-1, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 105	0.0066967 percentage of CD8+ T cells	Standard Deviation 0.00634139
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 120 (Month 4)	0.0093333 percentage of CD8+ T cells	Standard Deviation 0.01137248
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0007800 percentage of CD8+ T cells	Standard Deviation 0.001351
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 105	0.0053333 percentage of CD8+ T cells	Standard Deviation 0.00757188
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 30 (Month 1)	0.0008400 percentage of CD8+ T cells	Standard Deviation 0.00145492
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 90 (Month 3)	0.0046667 percentage of CD8+ T cells	Standard Deviation 0.0080829
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-1, prME, Day 360 (Month 12)	0.0070000 percentage of CD8+ T cells	Standard Deviation 0.00848528
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 30 (Month 1)	0.0020000 percentage of CD8+ T cells	Standard Deviation 0.0034641
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS2/4, Day 15	0.0053333 percentage of CD8+ T cells	Standard Deviation 0.00378594
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0045000 percentage of CD8+ T cells	Standard Deviation 0.00494975
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 360 (Month 12)	0.0060000 percentage of CD8+ T cells	Standard Deviation 0.00848528
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 120 (Month 4)	0.0013333 percentage of CD8+ T cells	Standard Deviation 0.0023094
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-2, prME, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 120 (Month 4)	0.0003333 percentage of CD8+ T cells	Standard Deviation 0.00057735
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 120 (Month 4)	0.0029540 percentage of CD8+ T cells	Standard Deviation 0.00453868
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 15	0.0251227 percentage of CD8+ T cells	Standard Deviation 0.03459943
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 105	0.0070000 percentage of CD8+ T cells	Standard Deviation 0.00888819
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 15	0.0011667 percentage of CD8+ T cells	Standard Deviation 0.00202073
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 30 (Month 1)	0.0724367 percentage of CD8+ T cells	Standard Deviation 0.10037912
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 90 (Month 3)	0.0023333 percentage of CD8+ T cells	Standard Deviation 0.00404145
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, prME, Day 105	0.0056667 percentage of CD8+ T cells	Standard Deviation 0.00737111
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 90 (Month 3)	0.0842333 percentage of CD8+ T cells	Standard Deviation 0.14123712
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 30 (Month 1)	0.0040000 percentage of CD8+ T cells	Standard Deviation 0.00458258
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0129300 percentage of CD8+ T cells	Standard Deviation 0.01662924
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 105	0.0353100 percentage of CD8+ T cells	Standard Deviation 0.05329149
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, NS1, Day 15	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 120 (Month 4)	0.1106733 percentage of CD8+ T cells	Standard Deviation 0.17709757
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 360 (Month 12)	0.0377150 percentage of CD8+ T cells	Standard Deviation 0.01030255
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 360 (Month 12)	0.0095000 percentage of CD8+ T cells	Standard Deviation 0.0106066
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS1, Day 360 (Month 12)	0.0108285 percentage of CD8+ T cells	Standard Deviation 0.01438467
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 120 (Month 4)	0.0053333 percentage of CD8+ T cells	Standard Deviation 0.0092376
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-1, prME, Day 120 (Month 4)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 15	0.2024327 percentage of CD8+ T cells	Standard Deviation 0.30965583
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa-, DENV-3, prME, Day 90 (Month 3)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 30 (Month 1)	0.2125000 percentage of CD8+ T cells	Standard Deviation 0.20614012
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 30 (Month 1)	0.0002883 percentage of CD8+ T cells	Standard Deviation 0.00049941
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 90 (Month 3)	0.2045333 percentage of CD8+ T cells	Standard Deviation 0.26081536
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, prME, Day 15	0.0170000 percentage of CD8+ T cells	Standard Deviation 0.02944486
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 120 (Month 4)	0.0023333 percentage of CD8+ T cells	Standard Deviation 0.00404145
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 105	0.1804967 percentage of CD8+ T cells	Standard Deviation 0.22221367
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 360 (Month 12)	0.0277150 percentage of CD8+ T cells	Standard Deviation 0.0151533
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-4, prME, Day 360 (Month 12)	0.0170000 percentage of CD8+ T cells	Standard Deviation 0.02404163
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 120 (Month 4)	0.2122567 percentage of CD8+ T cells	Standard Deviation 0.28717008
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2+, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0104300 percentage of CD8+ T cells	Standard Deviation 0.01696039
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS2/4, Day 360 (Month 12)	0.2921435 percentage of CD8+ T cells	Standard Deviation 0.3919401
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 120 (Month 4)	0.0083333 percentage of CD8+ T cells	Standard Deviation 0.01443376
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-3, prME, Day 120 (Month 4)	0.0053067 percentage of CD8+ T cells	Standard Deviation 0.00378127
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 15	0.1204393 percentage of CD8+ T cells	Standard Deviation 0.09431396
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 90 (Month 3)	0.0043333 percentage of CD8+ T cells	Standard Deviation 0.00750555
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 30 (Month 1)	0.4185000 percentage of CD8+ T cells	Standard Deviation 0.53648089
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 15	0.0020167 percentage of CD8+ T cells	Standard Deviation 0.00122676
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 90 (Month 3)	0.4077633 percentage of CD8+ T cells	Standard Deviation 0.53498698
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 90 (Month 3)	0.0061467 percentage of CD8+ T cells	Standard Deviation 0.00600538
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 30 (Month 1)	0.0023333 percentage of CD8+ T cells	Standard Deviation 0.00208167
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 105	0.2482033 percentage of CD8+ T cells	Standard Deviation 0.29841232
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, C, Day 30 (Month 1)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-4, prME, Day 120 (Month 4)	0.0123333 percentage of CD8+ T cells	Standard Deviation 0.01721434
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS3, Day 120 (Month 4)	0.2656767 percentage of CD8+ T cells	Standard Deviation 0.28387658
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 360 (Month 12)	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 120 (Month 4)	0.0070000 percentage of CD8+ T cells	Standard Deviation 0.01212436
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-3, prME, Day 30 (Month 1)	0.0049517 percentage of CD8+ T cells	Standard Deviation 0.00371622
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 15	0.0337727 percentage of CD8+ T cells	Standard Deviation 0.01914939
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 105	0.0000000 percentage of CD8+ T cells	Standard Deviation 0
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa-, DENV-2, C, Day 15	0.0033333 percentage of CD8+ T cells	Standard Deviation 0.0057735
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 30 (Month 1)	0.1478333 percentage of CD8+ T cells	Standard Deviation 0.11273901
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg-, IL2+, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.0059367 percentage of CD8+ T cells	Standard Deviation 0.01028261
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa-, DENV-4, prME, Day 15	0.0002477 percentage of CD8+ T cells	Standard Deviation 0.00042897
TDV: DENV Immune: DENV-3 Positive	Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)	IFNg+, IL2-, TNFa+, DENV-2, NS5, Day 90 (Month 3)	0.1278067 percentage of CD8+ T cells	Standard Deviation 0.11606138

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026

Immunogenicity and Safety of Tetravalent Dengue Vaccine Candidate (TDV) in Flavivirus-Naïve and Dengue-Immune Adults

Conditions

Keywords

Brief summary

Detailed description

Related papers

Interventions

Sponsors

Study design

Eligibility

Inclusion criteria

Exclusion criteria

Design outcomes

Primary

Secondary

Countries

Participant flow

Recruitment details

Pre-assignment details

Participants by arm

Withdrawals & dropouts

Baseline characteristics

Adverse events

Outcome results

Geometric Mean Titers (GMT) of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 15

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 105

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 120 (Month 4)

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 150 (Month 5)

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 180 (Month 6)

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 270 (Month 9)

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 30 (Month 1)

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 360 (Month 12)

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 60 (Month 2)

GMT of Neutralizing Antibodies for Each of the Four Dengue Serotypes at Day 90 (Month 3)

Duration of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination

Level of Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination

Magnitude of Cellular Immune Response Assessed by Number of Spot Forming Cells [SFC]/10^6 Peripheral Blood Mononuclear Cells (PBMCs) Measured by IFN-γ ELISpot Responses to TDV

Percentage of Participants With at Least One Unsolicited Adverse Events (AEs) Following Each Vaccination

Percentage of Participants With Interferon-gamma (IFN-γ) Enzyme-linked Immunospot (ELISpot) Responses to Tetravalent Dengue Vaccine (TDV)

Percentage of Participants With Medically Attended AEs (MAAEs)

Percentage of Participants With Serious Adverse Events (SAEs)

Percentage of Participants With Solicited Local (Injection Site) Reactions Following Each Vaccination

Percentage of Participants With Solicited Systemic Reactions Following Each Vaccination

Percentage of Participants With Vaccine Viremia for Each of the Four Vaccine Strains After Vaccination

Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD4+ T Cells by Intracellular Cytokine Staining (ICS)

Phenotype Characterization of Cellular Immune Response to TDV Assessed as Percentage of Total CD8+ T Cells by Intracellular Cytokine Staining (ICS)