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Influence of Extracorporeal Circulation on the Development of OSA (Obstructive Sleep Apnea)

Influence of Extracorporeal Circulation on the Development of OSA (Obstructive Sleep Apnea)

Status
Withdrawn
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03743090
Enrollment
0
Registered
2018-11-15
Start date
2019-08-01
Completion date
2020-04-10
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary Artery Disease

Keywords

coronary artery disease, obstructive sleep apnea

Brief summary

* 1\. Coronary artery bypass grafting (CABG) could be performed with or without extracorporeal circulation (ECC). * 2\. OSA (Obstructive Sleep Apnea) could be influenced by in intravenous perfusion. * 3\. ECC could influence the amount of intravenous perfusion administered to the patient. The aim of this study was to examine the influence of ECC on the development of OSA.

Detailed description

* 1\. Coronary artery bypass grafting (CABG) could be performed with or without extracorporeal circulation (ECC). * 2\. OSA (Obstructive Sleep Apnea) could be influenced by in intravenous perfusion. * 3\. ECC could influence the amount of intravenous perfusion administered to the patient. The aim of this study was to examine the influence of ECC on the development of OSA. The AHI (Apnea Hypopnea Index) will be used to assess this potential influence.

Interventions

DIAGNOSTIC_TESTPolysomnography.

A polysomnography will be performed for all of the patients the day before surgery (value of reference), and on the second postoperative day (in order to examine the influence of ECC on the development of OSA).

Sponsors

Astes
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* All of the patients scheduled for an elective CABG

Exclusion criteria

* Patient's refusal

Design outcomes

Primary

MeasureTime frameDescription
Change in the AHI3 daysChange from baseline AHI (Apnea Hypopnea Index, which is the average amount of apnea and hypopnea per four of sleep) at the 3rd postoperative day. The AHI is derived from the polysomnography which will be performed to all of the patients the day before surgery and the 3rd postoperative day.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026