Pregnancy Early
Conditions
Brief summary
The effects of vitamin D2 supplement during pregnancy on postpartum maternal and fetal vitamin D levels: the randomized controlled trial
Detailed description
Vitamin D structurally similar to steroids. Made from the skin. And metabolism of the liver, kidneys, vitamin D levels in the bloodstream are two types of vitamin D 2 (Ergocalciferol) and vitamin D 3 (Cholecalciferol) Vitamin D regulates calcium and phosphorus levels in the body. Including the accumulation of minerals in the bone. Vitamin D is important in the formation of bones and teeth and the normal growth of children, affects the reabsorption of amino acids in the kidneys, regulates the amount of calcium and phosphorus in the blood Vitamin D deficiency in pregnant affects the mother and baby example high maternal blood pressure during pregnancy, diabetes during pregnancy, increase birth body weight of baby. low calcium seizures Infants, baby have bones and growth disorders. Currently, no vitamin D supplement is used in pregnant women in Thailand who attend antenatal clinics. The researcher has proposed to study the effects of vitamin D supplement during pregnancy on postpartum maternal and fetal vitamin D levels by using vitamin D 20,000IU / week
Interventions
DRUGCalciferol
calciferol capsule
DRUGPlacebo
placebo capsule
Sponsors
Department of Medical Services Ministry of Public Health of Thailand
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Women who have pregnant and ANC at Rajavithi hospital * Women who have age at least 18 year * Women who have Thai nationality * Women who have pregnant of gestational age under 20week
Exclusion criteria
* Women who don't plan of delivered at Rajavithi hospital * Women who have complication of pregnancy * Woman who delivered before gestational age 37week * Women who have abnormal kidney function * Woman who have been used anticonvulsant drug or others form of vitamin d * Women who have vitamin d allergy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| effect of vitamin D 2 supplementation during pregnancy | within 30 minute after delivered | To study the effect of vitamin D 2 supplementation during pregnancy on postpartum maternal and fetal vitamin D levels effects of vitamin D2 supplement during pregnancy on postpartum maternal and fetal vitamin D levels |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| vitamin D levels in maternal blood during pregnancy | at first time ANC | To assess vitamin D levels in maternal blood during pregnancy |
| vitamin D levels in maternal blood after vitamin D supplementation | within 30 minute after delivered | To assess vitamin D levels in maternal blood after vitamin D supplementation during pregnancy |
Countries
Thailand
Outcome results
None listed