Effect of Diet on Breast Milk Composition
Conditions
Keywords
Breast Milk, Mediterranean Diet
Brief summary
This study is a nutrition research study designed to look at how healthy meals can influence the content of breast milk. Moms will be provided with meals that follow a Mediterranean diet pattern for 4 weeks. The goal of the study is to see if breast milk content changes over the 4 week period. The infants of the moms will also be included in the study to measure any changes in growth.
Interventions
OTHERMediterranean Diet
Participants will be provided with meals that follow a Mediterranean meal plan.
Sponsors
Arkansas Children's Hospital Research Institute
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* ≤4.5 months postpartum * BMI 30 - 50 kg/m2 * ≥ 18 years of age * Singleton pregnancy * Exclusive breastfeeding and plans to exclusively breastfeed for at least 6 months postpartum * Mother has a breast pump * Mother is willing to collect breast milk for a 24 hour period.
Exclusion criteria
* Pre-existing conditions (e.g. diabetes, hypertension, heart disease) * Use of recreational drugs, tobacco, or alcohol * Use of medications or supplements for which breastfeeding is contraindicated * Child has internal metal which may be an NMR safety concern
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in breast milk fat concentration by mid-infrared spectroscopy | The change in breast milk fat concentration will be assessed by mid-infrared spectroscopy by measuring the concentration before the participants begin the dietary intervention, 2 weeks into the intervention, and at the end of the 4-week intervention. | The primary aim is to test whether the dietary intervention modifies the breast milk fat concentration of obese mothers. |
Countries
United States
Outcome results
None listed