Anoxic-Ischemic Encephalopathy
Conditions
Brief summary
There are 3 levels of severity of anoxo-ischemic encephalopathy (EAI): mild, moderate and severe. Therapeutic hypothermia is beneficial in children with moderate EAI. It is ineffective in severe EAI and may be deleterious if there is no EAI. He continues to question his interest in light EAIs. There are few studies on the becoming of children with a mild anoxic-ischemic encephalopathy and not set hypothermia. The main hypothesis of the study is that term newborns with anoxo-ischemic encephalopathy who did not require therapeutic hypothermia have normal psychomotor development at 2 years.
Interventions
OTHERQuestionaire
Evaluation of psychomotor development in children with mild EAI without indication of therapeutic hypothermia. Precise analysis of the type (motor, sensory, language, epilepsy) and the severity of sequelae by sending a questionnaire to parents. Investigation of early, clinical and paraclinical prognostic factors of good or bad neurodevelopmental outcome. Evaluation of the height-weight growth and the cranial perimeter
Sponsors
Hospices Civils de Lyon
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
2 Years to 7 Years
Inclusion criteria
* Full-term children, gestational age\> 36 weeks of amenorrhea * Between the 1st of January 2012 and the 31st of December 2016 * Hospitalized in the neonatal resuscitation department of Croix Rousse in Lyon * Perinatal asphyxia with clinical signs of encephalopathy * Indication of therapeutic hypothermia not retained because EAI mild * Where parents were informed and did not object to participation in the study
Exclusion criteria
* Dysmorphic syndrome * Stroke * Children transferred for other criteria (respiratory distress, heart failure ...)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Existence of abnormalities | maximum 1 years | Abnormalities researched are : abnormal motor, sensory (auditory or visual), delayed psychomotor acquisition compared to the expected (norms), or epilepsy at 2 years. These anomalies will be collected by sending a questionnaire to the parents. |
Countries
France
Outcome results
None listed