MSI in Circulatory DNA of Endometrial Cancer

A Compare of Microsatellite Instability in Circulatory DNA and Tumor Tissue of Endometrial Cancer

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03744962

Enrollment

100

Registered

2018-11-19

Start date

2018-11-10

Completion date

2020-12-23

Last updated

2018-11-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Circulating Tumor Cell, Endometrial Cancer, Lynch Syndrome, Microsatellite Instability

Brief summary

This study aims to analyze the microsatellite instability (MSI) in the circulatory tumor DNA and in the tumor tissue in the patients diagnosed with uterine endometrial cancer. These data will be used for the study of Cohort Study of Universal Screening for Lynch Syndrome in Chinese Patients of Endometrial Cancer (NCT03291106, clinicaltrials.gov).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Inclusion criteria

* Confirmed primary endometrial cancer before any surgical or chemotherapy treatment * Signed an approved informed consents * Feasible for sampling

Exclusion criteria

* Not meeting all of the inclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
Frequency of microsatellite instability	Two years	Frequencies of different status of microsatellite instability (high microsatellite instability or microsatellite-stable) in the circulatory tumor DNA and in the tumor tissue

Countries

China

Contacts

Primary ContactLei Li, M.D.

lileigh@163.com13911988831

Outcome results