Altitude Hypoxia
Conditions
Brief summary
The investigators expect to find that different intensity and altitude exposure levels will show what kind of intermittent exposure protocol is more beneficial to athletes and healthy individuals that experience acute exposure to altitude during exercise. This may furthermore be related to acute altitude exposure for recreational exercise use as well.
Interventions
OTHERSimulated altitude
Participants will exercise in simulated altitude will range between 2100 feet and 16400 feet and will increase according to arm guidelines
OTHERPlacebo simulated altitude
Participants will exercise at sea level at similar percentage of intensities to the simulated altitude group.
Sponsors
Mayo Clinic
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* 18-70 years of age, * history of good health, * generally active to competitive athletes.
Exclusion criteria
* History of cardiac or pulmonary disease, * not currently active, * unable to exercise or meet study requirements (e.g., number of sessions), * live at altitude (\>2,100m or 7,000ft).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in hemoglobin | Baseline, 2-week, 4-week, 6-week, and 8-week |
| Change in hematocrit | Baseline, 2-week, 4-week, 6-week, and 8-week |
| Change in erythropoietin | Baseline, 2-week, 4-week, 6-week, and 8-week |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in peak VO2 | Baseline and 6- and 8-week | Change from maximal exercise test performed at sea level |
| Change in cycling performance at altitude | Baseline and 6- and 8-week | change in aerobic/anaerobic cycling performance at altitude |
Countries
United States
Outcome results
None listed