Elderly Patients, Metastatic Neoplasia, Systemic Treatment
Conditions
Keywords
quality of life, elderly, metastatic neoplasia, systemic therapies
Brief summary
The aim of this study is to describe the impact of : Geriatric intervention contribution on quality of life of elderly patients receiving systemic treatments for metastatic neoplasia
Detailed description
Elderly cancer incidence increases exponentially with advancing age. However, elderly patients are largely underrepresented in cancer treatment trials. The geriatric population presents particular physical, mental, psychological or social specificities that may condition the prognosis especially for patients with metastatic neoplasia. Recently, the measurement of quality of life (QoL) in aging population is being recognized as an important part of clinical decision. It is therefore essential to set up prospective studies to evaluate the impact of oncogeriatric practices on the quality of life of elderly patients with metastatic neoplasia. The main objective of this prospective study is to describe the contribution of geriatric intervention on quality of life for for elderly (\> 75 years) with metastatic solid cancer receiving systemic treatment during the first 6 months of their therapeutic management.
Interventions
Geriatric intervention
Sponsors
Institut de Cancérologie de la Loire
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
75 Years to No maximum
Inclusion criteria
* Patient with solid metastatic neoplasia * 75 years old or more * Men or women * ECOG between 0 and 3 * Patient receiving systemic antineoplasic treatment (chemotherapy, hormonotherapy, immunotherapy, targeted therapy)
Exclusion criteria
* ECOG 4 * Localized cancer * Patients already included in a study witch could modify quality of life * Patient unable to give their consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Level of quality of life | 6 months | Level of quality of life will be measured with the QoL ELD 14 (Quality Qf Life ELDerly patients with 14 Questions) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Duration of hospitalizations | 6 months | Duration of hospitalizations will be reported in hours |
| Number of toxicities ( grade 3 and 4) | 6 months | Number of toxicities (grade 3 and 4) will be reported according to the CTCAE v4.0 (Common Terminology Criteria for Adverse Events) |
| number of hospitalizations | 6 months | number of hospitalizations will be reported |
Countries
France
Outcome results
None listed